KEGG   Physeter macrocephalus (sperm whale): 102978137
Entry
102978137         CDS       T06011                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad04120  Ubiquitin mediated proteolysis
pcad04380  Osteoclast differentiation
pcad04630  JAK-STAT signaling pathway
pcad04668  TNF signaling pathway
pcad04910  Insulin signaling pathway
pcad04917  Prolactin signaling pathway
pcad04920  Adipocytokine signaling pathway
pcad04930  Type II diabetes mellitus
pcad04931  Insulin resistance
pcad04932  Non-alcoholic fatty liver disease
pcad04935  Growth hormone synthesis, secretion and action
pcad05160  Hepatitis C
pcad05164  Influenza A
pcad05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    102978137 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    102978137 (SOCS3)
   04668 TNF signaling pathway
    102978137 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102978137 (SOCS3)
   04920 Adipocytokine signaling pathway
    102978137 (SOCS3)
   04917 Prolactin signaling pathway
    102978137 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    102978137 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102978137 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    102978137 (SOCS3)
   05164 Influenza A
    102978137 (SOCS3)
   05168 Herpes simplex virus 1 infection
    102978137 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102978137 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    102978137 (SOCS3)
   04931 Insulin resistance
    102978137 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:pcad04121]
    102978137 (SOCS3)
Ubiquitin system [BR:pcad04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     102978137 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 102978137
NCBI-ProteinID: XP_023985784
Ensembl: ENSPCTG00005022423
UniProt: A0A2Y9TCK0
LinkDB
Position
14:125071370..125077389
AA seq 229 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
STEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPSGAPSFSSPPTEPSSSPSSEVPEQPSAQPLPGSPPRRAYYIYSGGEKIPL
VLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 690 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttctactggagcgcggtgacgggcggcgaggcgaacctgctgctc
agcaccgagcccgccggcaccttcctcatacgcgacagctcggatcagcgccacttcttc
acgctcagcgtcaagacgcagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttctcgctgcagagcgatcctcggagcacgcagccagtgccccgcttcgactgcgtg
ctcaagctggtgcatcactacatgccgccctccggcgccccctccttctcctcgccccca
accgaaccctcctcctcgccctcctccgaggtgcccgagcagccgtcggcccagccgctc
ccggggagcccccccaggagagcctattacatctactcggggggtgagaagatccctctg
gtgttgagccggcccctctcctccaacgtggccactctccaacatctctgtcggaagacc
gttaacggccacctggactcctatgagaaagtcacccagctgcctgggcccattcgggag
ttcctggaccagtacgatgcccccctttag

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