Petaurus breviceps papuanus (sugar glider): 138169865
Help
Entry
138169865 CDS
T10505
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
pbrv Petaurus breviceps papuanus (sugar glider)
Pathway
pbrv05012
Parkinson disease
pbrv05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
pbrv00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
138169865 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
138169865 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbrv01001
]
138169865 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pbrv04131
]
138169865 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pbrv04147
]
138169865 (LRRK2)
Enzymes [BR:
pbrv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
138169865 (LRRK2)
Protein kinases [BR:
pbrv01001
]
Serine/threonine kinases: TKL group
LRRK family
138169865 (LRRK2)
Membrane trafficking [BR:
pbrv04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
138169865 (LRRK2)
Exosome [BR:
pbrv04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
138169865 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
PK_Tyr_Ser-Thr
Pkinase
LRR_8
LRR_4
Roc
COR
Ras
LRR_14
LRR_9
LRR_NXF1-5
Ank_2
Arf
LRR_13
T2SSE
nSTAND3
PduV-EutP
MMR_HSR1
Beta-prop_RSE1_2nd
AAA_16
AAA_22
GTP_EFTU
AAA_7
Septin
Beta-prop_EML_2
cobW
NACHT
FtsK_SpoIIIE
ABC_tran
CARF_Card1
AAA_29
TniB
ResIII
MobB
LRR_6
AAA_14
Motif
Other DBs
NCBI-GeneID:
138169865
NCBI-ProteinID:
XP_068955563
LinkDB
All DBs
Position
Unknown
AA seq
2524 aa
AA seq
DB search
MASSCSLGVEEEEEETLKKLIVRLQNVQEGKQIETLIQILEDMLMLTYSEHASKLFQGKN
IHMPLLLVLDSYMRVAGVQQVGWSLLCKLTEICPDIMQNLMGPQDVGKDWEVLGVHQLIL
KMLTVHNANRVLSVIGLKALDQLLTSDLMTLRILEEDCSDVFTLIFDAMHTFTANEEIQK
FGCKILHVLFEKVSEEQLTEFIENNDYMFLLNALKRFNHEEEVVLHVLHSLHSLALPCSN
VEVLMSGNVRCYNIVVEAMKMFSSSEKIQEIGCCLLHRLTLDNFFNILVLNEVHEVIVKA
LKKYSENATLQTAALSCLTLLTETIILNQDLEEKKKNQGDNEDNKLYWLEASYRALTLHR
KNTDVQEAACWALNSLLVYQSNLHENIGDEDDQYPVHREILLSMLMHSSSKEVFQAAANA
LSTLSEQNVNVRKALLSKGIYWNVLQIMMKHLNFPQVAESGCKMLNHLLEGSNLHLDVMA
SVTSKIIKVMKSHKTSSTVQLEALQTILHIIVPESKKEPEEDALLNVNLKVVKNQCLLND
IHKLVLGALNKFIGNPGIQICGLKIISSLVNCSGALEMFSQQGALDSVLHTLQMYPGDRA
IQCLGLSLLGSLITKENLCTETQDLLANILVSSLKRFKDVVEVQISGFQTTLTILELSLG
FAKLLLSHHSYDSLIFYQMSRCFTEQTDNQFQNLCCEVFAKITCDDDIKNVLLAKACEEN
NSIMAECLLLLGADINKVIGKTSLICQACEKESSPKLVELLLNNGSREQEIRKALMISIK
KNNSQIISLLLRKLGLDQVNSSICLGGFCLGKIEPSWLSPLFLDKVSNLRKQTNTGSALA
RMVVRYQMKNLSENGPISGSDGSFPEDHLDQFSDWTVIPESSVDCVFHHSDDLDSEGSDG
