KEGG   Physeter macrocephalus (sperm whale): 102973815
Entry
102973815         CDS       T06011                                 
Symbol
GSTM3
Name
(RefSeq) glutathione S-transferase Mu 3 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad00480  Glutathione metabolism
pcad00980  Metabolism of xenobiotics by cytochrome P450
pcad00982  Drug metabolism - cytochrome P450
pcad00983  Drug metabolism - other enzymes
pcad01100  Metabolic pathways
pcad01524  Platinum drug resistance
pcad05200  Pathways in cancer
pcad05204  Chemical carcinogenesis - DNA adducts
pcad05207  Chemical carcinogenesis - receptor activation
pcad05208  Chemical carcinogenesis - reactive oxygen species
pcad05225  Hepatocellular carcinoma
pcad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    102973815 (GSTM3)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    102973815 (GSTM3)
   00982 Drug metabolism - cytochrome P450
    102973815 (GSTM3)
   00983 Drug metabolism - other enzymes
    102973815 (GSTM3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102973815 (GSTM3)
   05204 Chemical carcinogenesis - DNA adducts
    102973815 (GSTM3)
   05207 Chemical carcinogenesis - receptor activation
    102973815 (GSTM3)
   05208 Chemical carcinogenesis - reactive oxygen species
    102973815 (GSTM3)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    102973815 (GSTM3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    102973815 (GSTM3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    102973815 (GSTM3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:pcad02000]
    102973815 (GSTM3)
Enzymes [BR:pcad01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     102973815 (GSTM3)
Transporters [BR:pcad02000]
 Other transporters
  Pores ion channels [TC:1]
   102973815 (GSTM3)
SSDB
Motif
Pfam: GST_C GST_C_3 GST_N GST_N_3 GST_N_2 GST_C_6
Other DBs
NCBI-GeneID: 102973815
NCBI-ProteinID: XP_007106539
Ensembl: ENSPCTG00005014370
UniProt: A0A2Y9EPD0
LinkDB
Position
Unknown
AA seq 225 aa
MSLKSTMVLGYWDIRGLAHPIRMLLEFTDTAYEEKRYTCGEAPDYDKSQWLDMKFKLDLD
FPNLPYLMDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDMMENQIMDFRMQLTQLCY
NPDHEKLKPQYLEQLPGQLKQFSLFLGKYSWFAGEKLTYVDFLTYDVLDQNHIFEPKCLD
EFPNLKAFMCRFEALEKIAAYMQSDRFFKMPINNKMAQWGNKRIC
NT seq 678 nt   +upstreamnt  +downstreamnt
atgtcgttgaagtcgaccatggttctgggttactgggatattcgcgggctggcgcatccc
atccgcatgctcctggagttcacggatacagcctatgaagagaaaagatacacgtgcggg
gaagctcctgactatgataaaagccagtggctggatatgaaattcaaactagacctggat
tttcctaacctgccctatctcatggacggtaagaacaagatcacccagagcaatgccatc
ttgcgctatatcgcccgcaagcacaatatgtgtggtgagactgaagaagaaaagattcga
gtggacatgatggagaaccaaataatggattttcgcatgcaactgacacaactctgctac
aaccctgaccacgaaaaactgaagcctcagtacttggaacagctacctggacagctgaaa
cagttctccttgttcctggggaaatactcatggtttgcaggggaaaagctcacctatgtg
gatttcctcacctatgatgtgttagatcagaaccatatctttgagcccaagtgcctggat
gaatttccaaatctgaaggctttcatgtgccgttttgaggccttggagaaaatagctgcc
tacatgcagtctgaccgcttctttaagatgcccatcaacaacaagatggcccagtggggc
aacaagagaatatgctga

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