Physeter macrocephalus (sperm whale): 102976068
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Entry
102976068 CDS
T06011
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad04010
MAPK signaling pathway
pcad04020
Calcium signaling pathway
pcad04022
cGMP-PKG signaling pathway
pcad04024
cAMP signaling pathway
pcad04218
Cellular senescence
pcad04260
Cardiac muscle contraction
pcad04261
Adrenergic signaling in cardiomyocytes
pcad04270
Vascular smooth muscle contraction
pcad04530
Tight junction
pcad04713
Circadian entrainment
pcad04723
Retrograde endocannabinoid signaling
pcad04724
Glutamatergic synapse
pcad04725
Cholinergic synapse
pcad04726
Serotonergic synapse
pcad04727
GABAergic synapse
pcad04728
Dopaminergic synapse
pcad04911
Insulin secretion
pcad04912
GnRH signaling pathway
pcad04921
Oxytocin signaling pathway
pcad04924
Renin secretion
pcad04925
Aldosterone synthesis and secretion
pcad04927
Cortisol synthesis and secretion
pcad04929
GnRH secretion
pcad04930
Type II diabetes mellitus
pcad04934
Cushing syndrome
pcad04935
Growth hormone synthesis, secretion and action
pcad04973
Carbohydrate digestion and absorption
pcad05010
Alzheimer disease
pcad05020
Prion disease
pcad05022
Pathways of neurodegeneration - multiple diseases
pcad05031
Amphetamine addiction
pcad05207
Chemical carcinogenesis - receptor activation
pcad05410
Hypertrophic cardiomyopathy
pcad05412
Arrhythmogenic right ventricular cardiomyopathy
pcad05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102976068 (CACNA1D)
04020 Calcium signaling pathway
102976068 (CACNA1D)
04024 cAMP signaling pathway
102976068 (CACNA1D)
04022 cGMP-PKG signaling pathway
102976068 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
102976068 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
102976068 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
102976068 (CACNA1D)
04929 GnRH secretion
102976068 (CACNA1D)
04912 GnRH signaling pathway
102976068 (CACNA1D)
04921 Oxytocin signaling pathway
102976068 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
102976068 (CACNA1D)
04924 Renin secretion
102976068 (CACNA1D)
04925 Aldosterone synthesis and secretion
102976068 (CACNA1D)
04927 Cortisol synthesis and secretion
102976068 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
102976068 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
102976068 (CACNA1D)
04270 Vascular smooth muscle contraction
102976068 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
102976068 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
102976068 (CACNA1D)
04727 GABAergic synapse
102976068 (CACNA1D)
04725 Cholinergic synapse
102976068 (CACNA1D)
04728 Dopaminergic synapse
102976068 (CACNA1D)
04726 Serotonergic synapse
102976068 (CACNA1D)
04723 Retrograde endocannabinoid signaling
102976068 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
102976068 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
102976068 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
102976068 (CACNA1D)
05020 Prion disease
102976068 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
102976068 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
102976068 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
102976068 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
102976068 (CACNA1D)
05414 Dilated cardiomyopathy
102976068 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102976068 (CACNA1D)
04934 Cushing syndrome
102976068 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pcad04040
]
102976068 (CACNA1D)
Ion channels [BR:
pcad04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
102976068 (CACNA1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
102976068
NCBI-ProteinID:
XP_023979576
Ensembl:
ENSPCTG00005022339
UniProt:
A0A2Y9SLQ4
LinkDB
All DBs
Position
18:complement(39775674..40107157)
Genome browser
AA seq