SFLMKKKSSSFNVRDLALQCESPTLERHSNSMEVSFDHEELLKEKRGLFSSRDSVQGSSK
FQCHLRGSDSFFPLTSEREYIKSLDLSANELEDIDGISKKCCLSDHLTRLEKLELHQNAL
TRIPQQLCETLKCLKYLDLHSNKITSVPAYLFKMNCIANLDISRNDIGPSIILDPTIRCP
TLKQINLSYNQLSSVPEFHADVIENLEHLLLEGNKISEIYSPLCLKELKILNLSKNHISS
ITEDFFEACCKLEVFSARMNLLVAVPCLPSSITILNLSQNKFTCIPEVILSLPHLRSLDL
SSNEIYSLPGPAHWKSLNLRELLFNHNQISILDLSEKAYTWSRMEKLHLSHNKLKEIPPE
IGFLENLTSLDVSYNLELRSFPNEMGKLTKIWDLPLDELHLNFDFKHIGCKARDIIRFLQ
QRLKKAVPYNRMKLMVVGNTGSGKTTLLQQLMKYKRTDLSTPNTTIGIDVKDWSIQLRNK
GKKELILNVWDFSGREEFYSAHPHFMTQRALYLAVYDLSKGHTEIDAMKPWLFNIKARAS
SSPVILVGTHLDVSDEKRRKDSISKITKELLNKRVFPEIRAYHFVNATEEYDALVKLRKS
IVKESLNFKIRDQPVVGQLIPDCYLELEKKILLERKNVPIEFPVISQKRLVQLVKESQLQ
LDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKMMAQILTVKVEGFAKYPK
GIIQRSDVEKFLSKKSRFPKNYMSQYFKLLEKFQIALPIGEEHLLVPSSLSDQRPVIELP
HCENSEVIVRVYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYLNWS
PEAYCLVESSILDNSSESSLKITAPSCRKGCIILGQVVDHIDSLMEEWFPGLLEIDVCGE
GETLLKKWALYSFNDGEAQQKILLDDLMKKTEEGDLLINPDEPRLTIPIGHIAPDLILAD
MPRNIMLNNDELEFKQAPEFLLGDGGFGSVYRASYKGEEVAVKIFNKHTSLRLLRQELAV
LCHLHHPSLISLLAAGIRPRMLVIELASKGSLDQLLQRDKASLTRALQHRIALHVADGLR
YLHESMIIYRDLKPHNVLLFTLYPNSAIIAKIADYGIAQYCCRMGIKTSEGTAGFRAPEV
AKGNVIYNQQADIYSFGLLLYDILTTGGRILEGLKFPNEFDELAIHGRLPDPVKEYGCTP
WPKVENLIKKCLKENPQERPTSAQVYEILNSAELICLRRYILIPKIFVAECMVATNQSSK
NAVIWLGSGNNDTGQLSCLEINTERHISKDMTESRILCLALVYLLVEKESWIVAGTQSGT
LLAVKTEDDKKGHMLQRMTDSVTCLYCNSFSKQSKQKNFLLVGTANGRLAIFEDRNVKFE
GAPPLKTLNIGNVSTPLMCLNESIYSSEKSVIWGGCGTKIFSLSNDFSIQKLIETKTNQL
FSYATFSDANIISIVVDKAIYVAKKNSHFVEVWDKNTEKLCVLIDCAQFLKDHTVILNKE
SNHKMTYSGRVKTLCLQKNTALWIGTGGGHILLVDLSTHRIIHIIQNFCNSIRALMTVQL
GSLKNVMLVLGYCQKSNENTPTQKEMESCLSIWDINLPHEVENLKKHTEVRRELGEKMRS
FSME
NT seq
7575 nt
NT seq
+upstream
nt +downstream
nt
atggccagtagttgcagcctcggggttgaagaagaagaagaggaaaccctgaagaagttg
atagttaggctgcaaaatgtccaggagggaaaacagatagaaaccctgatccagatacta
gaggatatgctgatgttaacgtactctgagcacgcttctaagttatttcaaggcaaaaat
atccatatgcctttgctgcttgttttggattcttacatgagagtcgcaggtgtgcaacag
gtgggctggtcacttctttgtaaactgacagaaatttgtcctgatataatgcaaaactta
atgggtccccaggatgttggaaaggattgggaagtgcttggtgttcaccagctgattctc
aaaatgctcactgttcacaatgctaatagagttctttcagtgattggactgaaggcatta
gatcagctcctgacttcagatctgatgactttgcggatattggaagaagattgcagtgat
gtgttcacattaatttttgatgccatgcatacatttactgctaatgaagagatccaaaag
tttggctgtaaaattttacatgtgctttttgagaaagtttcagaagaacaactgactgaa
