Physeter macrocephalus (sperm whale): 102973776
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Entry
102973776 CDS
T06011
Symbol
CFTR
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad02010
ABC transporters
pcad04024
cAMP signaling pathway
pcad04152
AMPK signaling pathway
pcad04530
Tight junction
pcad04971
Gastric acid secretion
pcad04972
Pancreatic secretion
pcad04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
102973776 (CFTR)
09132 Signal transduction
04024 cAMP signaling pathway
102973776 (CFTR)
04152 AMPK signaling pathway
102973776 (CFTR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
102973776 (CFTR)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
102973776 (CFTR)
04972 Pancreatic secretion
102973776 (CFTR)
04976 Bile secretion
102973776 (CFTR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
pcad02000
]
102973776 (CFTR)
Enzymes [BR:
pcad01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
102973776 (CFTR)
Transporters [BR:
pcad02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
102973776 (CFTR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CFTR_R
ABC_membrane
ABC_tran
SMC_N
AAA_29
AAA_21
T2SSE
AAA_16
DO-GTPase2
RsgA_GTPase
nSTAND3
MeaB
NTPase_1
Zeta_toxin
DUF87
Biotin_lipoyl_2
Intein_splicing
Motif
Other DBs
NCBI-GeneID:
102973776
NCBI-ProteinID:
XP_054940637
Ensembl:
ENSPCTG00005003550
UniProt:
A0A9W2WN89
LinkDB
All DBs
Position
5:complement(32943555..33111100)
Genome browser
AA seq
1480 aa
AA seq
DB search
MCFQSAYVGYWIVSASWTRPILRKGYRQRLELSDIYHISSSDSADNLSEKLEREWDRELA
SKKNPKLINALRRCFFWRFMFYGIILYLGEVTKAVQPLLLGRIIASYDPDNKVERSIAIY
LGIGLCLLFIVRMLLLHPAIFGLHRIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQLVS
LLSNNLNKFDEGLALAHFVWIAPLQVALLMGLLWELLQACAFCGLAFLIVLALLQAGLGK
MMMKYRDQRAGKINERLVITSEMIENIQSVKAYCWEEAMEKIIENLRQTELKLTRKAAYV
RYLNSSAFFFSGFFVVFLSVLPYALLKGIGLRKIFTTISFCIVLRMTVTRQFPWSVQMWY
DSLGAINKIQDFLQKQEYKTLEYNLTTTEVMMENVTAFWEEGFGKLFEKAKQNSNNRKIS
NGDNSLFFSNFSLLGAPVLKDISFKIERGQLLAVSGSTGAGKTSLLMMIMGELEPSEGKI
KHSGRISFCSQFSWIMPGSIKDNIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLG
DGGITLSGGQQARISLARAVYRDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTRIL
VTSKMEHLKKADKILILHEGSSYFYGTFSELQNQRPDFSSKLMGYDTFDQFTAERRNSII
TETLRRFSLEGDTSVSWNETKKQSFKQTGEFGEKRKNSILNSISSTRKFSIVQKTPLQMN
GIEEDSVEPLERRLSLVPSSEPGEAILPQSNMINAGPTFQGRRRQSVLNLMTSSSVNQGQ
SIHRKTGTSTRKMSLAPQANLTEIDIYSRRLSQDTGLEISEEINEEDLRECFFDDVENIP
AVTTWNTYLRYITVHKSLIFVLIWCLVIFLAEVAASLVVLWLFQKTPPQDKGNSTKSANS
SYAVIITSTSSYYVFYIYVGVADTLLALGLFRGLPLVHTVITVSKILHHKMLQSVLQAPM
STLNTLKAGGILNRFSKDIAVLDDLLPLTIFDFIQLLLIVIGAVAVVSVLQPYIFLATMP
VIAAFILLRAYFLCTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKA
LNLHTANWFLYLSTLRWFQMRIEMIFVLFFIAVTFISILTTGEGEGRAGIILTLAMNIMS
TLQWAVNSSIDVDSLMRSVSRVFKFIDMPAEDGKSNKSLKPSKDGQLSKVMIIENQHVKK
DDIWPSGGRMTVKDLTAKYIDGGNAILENISFSISPGQRVGLLGRTGSGKSTLLLAFLRL
LNTEGEIQIDGVSWDSVTLQQWRKAFGVIPQKVFIFYGTFRKNLDPYGQWSDQEIWKVAD
EVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSRAKILLLDEPSAHLDPIT
YQIIRRTLKQAFADCTVILSEHRIEAMLECQRFLVIEENRVRQYDSIQRLLSEKSLFRQA
ISPAVRLKLFPHRNSSKQRSLSKIAALKEETEEEVQETRL
NT seq
4443 nt
NT seq
+upstream
nt +downstream
nt
atgtgcttccaaagtgcttatgttggctactggattgtgagtgccagctggaccagacca
attttgaggaaagggtacagacagcgcctggaattgtcagacatataccatatctcttct
tctgattctgctgacaatctgtctgaaaaattggaaagagaatgggatagagaactggcc
tcaaagaaaaatcccaaactcattaatgcccttcggcgatgctttttctggagatttatg
ttctatggaatcatactatatttaggggaagtcaccaaagcagtacagcctctcttactg
ggaagaatcatagcttcctatgacccagataacaaggtagaacgctccattgcgatttac
ctaggcataggcttatgccttctctttatcgtgaggatgctgctccttcacccagccatt
tttggcctccatcgcattggaatgcagatgagaatagctatgtttagtttgatttataag
aagactttgaagctgtcaagccgtgttctagataaaataagtattggacaacttgttagt
ctcctttccaacaacctgaacaaatttgatgaaggacttgcactggcacacttcgtgtgg
attgctcctttgcaagtggcgctgctgatggggctgctctgggagttgttacaggcctgc
gccttctgtggacttgcttttctcatagtcctggcccttcttcaagccggattagggaaa
atgatgatgaagtacagagatcagagagctggaaagattaatgaaagactggtgatcacg
tcagaaatgattgaaaatatccagtcggttaaggcatactgctgggaagaagcaatggaa
aaaataattgaaaacctaagacaaacagaactgaaactgacgcggaaggcagcctatgtg
agatacctcaatagctcagccttcttcttctcagggttctttgtagtgtttttatctgtg
cttccttatgcactgcttaaaggaatcggccttcgaaaaatattcacaaccatctcattc
tgcatcgttctgcgcatgacagtcactcggcagttcccctggtctgtacaaatgtggtat
gattctcttggagcaataaacaaaatacaggatttcttacaaaagcaagaatataagaca
ctggaatataacttaacaactacagaagtaatgatggagaatgtaacagccttctgggag
gagggatttgggaaattatttgagaaagcaaaacaaaatagtaacaatagaaaaatttcc
aatggtgataacagcctcttcttcagtaacttctcacttctcggtgctcctgtcctgaaa
gatatcagtttcaagatagaaagaggacagttgttggccgtctctggatctactggagca
ggcaagacttcacttctaatgatgattatgggagaactggagccttcagagggtaaaatt
aagcacagtggaagaatttcattctgctctcagttttcctggatcatgcctggcagcatt
aaagataacatcatctttggtgtttcctatgatgagtatagatataggagtgtcatcaaa
gcatgccaactagaagaggacatctccaaatttgcagagaaagacaacatagttcttgga
gatggtggaatcacattgagtggaggtcagcaagcaagaatttctttagcaagagcagta
tacagagatgctgatttgtacctattagactctccttttggatacctagatgtgttaaca
gagaaagaaatatttgaaagctgtgtctgtaaattgatggccaacaaaactaggattttg
gtcacttctaaaatggaacatttaaagaaagctgacaaaatattaattttacatgaaggt
agcagctatttttatgggacattttctgaattacaaaatcaacggcccgacttcagctca
aagctcatgggatatgacacttttgaccagtttactgcagaacgaagaaattcaatcata
