Syntrophotalea carbinolica: Pcar_2206
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Entry
Pcar_2206 CDS
T00285
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pca
Syntrophotalea carbinolica
Pathway
pca00300
Lysine biosynthesis
pca00550
Peptidoglycan biosynthesis
pca01100
Metabolic pathways
pca01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pca00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Pcar_2206 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Pcar_2206 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Pcar_2206 (murF)
Enzymes [BR:
pca01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Pcar_2206 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABA89445
UniProt:
Q3A2G2
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Position
complement(2578080..2579471)
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AA seq
463 aa
AA seq
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MRLDLTQIMTITGGDLTPERADGVVTGVSTDSRSLRAGDLFVPLRGPRFDGHDFIAQAVQ
SGAVACLSEEVIAGLPVPVIRVTDTLRALGDLAAAVRQAFDGPVVAVTGSSGKTTTKEML
AGILALRGEGLKTEGNFNNLIGLPHTLFRLEADHHWAVLELGMSARGEIARLAEISRPDI
GVITNVGPAHLETLHNLQGVARAKGELFAALPAGGTAVINGDDPRVLQLPVANGVRRLIY
GCGSDAEVRAEDIAVDGHGTHFCLLLAGESWPVHLSVPGRYNVHNALAAAAAAHALKVGG
AQIVEGLEAFRSCAGRMAVAELASGATLLEDFYNANPLAVKAALSALDEMPGSGRRIAVL
GDMLELGDAASEMHRQTGLDASKCVDLLILLGERAEDTAAGARQGGMPPQSVWVVKSHDE
AVQLLAGILRPGDRVLVKGSRGMTMEKICNALRASDGRPSAGH
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atgcgactcgatctgacccaaattatgaccatcaccggtggcgacctgacacccgaacgt
gccgacggtgtcgttaccggagtgtccaccgacagccgctccctgcgtgccggagatctg
ttcgtgccgttgcgcggtccgcgttttgacggtcacgattttatcgcgcaggccgtgcaa
agtggcgcggttgcctgcctgagcgaagaagttattgcaggattgccggtaccggtgatc
cgcgtgaccgataccctgcgggcccttggtgatctggccgctgcggtgcggcaggcgttt
gatgggccggtggtggcggtaaccggctcctccggtaaaaccacgaccaaggagatgctg
gccggtatcttggctttgcggggtgaaggtctcaaaaccgaagggaatttcaataatctg
atcggtctgcctcatacgctttttcgccttgaagccgaccatcattgggcggtgctcgaa
ctcggcatgagcgcccgcggtgaaattgcccggctggcggaaatcagtcggcccgatatc
ggcgttatcaccaacgtgggacctgctcatctggagactttacacaacctgcagggcgtg
gcgcgcgccaaaggcgaactgttcgccgccctgcctgccgggggtacggccgtgatcaac
ggcgacgatcctcgcgttttgcagctgccggtcgccaacggcgtgcgccggcttatttac
ggttgcggttccgatgccgaagtacgtgccgaagacattgccgtggatggacacggaacc
catttttgtctgctattggccggagaaagctggccggttcatttgtcggttcccggtcga
tataacgtgcacaatgccttggccgctgccgccgccgcccatgcattgaaggtaggcggg
gcgcagattgtcgaagggttagaggcctttcgttcttgtgccggtcgtatggccgtggcg
gagcttgccagtggggcgacgttgctggaggacttttacaatgccaatcctctggccgtt
aaggcggccctgtccgcactggacgaaatgcccggtagtggccgccgcatcgctgttttg
ggcgacatgctggagctgggcgatgccgcgtcggaaatgcaccgtcagaccggcctggat
gcttcgaagtgcgtcgatctgttgattctgctcggggaacgggctgaggatacggccgcc
ggtgcacggcagggcggcatgccgccccagtcggtgtgggtggtgaaaagtcacgacgag
gccgtgcagttgctcgcgggaatactgcgacccggcgatcgcgtgttggtcaaaggctct
cgcggcatgaccatggaaaaaatctgtaacgccttgcgcgccagtgatgggcggccatcc
gccggccattag
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