KEGG   Physeter macrocephalus (sperm whale): 102975968
Entry
102975968         CDS       T06011                                 
Symbol
EIF2S1
Name
(RefSeq) eukaryotic translation initiation factor 2 subunit 1
  KO
K03237  translation initiation factor 2 subunit 1
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad04137  Mitophagy - animal
pcad04140  Autophagy - animal
pcad04141  Protein processing in endoplasmic reticulum
pcad04210  Apoptosis
pcad04932  Non-alcoholic fatty liver disease
pcad05010  Alzheimer disease
pcad05012  Parkinson disease
pcad05014  Amyotrophic lateral sclerosis
pcad05020  Prion disease
pcad05022  Pathways of neurodegeneration - multiple diseases
pcad05160  Hepatitis C
pcad05162  Measles
pcad05164  Influenza A
pcad05168  Herpes simplex virus 1 infection
pcad05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102975968 (EIF2S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102975968 (EIF2S1)
   04137 Mitophagy - animal
    102975968 (EIF2S1)
  09143 Cell growth and death
   04210 Apoptosis
    102975968 (EIF2S1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    102975968 (EIF2S1)
   05164 Influenza A
    102975968 (EIF2S1)
   05162 Measles
    102975968 (EIF2S1)
   05168 Herpes simplex virus 1 infection
    102975968 (EIF2S1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102975968 (EIF2S1)
   05012 Parkinson disease
    102975968 (EIF2S1)
   05014 Amyotrophic lateral sclerosis
    102975968 (EIF2S1)
   05020 Prion disease
    102975968 (EIF2S1)
   05022 Pathways of neurodegeneration - multiple diseases
    102975968 (EIF2S1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102975968 (EIF2S1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102975968 (EIF2S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:pcad03012]
    102975968 (EIF2S1)
   04131 Membrane trafficking [BR:pcad04131]
    102975968 (EIF2S1)
Translation factors [BR:pcad03012]
 Eukaryotic type
  Initiation factors
   eIF-2
    102975968 (EIF2S1)
Membrane trafficking [BR:pcad04131]
 Autophagy
  ER-phagy
   ER stress-related proteins
    102975968 (EIF2S1)
SSDB
Motif
Pfam: EIF_2_alpha S1
Other DBs
NCBI-GeneID: 102975968
NCBI-ProteinID: XP_007115502
Ensembl: ENSPCTG00005014287
UniProt: A0A2Y9F653
LinkDB
Position
11:148322776..148342655
AA seq 315 aa
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN
KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE
YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDGLDLNEDEREVLINNI
NRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTT
TLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEV
DGDDDAEEMEAKAED
NT seq 948 nt   +upstreamnt  +downstreamnt
atgccgggtctaagttgtagattttatcagcacaaatttcctgaggtggaagacgtagtg
atggtgaatgtaaggtccattgctgaaatgggagcttatgtcagcttgctggaatacaac
aacatcgaaggcatgattcttctgagtgagttgtccagaaggcgtatccgttctataaac
aaactcatccgaattggcaggaatgaatgtgtggttgttatcagagtggacaaagaaaaa
ggatatattgatttgtcaaaaagaagagtttctccagaggaagcaatcaaatgtgaagat
aaatttaccaaatccaaaactgtttacagcattcttcgtcatgttgctgaggtcttagaa
tataccaaggatgagcagctggaaagcctgttccagaggaccgcttgggtcttcgatgac
aagtacaagagacccggatatggtgcctatgatgcatttaagcacgcagtctcagaccca
tctattttggatggcttagatttgaatgaagatgaacgggaagtactcattaacaatatt
aatagacgtttgactccacaggctgtcaaaattcgagcagacattgaagtggcttgttat
ggttatgaaggcattgatgctgtaaaagaagccctgagagcaggtttgaattgttctaca
gaaaccatgcccatcaagattaatctaatagctcctcctcggtatgtaatgactacaacc
accctggagagaacagaaggcctctctgtcctcaaccaagctatggctgttataaaagaa
aagattgaggaaaagaggggcgtcttcaatgttcaaatggagcccaaagtggtcacagat
acagatgagactgaacttgcaaggcagctggagaggcttgagagagaaaatgccgaagtg
gatggagatgatgatgcagaagaaatggaagccaaagccgaagattaa

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