Physeter macrocephalus (sperm whale): 102975788
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Entry
102975788 CDS
T06011
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X2
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00260
Glycine, serine and threonine metabolism
pcad00630
Glyoxylate and dicarboxylate metabolism
pcad00670
One carbon pool by folate
pcad01100
Metabolic pathways
pcad01200
Carbon metabolism
pcad01230
Biosynthesis of amino acids
pcad01240
Biosynthesis of cofactors
pcad01523
Antifolate resistance
pcad04981
Folate transport and metabolism
Module
pcad_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
102975788 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
102975788 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
102975788 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102975788 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102975788 (SHMT1)
Enzymes [BR:
pcad01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
102975788 (SHMT1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
102975788
NCBI-ProteinID:
XP_023983467
Ensembl:
ENSPCTG00005006184
UniProt:
A0A2Y9T1R1
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All DBs
Position
14:complement(81987554..82012887)
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AA seq
484 aa
AA seq
DB search
MATPVNGAPMDANLWSSHEKMLAQPLKESDVEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEVLCQKRALQVYGLDPQGWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTNKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLREIADDNGAYLMADMAHVSGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGRETRYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRVYQRQVLANCRALAEALMGLGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGSPALTSRGLSEEDFQK
VAHFIHRGIELTLQIQDTVGAKATLKEFTEKLAGAEDHQRAVAALRAEVESFAALFPLPG
LPDV
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcgactcccgtcaacggagcccccatggatgccaacttgtggtcctcacatgagaag
atgctggcgcagcccctgaaagagagtgacgtggaggtttacaacatcattaagaaggag
agtaaccggcagagggtcggactggagctgatcgcctcagagaactttgccagccgggct
gttctggaggccctaggttcttgcctaaacaacaagtactccgaggggtacccgggccaa
aggtactacggcgggacggaattcatcgatgagctggaggtcctctgtcagaagcgagcg
ctgcaggtctatggcctggacccccagggttggggagtcaatgtccaaccctactcaggc
tcccccgcaaacttcgcggtgtacacagccctggtggagccccatggccgcatcatgggc
ctggacctgcccgacgggggccacctgacccacgggttcatgaccaacaagaagaagatc
tccgctacgtccatctttttcgaatctatgccctacaaggtgaaccccgacaccggctac
atcaactacgaccagctggaggagaacgcgcgcctcttccacccgaagctcatcatcgca
gggaccagctgctactcccggaacctggactacgcccggctgcgcgaaatcgctgacgac
aacggggcgtatctcatggccgacatggcgcacgtcagcgggctggtggcggccggcgtg
gtgccctcccccttcgagcactgccacgtggtgtccaccaccacccacaagaccctgcgg
ggctgccgcgccggcatgatcttctacaggaagggagtgcgcagcgtggacccgaagacg
ggcagagagactcgctacaacctggagtcactcatcaactctgccgtgttcccaggcctg
cagggggggccccacaaccacgccattgctggggtggcggtggctctgaagcaggccatg
actccggagttcagagtctaccagcgccaggtgctggccaactgcagggctctggccgag
gccttgatggggctgggctacaaagtggtcacaggtggttctgacaaccacttgatcctc
gtggacctccgctccaaaggcacggacggcggccgggctgagaaggtgctggaagcctgt
tccatcgcctgcaacaagaacacctgcccaggtgacaaaagcgccctgcggcccagcgga
ctgcgcctggggagcccggcgctgacatcccgaggactctcggaggaagatttccagaaa
gtcgcccattttattcacagagggatagagctgaccctgcagatccaggacaccgtgggg
gcgaaggccaccctgaaggagttcacggagaagctggcgggggccgaggatcaccagcgg
gctgtggcggcactccgggcggaggtggagagcttcgccgccctcttccctctgcctggc
ctgcccgacgtctag
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