Physeter macrocephalus (sperm whale): 102978811
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Entry
102978811 CDS
T06011
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad04062
Chemokine signaling pathway
pcad04081
Hormone signaling
pcad04148
Efferocytosis
pcad04151
PI3K-Akt signaling pathway
pcad04217
Necroptosis
pcad04550
Signaling pathways regulating pluripotency of stem cells
pcad04630
JAK-STAT signaling pathway
pcad04658
Th1 and Th2 cell differentiation
pcad04659
Th17 cell differentiation
pcad04725
Cholinergic synapse
pcad04917
Prolactin signaling pathway
pcad04920
Adipocytokine signaling pathway
pcad04933
AGE-RAGE signaling pathway in diabetic complications
pcad04935
Growth hormone synthesis, secretion and action
pcad05140
Leishmaniasis
pcad05145
Toxoplasmosis
pcad05152
Tuberculosis
pcad05161
Hepatitis B
pcad05164
Influenza A
pcad05167
Kaposi sarcoma-associated herpesvirus infection
pcad05168
Herpes simplex virus 1 infection
pcad05200
Pathways in cancer
pcad05207
Chemical carcinogenesis - receptor activation
pcad05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pcad05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102978811 (JAK2)
04151 PI3K-Akt signaling pathway
102978811 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
102978811 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
102978811 (JAK2)
09143 Cell growth and death
04217 Necroptosis
102978811 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102978811 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
102978811 (JAK2)
04659 Th17 cell differentiation
102978811 (JAK2)
04062 Chemokine signaling pathway
102978811 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
102978811 (JAK2)
04917 Prolactin signaling pathway
102978811 (JAK2)
04935 Growth hormone synthesis, secretion and action
102978811 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
102978811 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102978811 (JAK2)
05207 Chemical carcinogenesis - receptor activation
102978811 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102978811 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
102978811 (JAK2)
05164 Influenza A
102978811 (JAK2)
05168 Herpes simplex virus 1 infection
102978811 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
102978811 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
102978811 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102978811 (JAK2)
05140 Leishmaniasis
102978811 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102978811 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
102978811 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102978811 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102978811 (JAK2)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102978811 (JAK2)
Protein kinases [BR:
pcad01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102978811 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
102978811
NCBI-ProteinID:
XP_023982539
Ensembl:
ENSPCTG00005005720
UniProt:
A0A2Y9SYZ0
LinkDB
All DBs
Position
9:47944767..48113040
Genome browser
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSSSPVHQNGDIPGNANSVKQIDPVLQVYLYHSLGKAEGDYLKFPTG
EYVAEEICVAASKACGITPVYHSMFALMNETERIWYPPNHVFHLDESTRHNVLYRVRFYF
PYWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLDIYSSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVSIKQANQEGSNESRIITIHKQDGKSLEIELRSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKI
RNEDLIFHESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDIYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKTLIHGNVCTKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYENRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQGKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEMYVIMTECWNNNVNQRPSFRDLALRVDQIRDSMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcatgccttacaatgacagaaatggaaggaacatcctcatctcctgtacat
cagaacggtgatattcctggaaatgctaattctgtgaagcagatagatccagttctacag
gtctatctttatcattcccttggaaaagccgagggggattatctgaagtttccaactggg
gagtatgttgcagaagagatttgtgttgctgcttctaaagcttgtggaatcacacctgtg
tatcatagtatgtttgctttaatgaatgaaacagaaaggatctggtatccacccaaccac
gtcttccatttagatgaatcaaccaggcacaatgtactctacagagtcagattttacttt
ccttactggtattgtaatggcagcaacagaacctataggcatggaatatctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgat
tttttgcatggatggataaaagtacctgttactcatgaaacacaggaagaatgtcttggg
atggcggtgttagatatgatgagaatagccaaagaaaaggatcagacccccctggacatc
tatagctctgtcagctacaagacatttttaccaaaatgtgttcgagcaaagatccaagac
tatcatattttgacaaggaagcgaataaggtacagatttcgcagatttattgagcaattc
agccattgcaaagctactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgatttt
cctgatattattgatgtcagtattaaacaagcaaaccaagaaggctcaaatgaaagcaga
attataactattcataagcaagatggtaaaagtctagaaattgaacttaggtcattaaga
gaagctttgtcttttgtgtcattaattgatggatattataggttaactgcagatgcacat
cattatctttgtaaagaagtagcacctccaatggtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggattttgccatcagtaaactgaagaaagccggtaatcagact
ggactctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gttgagagagaaaacgtcattgaatataagcactgtttgattacaaaaaatgaaaatgga
gaatacaacctcagtggtactaagaagaacttcagtaatcttaaagatcttttgaattgc
tatcagatggaaactgttcgctcagacagtataattttccagtttactaaatgctgtccc
ccaaagccaaaagataaatcaaaccttctagtcttcagaaccaatggtatttctgatgta
ccaacctcaccaacattacagaggcataataatgtgaaccaaatggtgttccacaaaatc
agaaatgaagatttgatatttcatgaaagccttggccaaggaacttttaccaaaattttt
aaaggtgtaagaagagaagtaggagactatggtcaactgcatgaaacagaagttctctta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaaacatctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtaaaatttggatcactagatatatatctgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacagctggcatgggcc
atgcattttctagaagaaaaaacccttattcatgggaatgtgtgcaccaaaaatattctt
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattctgcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaatctggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataagcccctgagtgctttggattctcaa
agaaaactacagttttatgaaaataggcaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattacgaaccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattacgaactattaacagaaaatgac
atgttacctaatatgagaataggtgccctagggttttctggtgcttttgaagaccgagac
cctacgcaatttgaagagagacacttgaaatttctacagcaacttggcaagggtaatttt
gggagtgtggagatgtgccggtatgaccctctacaagacaacactggagaggtggtggct
gtgaagaagctccagcacagtactgaagagcacctcagagactttgaaagggaaattgaa
atccttaaatcattgcaacatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactat
ctccaaaaacataaagaacggatagatcataaaaaacttcttcagtacacatctcaaata
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaagg
aatatattggtggagaatgaaaacagagttaaaataggagattttggcttaactaaagtg
ttgccacaaggcaaagaatactacaaagtgaaagaacctggtgaaagtccaatattctgg
tatgcgccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagcttt
ggagtggttctgtatgaacttttcacatatattgagaagagtaaaagcccaccagcggaa
tttatgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaa
ctcctgaagaataatggaagattaccaagaccagatggatgcccagatgagatgtatgta
atcatgacagaatgctggaacaataatgtaaaccaacgcccctctttcagagacctagct
cttcgagttgatcaaataagagacagcatggctggatga
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