actgagactttacggcgtttctcactagaaggagatacttctgtgtcctggaatgaaacg
aaaaagcaatcttttaaacagactggagagtttggtgaaaaaaggaagaactccattctc
aattcaatcagctctacgaggaaattttcaattgtacagaagactccattacaaatgaat
ggcatcgaagaagattctgttgagcctttagaaagaagactatccttagttcccagttct
gaaccgggagaggcgatcctgcctcagagcaacatgatcaatgctggtcccacatttcag
ggacgaaggaggcagtcagtcctgaaccttatgacctcctcctcagtgaaccaaggtcaa
agcattcaccgaaagacagggacatccacacgaaaaatgtcactggcccctcaggcgaac
ttaactgaaatagatatatattcaagacggttatctcaagatactggcttggaaataagt
gaagaaattaatgaagaagatttaagggagtgcttttttgatgatgtggagaacatacca
gcagtgactacatggaacacatacctacgatatattactgtccacaagagcttaattttt
gtgctaatttggtgcttagtcatttttctggctgaggtggctgcttctttggttgtgttg
tggctgtttcaaaaaacacctcctcaagacaaagggaatagtactaagagtgcaaatagc
agttatgcagtgatcatcaccagcaccagctcgtattatgttttttacatttatgtggga
gtagctgacactttgcttgctctgggactcttcagaggtttaccactggtgcatactgta
atcacagtgtcaaaaatactacaccacaaaatgttacagtctgttcttcaagcccctatg
tcaaccctcaacacgttgaaagcaggtgggattcttaatagattctccaaagatatagca
gttttggatgatcttctgcctcttaccatatttgacttcattcagttgttattaattgtg
attggggctgtggcggtagtctcagttttacaaccctacatcttcctagctacaatgcca
gtgatagcggcttttattctattgagagcctacttcctctgcacctcacagcaactcaaa
cagctggaatctgaaggcagaagtccaattttcactcatcttgttacgagcttaaaagga
ctatggacacttcgtgcctttggacggcagccttactttgaaactttgttccacaaagct
ctgaatttacatactgccaactggttcttgtatctatcaacactgcgctggttccaaatg
agaatagaaatgatttttgtcctcttcttcattgctgttaccttcatttccattttaaca
acaggtgaaggagaaggaagagctgggattattctaactttagccatgaatatcatgagt
acactacagtgggctgtaaactctagcatagatgtggatagcttgatgcgatctgtgagc
cgagtctttaagtttattgatatgccagcagaagacgggaaatctaacaagtcgttgaaa
ccatccaaggatggccagctctcgaaagttatgattatcgagaatcaacatgtgaagaaa
gatgacatctggccctcagggggccgaatgactgtcaaagacctcacagcgaagtatata
gacggtgggaatgccatattagagaacatttccttctcaataagtcctggccagagggtg
ggcctcttgggaagaactggatcagggaagagcactttgttactggcttttttgagactg
ctgaacaccgaaggagaaatccaaatagatggtgtgtcttgggattcagtaactttgcaa
cagtggaggaaagcctttggagtcataccacagaaagtattcatcttttatggaacattt
agaaaaaacttggatccttatgggcagtggagtgatcaagaaatatggaaagttgctgat
gaggttggactcagatctgtgatagagcagtttcctgggaagcttgattttgtccttgtg
gatgggggttgtgtcctaagccacggccacaagcagctgatgtgcttggccagatccgtt
ctcagtagagcaaagatcttgctgcttgatgaacccagtgctcatttggatccaataaca
taccaaatcattcgaagaaccctaaaacaagcatttgctgattgcacagtaatcctctct
gaacacaggatagaggcaatgttggaatgtcaacgatttttggtcatagaggagaataga
gtgcggcaatacgactccatccagaggctgctgagcgagaagagcctcttccggcaggcg
atcagccccgcagtccgcttgaagctcttcccccaccggaactcgagcaagcagaggtct
ctgtccaaaatcgctgccctgaaggaggagacggaagaggaggtgcaagaaacaaggctt
tag
DBGET
integrated database retrieval system