2183 aa
AA seq
DB search
MMMMMMMKKMQHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPAPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSGGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLRGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GEGENQGCCGSLWCWWRRRGATKAGPSGCRRWGQAISKSKLSRRWRRWNRFSRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREDDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNIKEKITPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGEVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGP
IYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIVDVALSEADPTESENVPVP
TATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAML
FFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKL
CDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPH
HLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNS
DGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDE
VTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNSTIALQAGLRTLHDIGPEIRRAISC
DLQDDEPEETKGEEEEDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSMPP
ASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPSSTNANLNNANMSKAAPGKRPSIGNLEHV
SENGHHSFHKHGREPQRRSSIKRTRYYETYIRSDSGDEQFPTICREDPEIHGYFRDPCCL
GEQEYFSSEECYEDDSSPTGSRQSYSCGYYTRYPGSSLDFERPRGYHHPQSFSEDDDSPV
CYDPRRSPRRRLLPPTPTSPRRSSFNFECLRRHSSQEEVPPSPAFPHRTALPLHLMQQQI
MAVAGLDSSKAQKYSPSHSTRSWATPPATPSYRDWTPYYTPLIQVERSEAPDQVNGSLPS
LHRSSWYTDEPGVSYRTFTPASLTVPSSFHNKNSDKQRSADSLVEAVLISEGLGRYARDP
KFVSATKHEIADACDLTIDEMESAASNLLNGNVHPRANGDVGPVSHRQDYELQDFGPGYS
DEEPDPGRDEEDLADEMICITTL
NT seq
6552 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccaggctccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctgtcttggcaagccgcgattgacgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccgcacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgaaacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcggtaaccactccggtggcaaatcgggaggctttgatgtcaaagccctccgc
gcctttcgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtc
ctgaactccatcataaaagccatggttcccctccttcacatagcccttttggtgttattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaggaggacccagcaccgtgtgcgttctca
gggaatggacgccagtgtaccgccaatggcacagagtgtaggagtggctgggttggcccc
aatggcggcatcaccaactttgataactttgcctttgccatgctcaccgtgtttcagtgc
atcaccatggagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaggaaagggagaaggcgaaagcacgggga
gacttccagaagctgcgggagaagcagcagctggaggaggacctcaggggctacttggat
tggatcacccaagcagaagatattgatcccgagaacgaagaagaaggaggagaggaaagc
aaacgaaacaccagcatgcccaccagtgagacggagtctgtgaacacggagaacgtgagt
ggggaaggcgagaaccaaggttgctgtgggagcctctggtgctggtggagaagaagaggc
gccaccaaggccgggccctctgggtgtcggcggtggggtcaagccatctcaaaatccaag
ctcagccgacgctggcgccgctggaaccgcttcagtcgcagaaggtgtagggctgccgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctctgagcactacaaccagcctgactggttgacacagattcaagatatcgctaacaaa
gtcctcttggctctgttcacctgcgagatgcttgtaaagatgtacagcttgggtctccag
gcatatttcgtctctcttttcaatcggtttgattgcttcgtggtgtgtggaggaatcact
gaaacgatcttggtggaactggaaatcatgtctcctctgggcatctctgtgtttcgctgt
gttcggctcttgagaattttcaaagtgaccaggcactggacctccctgagcaacttggtg
gcgtccttgttgaactccatgaagtccatcgcttcgctgctgcttctgcttttcctcttc
atcatcatcttttccttgctggggatgcagctgttcggcggcaagtttaattttgacgaa
acgcaaaccaagcggagcacctttgataatttccctcaagcgctcctaacggtgttccag
attctgacaggtgaagactggaatgctgtgatgtatgatggcattatggcgtacgggggc
ccgtcgtcttcgggaatgatcgtctgcatctacttcatcatcctcttcatttgcggtaac
tatattctactgaatgtcttcttggccatcgctgtagacaacttggctgatgctgaaagt
ttgaatactgctcagaaagaggaagctgaagaaaaggaaagaaagaagattgccagaaaa
gaaagcctggaaaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgac
aacaaggtcaccatcgatgactaccgagaagacgatgaggacaaggacccctacccgcct
tgtgacgtgccagtaggtgaagaggaagaggaggaggaagaggatgaacccgaggttcct
gcgggcccccgtcctcgaagaatctctgagttgaacatcaaagagaaaatcacccccatc
cccgaagggagcgctttcttcattcttagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacatcttcaccaaccttatcctcgtcttcatcatgctgagcagc
gctgccctcgccgccgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctgttaaagatgacgact
tttggagctttcctccacaaaggggctttctgcaggaactacttcaacttactggatatg
ctggtcgttggggtgtctctggtgtcatttgggatccaatccagtgccatctctgttgtg
aagatcctgagagtcttaagggtcctgagaccgctcagggcaatcaacagagcaaaagga
cttaagcacgtggtccagtgcgtctttgtggccatccggacaattggcaacatcatgatc
gtcaccaccctcctccagttcatgtttgcctgcatcggggtgcagctcttcaagggaaag
ttttatcgatgcacagatgaagccaaaagtaaccccgaagaatgcagggggctcttcatc
ctctacaaggatggggaggtcgataaccctgtggtccgtgagaggatctggcaaaacagc
gatttcaactttgacaacgtcctctcagctatgatggctctgttcacggtctccacgttc
gagggctggcccgcgttgctgtacaaagccatcgactcgaacggagagaacgtcggcccc
atctacaactaccgcgtggagatctccatcttcttcatcatctacatcatcatcgtagca
ttcttcatgatgaacatctttgtgggcttcgtcatcgtcacatttcaggagcagggcgag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttg
aaagcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactacgagcagtccaagatgtttaatgacgccatggacatcctg
aacatggtcttcaccggggtgttcactgtcgagatggttttgaaagtcattgcatttaaa
cctaaggggtactttagtgatgcctggaacacgtttgactccctcatcgtaatcggcagc
attgtagacgtggcgctcagcgaagccgacccaactgaaagtgaaaatgtccctgtccca
actgctacacctgggaactctgaagagagcaatagaatctccatcacctttttccgtctt
ttccgagtgatgcgattggtgaagcttctcagcaggggggaaggcatccggacactgctg
tggacttttattaagtccttccaggcgctcccgtacgtcgcccttctcatcgccatgctg
ttcttcatctacgcggttatcggcatgcagatgtttgggaaagttgccatgagagataac
aaccagatcaacaggaacaacaatttccagacctttccccaggcagtgctgctgctcttc
aggtgtgcgacgggggaggcctggcaggaaatcatgctggcctgcctcccgggaaagctc
tgtgaccccgagtccgattacaaccccggggaggagtacacctgtgggagcaactttgcc
attgtttatttcatcagtttttacatgctctgcgcatttctgatcatcaacctgtttgtg
gccgtcatcatggacaatttcgattatctgacccgggactggtctattctggggcctcac
catttagacgaattcaaaaggatatggtccgaatatgaccccgaggcaaagggaagaatc
aagcacctggacgtggtcactcttctccgccgcatccagcccccgctggggtttgggaaa
ttgtgtccacacagggtagcctgcaagagactagttgccatgaacatgccgctcaacagt
gatgggacagtcatgtttaacgcaactctgtttgctttggtccgaacggctcttaaaatc
aagacggaagggaacctggaacaagctaatgaagaactccgagctgtgattaagaaaatc
tggaagaaaaccagcatgaaactacttgaccaagttgtccctccagctggtgatgatgag
gtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaag
aaacggaaagaacaaggactggtgggaaaataccccgcgaagaacagcacaattgcccta
caggcgggattaaggacactgcacgacattgggccagaaatccggcgtgctatatcatgt
gatttgcaagatgatgagccagaggaaacaaaaggcgaagaagaagaagatgtgttcaaa
agaaatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagattcc
cttcagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcaatgccacct
gcaagtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccat
cataaccataattccataggaaagcaagttcccagctcaacaaatgccaatctcaataat
gccaatatgtccaaagctgcccctggaaaacggcccagcattgggaaccttgagcatgtg
tctgaaaatgggcatcattccttccacaagcatggccgtgagcctcaaagaaggtccagt
attaaaagaacccgctattatgaaacttatattaggtctgactcaggagacgagcagttc
ccaactatttgccgggaagacccagagatacacggctacttcagggacccctgctgcttg
ggggagcaggagtacttcagcagtgaggagtgctacgaggacgacagctcgcccaccggg
agcaggcaaagctacagctgtggctactatacccgatacccaggcagcagcttggacttc
gagcggcctcgaggctaccatcacccccaaagcttctcggaggatgatgactcacctgtt
tgctatgatccccggaggtctccaaggagacgcctgctccctcccaccccaacatcgccc
cggagatcctccttcaacttcgagtgcctgcgccggcacagcagccaggaggaggtcccg
ccgtcccccgccttcccccaccgcacggccctgcctctgcacctgatgcagcaacagatc
atggcagtcgccggcctagattccagtaaagcccagaagtactcgccaagccactccacc
cggtcgtgggccaccccgccagcgaccccgtcgtacagggactggacgccgtactacacc
ccgctgatccaggtcgagcggtcggaggccccggaccaggtcaacggcagcctaccgtcc
ctgcaccgcagctcgtggtacacggacgagcccggcgtctcctatcggacgttcacacca
gccagcctgaccgtccccagcagcttccacaacaaaaacagcgacaagcagaggagcgca
gacagcttggtggaggcggttctgatatccgaaggcttaggacggtatgcgagggaccca
aaattcgtgtcagcgacaaaacacgaaatcgccgatgcctgtgacctaaccatcgacgag
atggagagtgcagccagcaacctgctgaacgggaacgtgcacccgcgggccaatggggac
gtggggcccgtctcccatcggcaagactacgagctccaggacttcgggcccggctacagc
gacgaggagccagaccccgggcgggatgaggaggacctggcagatgaaatgatttgcatc
accaccctgtag
DBGET
integrated database retrieval system
