Pseudoalteromonas sp. Bsw20308: D172_014375
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Entry
D172_014375 CDS
T04175
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pbw
Pseudoalteromonas sp. Bsw20308
Pathway
pbw00260
Glycine, serine and threonine metabolism
pbw00261
Monobactam biosynthesis
pbw00270
Cysteine and methionine metabolism
pbw00300
Lysine biosynthesis
pbw01100
Metabolic pathways
pbw01110
Biosynthesis of secondary metabolites
pbw01120
Microbial metabolism in diverse environments
pbw01230
Biosynthesis of amino acids
Module
pbw_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pbw_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
pbw_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
pbw00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
D172_014375 (thrA)
00270 Cysteine and methionine metabolism
D172_014375 (thrA)
00300 Lysine biosynthesis
D172_014375 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
D172_014375 (thrA)
Enzymes [BR:
pbw01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
D172_014375 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
D172_014375 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
ALQ09133
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All DBs
Position
complement(3249524..3251941)
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AA seq
805 aa
AA seq
DB search
MRVLKFGGSSLADFTCLQQVAQLVKAQLKDEMLLVLSAPGGMTDSLVALASEAEQGLDFS
QQWQALASRCEGLKADVEKSGVVVTSWPDLRGLKNKLDGVSLIQCCPDQVRAFVISFGER
VSVSLMQALLNSQDARYLEATSCIASTGGYIDAEADLVASKARFQAVLKENPATIYIMPG
FTASNDKGELTTLGRNGSDYSAAIAAACLEAEICQIWTDVDGVYSADPRYIKKATKVDFL
SYKEAMELSYFGAKVLHPKTILPCAKAGVPCEIKNTHNPDAQGSLIGNDYSSDEPVKALS
SLQDLAMLTVSGPGMKGKVGMASKVFNALAHDNVSIVLITQSSCEFSISFCVHETDLALA
LDALQTAFELELQAGLIEPVQVQRNLAIVTLVGDNMRAHRGLAAKFFASLAQAQVNIVAI
AQDSTESAISAVIDGELCNDAVKICHENFFTHVPSIDVFLLGCGLVGQELINQLERQQAW
LEKRNIKLNLYGVANSRQLHLDNEGIAFSDWQQKLASSEQAFDLKLVEQFVKQNHLVNPV
LVDCTSSDALAAQYVDFLNAGFHVVAANKKATTSSYTYYQDLIAATQKNNRKFLYETNVG
AGLPVIDNLQSLFGAGDELLEFSGILSGSLSYMFGALQDGLSLSEATIKAKESGFTEPDP
RDDLSGTDVARKLLIIAREAGMKLELCDIEVESVLPQGFAQGDSVDEFMAKLPSLDADFN
DRIQSAASEGKVLRYVGTIKEGHCKVGIEAVDEKHALNVIRDGENALAILSQYYQPRPFV
IRGYGAGSEVTAAGVFADILKTLSR
NT seq
2418 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgttttaaaatttggaggctcgtcgcttgccgactttacttgccttcagcaggta
gctcaattagttaaagcacagctaaaagatgaaatgttattggtgctttctgctccaggt
ggaatgaccgattcattagttgcgttagcaagtgaggcagagcaaggcttagatttttcg
cagcaatggcaagcattagctagccgttgtgaaggcttaaaagctgacgttgaaaaaagt
ggcgtagtagttacaagctggccagacctaaggggacttaaaaataaattagatggcgta
tcgcttatacagtgttgccctgatcaagttcgcgcatttgtaattagttttggagagcgc
gttagtgtttctttaatgcaggctttattgaactcgcaagatgcaagatacttagaagca
acaagctgtatagcttcaacgggtggttacattgatgcagaagcggatttagtggcaagt
aaagcgcgctttcaagctgtgcttaaagaaaaccctgcaactatttatatcatgcctggt
tttacggcgagtaatgataaaggtgagcttacaacgcttggccgtaatggttcagattac
tcagcagctattgctgcggcatgtttagaagctgagatttgccaaatttggactgacgtt
gatggcgtatatagcgctgatcctcgttatattaaaaaagccactaaagtagatttttta
tcttataaagaagcgatggagctttcttactttggtgcaaaagtacttcaccctaaaaca
atcttaccgtgtgctaaagcaggcgtgccatgtgaaattaaaaatacgcataacccagac
gcacaaggctcattaattggtaacgattattcatctgatgagcccgtaaaagcgctttct
agcttacaagaccttgcaatgttaactgtttcaggccctggcatgaaaggtaaagtaggc
atggcgtctaaggtatttaacgcgcttgctcacgataacgtatcaattgtattgatcacg
caatcatcatgtgaatttagcattagtttttgtgtgcacgaaacagacttagcacttgca
ctcgatgcgctacaaactgcatttgagcttgaattacaagcagggcttattgagcctgta
caagtgcagcgcaatttagccattgttactttagtgggtgataacatgcgcgcacaccgt
ggtttagcagctaagttttttgcatcgcttgcacaagcgcaagtaaatattgtggcaatt
gcacaggattctacagaaagtgctatttctgcggtaattgatggtgagttatgtaatgac
gccgtaaaaatatgccatgaaaactttttcacacatgtgccgtcaattgatgtgttttta
ctaggttgtggcttagtagggcaagagcttattaatcagcttgaacgtcaacaagcttgg
cttgaaaagcgtaatattaaactcaacttgtacggtgttgctaactctcgtcaattacac
cttgataacgaaggcattgcttttagtgattggcagcaaaaattagcctcatctgagcaa
gcatttgatttaaagttagtagagcaatttgttaagcaaaaccacttagtgaatccggta
ttagtagattgtacatcttcagatgcacttgctgcgcagtatgtagactttttaaatgca
ggctttcatgtggttgctgccaataaaaaagcaacaacaagctcatacacgtattaccaa
gatttaattgcggcaacacaaaagaataatcgtaaatttttatacgaaacaaatgttggt
gcaggcttaccagtaatcgataacttgcagtcattatttggtgccggtgatgagttatta
gagtttagcggtattttatcaggctcactttcgtatatgtttggcgcacttcaagatggt
ttatcactttctgaggcaactattaaagccaaagaaagcggttttactgagccagaccct
cgtgatgatttatcgggtaccgatgtagcacgtaagttattgatcattgctcgcgaagcc
ggcatgaagttggagctatgcgatatcgaagttgagtcagtattaccacaaggttttgca
caaggtgatagcgttgatgagtttatggcaaaactaccaagcctagatgctgattttaat
gaccgcattcaaagtgctgcgagcgaaggtaaggtacttcgttatgtaggtacaattaaa
gaaggtcactgtaaagtaggtattgaggctgttgatgaaaaacatgcccttaatgtaatt
cgcgatggcgaaaacgcgctggctattttaagccaatactaccagccacgtccgtttgta
attcgtggttatggtgcaggctctgaagtaacagcagcgggtgtatttgctgatatttta
aaaacgttatcgcgctag
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