tttatcgagaacaatgattatatgtttttgctgaatgcattaaaaagatttaatcatgaa
gaagaagttgttcttcatgttctacacagtttacattccctagcactcccatgtagtaat
gttgaagtcttaatgagtggaaatgtcagatgttacaatattgtggtagaagccatgaaa
atgttctctagcagtgaaaaaattcaagaaattggttgctgtttgttacacaggcttaca
ttggataatttctttaatatcctggttttaaatgaagttcatgaggttatcgtgaaagct
cttaaaaaatattcagaaaatgcaaccttacagactgcagcactaagctgtttgactctc
ctcactgaaactattattttaaaccaagatctagaagaaaagaaaaagaatcagggcgat
aatgaggacaacaagttatactggttagaagccagttacagagcgttgaccctgcataga
aagaacacagatgtgcaggaggctgcatgctgggctttaaacagtctacttgtgtaccaa
agcaatttacatgaaaatattggcgatgaagacgaccagtatccagtgcatagagaaata
ctactttccatgctgatgcattcttcatcaaaagaagtatttcaggcggctgctaatgca
ttgtcaactctatcagaacaaaatgttaatgtcagaaaagccctgttgtcaaaaggaata
tactggaatgtactacagataatgatgaagcacttaaactttcctcaagtggctgaaagt
ggatgtaaaatgttaaatcatcttttggaaggaagtaatcttcatctagatgtaatggcc
tctgtgacatctaaaataataaaagttatgaaaagtcacaaaacctcatcaacagtgcag
ctggaagcacttcaaactattttacatattattgtcccagaatcaaagaaagaacctgaa
gaagatgctttattaaatgtaaatctaaaagtggttaaaaaccagtgcctattgaatgac
attcacaaactggttctaggtgctttaaataagtttattggaaatcctggaattcaaata
tgtggattaaaaataatttcttctttagtaaattgttctggagcattagaaatgttttct
caacaaggagcccttgattccgtacttcatacactacagatgtatccaggtgacagagca
attcagtgccttggtctgagtctactaggatctttgattacaaaagagaatttgtgcaca
gaaactcaggatctgcttgcaaatattctggtttccagcttaaaacgatttaaggatgtt
gttgaagtacagataagtggatttcaaacaactttgacaatacttgaattatcacttggt
tttgcaaagctgctgctaagtcatcattcatatgactcactaattttctatcagatgtcc
aggtgtttcactgaacaaacagataatcagtttcagaatctttgttgtgaagtctttgcc
aaaataacttgtgatgatgatattaaaaatgtactactggcaaaagcctgtgaggaaaac
aatagcattatggccgaatgtctcctccttttgggagctgatattaataaagtgattgga
aaaacttctttgatctgccaggcttgtgaaaaggaaagcagtcccaaattagtggaactc
ttattaaataatgggtcacgagaacaagagattcggaaggcattgatgatcagcataaag
aaaaataacagtcaaatcatcagtttactgttaaggaaacttggcctggatcaggtcaat
agcagtatttgtcttggaggattttgtcttggaaaaatagaaccttcatggctgagtcct
ttatttctagataaagtatctaatttaagaaagcaaacaaacacaggatctgcattggca
agaatggtagtaagatatcaaatgaaaaatttatcggaaaatggacctatatcaggcagt
gatggaagttttcctgaagatcatcttgatcaatttagtgattggactgttatacctgag
tcttctgtagactgtgtatttcatcacagtgatgatcttgatagtgaaggaagtgatggt
tcatttcttatgaaaaagaaatcgagttcttttaatgtgagagatcttgccttgcagtgt
gagtcaccaactttggaaaggcattctaattcaatggaggtcagttttgatcatgaagaa
ctgttgaaggaaaaaagaggcttattttcttcacgtgattctgtccaaggatcttcaaaa
ttccagtgccatttgagaggatcagacagcttttttcctctaacctcagaaagagaatat
