KEGG   Physeter macrocephalus (sperm whale): 102974757
Entry
102974757         CDS       T06011                                 
Symbol
GCK
Name
(RefSeq) LOW QUALITY PROTEIN: hexokinase-4
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad00010  Glycolysis / Gluconeogenesis
pcad00052  Galactose metabolism
pcad00500  Starch and sucrose metabolism
pcad00520  Amino sugar and nucleotide sugar metabolism
pcad00524  Neomycin, kanamycin and gentamicin biosynthesis
pcad01100  Metabolic pathways
pcad01200  Carbon metabolism
pcad01250  Biosynthesis of nucleotide sugars
pcad04910  Insulin signaling pathway
pcad04911  Insulin secretion
pcad04917  Prolactin signaling pathway
pcad04922  Glucagon signaling pathway
pcad04930  Type II diabetes mellitus
pcad04950  Maturity onset diabetes of the young
pcad05230  Central carbon metabolism in cancer
Module
pcad_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
pcad_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    102974757 (GCK)
   00052 Galactose metabolism
    102974757 (GCK)
   00500 Starch and sucrose metabolism
    102974757 (GCK)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    102974757 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    102974757 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    102974757 (GCK)
   04910 Insulin signaling pathway
    102974757 (GCK)
   04922 Glucagon signaling pathway
    102974757 (GCK)
   04917 Prolactin signaling pathway
    102974757 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    102974757 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102974757 (GCK)
   04950 Maturity onset diabetes of the young
    102974757 (GCK)
Enzymes [BR:pcad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     102974757 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 102974757
NCBI-ProteinID: XP_007125007
Ensembl: ENSPCTG00005005671
UniProt: A0A2Y9FJL4
LinkDB
Position
5:complement(99778073..99788631)
AA seq 537 aa
MLCPRHQPVLTLCSAGPALGPSGSLWPQEAGFLHLTMRNWFPTVIWGTPSPILSLGHFPR
SSGGPWAGGNFSPRQGIPADSPSSPLPFPQFILGSPRCLASGAPRPALLVPPPCLPLLLS
QSWGLLPRGAHETDVLLSVAAEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMY
SIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWT
KGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGT
GCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQL
YEKLIGGKYMGELVRLVLLKLVDENLLFHGEASEKLRTRGAFETRFVSQVESDSGDRKQI
YNILSTLGLRPSATDCDIVRRACESVSTRAARMCAAGLAGVINRMRESRSEDVMRITVGV
DGSVYKLHPSFKERFHAGVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgctgtgccccagacaccagccagttctcaccctctgctccgctggcccagccctgggg
ccttcaggctcactctggcctcaggaagctggctttcttcatctcacaatgagaaactgg
tttcccacagtcatttgggggactcccagcccaatcttgagtctgggccattttcctagg
tcttcaggtgggccctgggctgggggcaacttcagcccaaggcaagggattcctgctgac
tcccccagttcacctttgccctttccacagtttatcctggggtcccccagatgtctggca
tcaggggcccctcgtccagctcttctggttcccccaccatgccttcccctcctcctctcc
cagtcttgggggctcctaccacgcggtgcccatgagactgatgtgcttctctctgtggct
gcagaagtcggggacttcctctccctggacctgggcggcaccaacttcagggtgatgctt
gtgaaggtgggggaaggggaggagggacagtggagtgtgaaaaccaagcaccagatgtac
tccatccccgaggacgccatgacgggcactgctgagatgctctttgactacatctctgag
tgcatctccgacttcctggacaagcatcagatgaagcacaagaagctgcccctgggcttc
accttctcctttcctgtgaggcatgaagacatcgacaagggcatccttctcaactggacc
aagggcttcaaggcctcaggagcagaagggaacaacatcgtggggctcctgcgagatgcc
atcaaacggagaggggactttgagatggacgtggtggcgatggtgaacgacactgtggcc
acgatgatctcctgctactatgaagaccgccggtgtgaggttggcatgattgtgggcacg
ggctgcaacgcctgctacatggaggagatgcagaacgtggagctggtggaaggggacgag
ggccgcatgtgtgtcaacaccgagtggggtgccttcggggactcgggcgagctggacgag
ttcctgctggagtacgaccgtgtggtggacgagaactccctgaaccccggccagcagctg
tacgagaagctcatcggcggcaagtacatgggcgagctggtgcgcctcgtgctgctgaag
cttgtggacgagaacctgctcttccacggggaggcctcggagaagctgcgcacgcgcggc
gccttcgagacacgcttcgtgtcgcaggtggagagtgactcgggcgaccgcaagcagatc
tacaacatcctgagcacgctggggctgaggccctcggccaccgactgcgacatcgtgcgc
cgcgcctgcgagagcgtgtccacccgcgccgcgcgcatgtgcgccgcggggctggcgggc
gtcatcaaccgcatgcgcgagagccgcagcgaggacgtgatgcgcatcaccgtgggcgtg
gacggctcagtgtacaagctgcaccccagcttcaaggagcggttccacgccggcgtgcgc
aggctgacgcccagctgtgaaatcaccttcatcgagtcggaggagggcagcggccggggt
gcggccttgatctccgcggtggcctgtaagaaggcctgcatgctgggccagtga

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