ataaagtcattagacctttcagcaaatgaactagaggatattgatgggataagcaagaaa
tgctgtttaagtgatcacttaacacgtcttgagaaactagagcttcaccagaatgcactt
acaagaattccacaacaactctgtgaaactttaaaatgtttgaaatacttggacttacac
agtaacaaaatcacttcagttcctgcctatttgtttaaaatgaattgcattgcaaatctt
gatatctcccgtaatgatattggaccttctataattttggatccaactatcagatgtcca
actttgaagcagataaatctctcatacaatcaactatcctctgtccctgaatttcatgca
gatgtcatagaaaatctagaacatctccttctagaaggaaacaaaatatcagaaatatat
tcacctttgtgcttgaaggagttgaagattttaaaccttagtaaaaaccacatatcatcc
ataactgaagatttttttgaggcatgttgcaaactggaagtttttagtgccagaatgaat
ttgctagttgctgtgccttgcttgccctctagcataacaattttaaatttgtcacaaaac
aaatttacatgtattccagaagtaattctcagccttccacatttgcggtcattagatttg
agcagcaatgaaatttacagcctgcctggacctgcacactggaaatcattaaacttacgg
gagcttttgtttaatcataatcagatcagcattttggacttaagtgaaaaagcatatacg
tggtcacggatggagaagctacacttgtcacataataaattaaaggagattcctcctgaa
attggttttcttgaaaatttgacatctcttgatgtgagttacaatttggagctgagatcc
tttcctaatgaaatggggaaattaactaaaatctgggaccttcctttggatgaattgcat
cttaatttcgattttaagcatataggatgcaaggccagagacatcataaggttccttcaa
cagaggttgaagaaggcagtgccctataatcgaatgaaacttatggttgtgggaaatact
ggcagtggaaaaactacgttgttgcaacagttaatgaaatataaaagaacagatttgagc
accccaaatactacaataggcatagatgtaaaagactggtctatccagctaaggaacaaa
gggaagaaagagctgatcctaaatgtctgggatttttcaggacgagaagagttctacagt
gctcaccctcacttcatgacacaacgggcattatatcttgctgtttatgatctcagcaaa
ggacacaccgaaatagatgctatgaagccctggctcttcaacataaaggctcgggcttct
tcctcaccagtgattctggttggtacccatttggatgtttctgatgagaaacggcgaaag
gactccataagcaaaataactaaggagctcttaaacaaaagagtgttccctgaaataagg
gcttaccattttgtgaatgctacagaagaatatgatgcattggtaaaacttcggaaaagt
atcgtaaaagagagtctgaacttcaagatcagagaccagcctgttgtaggacagctaatt
ccagattgctacttggaacttgagaagaaaattttattggagcgaaagaatgttcccatt
gaatttccagtaattagtcagaagcgactggttcagctagtcaaagaaagtcaactacag
ttggatgaaaatgaacttcctcatgcagttcacttcctaaatgaatcaggtgtcctactg
catttccaagacccagcactgcagttaagtgacttgtattttgtggaacctaaatggcta
tgcaaaatgatggcacagattttgacagtgaaagtagaaggctttgctaaatatcctaag
ggcattattcaacgttcggatgtggaaaagttcctttcaaagaagagcagatttcccaag
aactacatgtctcagtactttaaactcttggaaaagtttcagatcgctttaccaatagga
gaagaacatttgctagttccaagcagtttgtctgatcaaagacctgtgatagaacttccc
cactgtgaaaactctgaagttattgttagggtgtatgaaatgccttattttcctatggga
ttttggtccagactgataaatcgattacttgaaatttctccttacatgctttcaggcaga
gaacgggcccttcgccccaacagaatgtattggagacaaggaatctatctgaattggtct
cctgaagcctattgtctggtagaatcttcaattttggacaatagctcagagagttccttg
aaaattacagcaccttcatgcagaaaaggctgtattattttgggacaagttgtagaccac
atagattctctcatggaagaatggtttcctggtttattggaaatagatgtctgtggtgaa
ggagaaacattgttaaagaaatgggctttatacagttttaatgatggtgaagcacagcaa
aaaatattacttgatgatttaatgaagaaaactgaagaaggcgatctcttaatcaatcca
gatgaaccaaggcttactatcccgataggccacattgctcctgatttaattttggccgat
atgcctagaaatatcatgttgaataacgatgagttggaatttaaacaagcaccagaattt
cttttaggtgatggtggttttggatccgtttatcgagcatcctataaaggagaagaagta
gctgtgaagatttttaataaacatacatcacttcgactattaagacaagagctagcagtg
ctttgccatctccaccaccctagcctgatatctttgcttgctgctggaattcgtccccga
atgttggtaatagaattagcctcaaagggttccctagatcagttgctccagcgagacaaa
gctagcttaaccagagcactccagcacaggatagcactccatgttgctgatggcttaagg
tatctccatgaatcgatgattatataccgagatctgaagcctcataatgtactccttttt
accctgtatcctaattctgcaatcattgccaagattgcagattatggaattgctcagtac
tgctgcagaatggggataaagacatctgaaggaacagcaggatttcgtgcacctgaagtt
gccaaaggaaatgtaatttacaaccaacaggctgatatttattcatttggcttattgctt
tatgacattttgactacaggaggtagaattctggaaggattgaaattcccaaatgaattt
gatgagttagctatacacgggagattaccagatccagttaaggaatatggttgtactcca
tggcctaaggtagaaaatttaattaagaagtgtctgaaagaaaatccacaggaaagacca
acatctgcccaggtgtatgaaattttgaactcagctgaattaatatgtctaaggagatat
attttaatacccaaaatatttgtagcagaatgcatggttgccacaaaccaaagcagcaag
aatgcagttatctggctgggtagtgggaacaatgatacaggacaattatcctgtcttgag
ataaatactgaaagacatatctctaaggatatgactgagagtagaatattgtgcctcgcc
cttgtgtatcttctggttgaaaaggaaagctggattgtggcaggaacacaatctggcacc
ctattggcagtgaagacagaagatgataaaaagggccacatgcttcaaagaatgactgac
tctgttacttgtttatactgcaattcgttttctaagcaaagcaaacaaaagaattttctt
ttggttggaactgcaaatggcagactagctatttttgaagacagaaatgttaagtttgaa
ggagctcctcctttgaagacattaaatataggaaatgtcagcactccattaatgtgttta
aatgaatccatatattcatcagaaaaaagtgtaatctggggaggatgtggcaccaagatt
ttctcactttctaatgatttctccattcagaaacttattgagacaaagacaaatcaactg
ttttcttatgcaacgttcagtgatgccaacatcatttcaattgtggtggacaaagctatc
tatgtagctaagaaaaacagccattttgttgaagtatgggataagaacacagagaaactt
tgtgtactaatagactgtgcgcaatttttaaaggaccatacagtaattttaaacaaggaa
tcaaatcataaaatgacttattctggaagagtgaaaaccctctgtctgcagaaaaatact
gcactctggataggtacaggaggaggtcacattttactggtcgatctttcaacacatcgc
atcatacacataattcagaacttttgtaattctattagagcactgatgacagtccagtta
gggagcttaaaaaatgtcatgctggttttggggtactgccagaaaagtaatgaaaacact
ccgactcaaaaagaaatggagtcttgtttgtctatatgggacattaacctaccacatgaa
gtggaaaacttgaagaagcacacagaagttagaagagaattaggtgaaaaaatgagaagt
ttttccatggagtaa
DBGET
integrated database retrieval system
