KEGG   Physeter macrocephalus (sperm whale): 102979718
Entry
102979718         CDS       T06011                                 
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
  KO
K18437  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad00230  Purine metabolism
pcad01100  Metabolic pathways
pcad04927  Cortisol synthesis and secretion
pcad04934  Cushing syndrome
pcad05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102979718 (PDE8B)
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    102979718 (PDE8B)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    102979718 (PDE8B)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102979718 (PDE8B)
Enzymes [BR:pcad01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     102979718 (PDE8B)
SSDB
Motif
Pfam: PDEase_I PDE8A_N PDE8 PAS_9 PAS PAS_3 PAS_4 PAS_8
Other DBs
NCBI-GeneID: 102979718
NCBI-ProteinID: XP_023977308
Ensembl: ENSPCTG00005002983
UniProt: A0A2Y9SFX7
LinkDB
Position
8:78190000..78471363
AA seq 885 aa
MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPAAPLHGLFVQTDAADAIPPSRASW
PPGAARGRRARGELGSGSSAGSTGPAATTCRGRSRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYKCNIARTPESALECFLDKHHEII
VIDHRQTRNFDAEEVCRSIRATNPSEHTVILAVVSQASGNYEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELDELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDKNKQIHKVHRDSGDNSQTESHSFRYKNRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVPQSHSHLGMPVTI
NDVPPSIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCSETTLRAW
LQVIESNYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPIGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPTLMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq 2658 nt   +upstreamnt  +downstreamnt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccaactcgccccgccagaccaccagcgtgtcgcagggccccgcggcccccctg
cacggcctcttcgtccagaccgacgccgccgacgccatccccccgagccgcgcgtcctgg
ccccccggtgccgcccgcggccgcagggcccgcggtgagctgggcagcggcagcagcgcg
ggctccacgggccccgcggcgaccacctgcaggggccggagtcgccactgctgcagcagc
gcggaggccgagacccagaccagctacaccagcgtcaagcaggtctcttctgcagaggta
cgcatcgggcccatgagactgacgcaggatcctatccaggttttgctgatctttgcaaag
gaagacagtcagagtgatggattctggtgggcctgtgacagagccggttacaaatgtaat
attgctcggactccggagtcagccctggaatgctttctagataaacatcatgagattatt
gtgatcgaccacagacaaactcgaaactttgatgcagaagaagtgtgcaggtcgatccgg
gccacaaatccctcggagcacacggtgattcttgcggtggtttcacaagcatctggcaac
tatgaagaggcctcggtgctccctcttctgcacgcaggcttcaaccggagatttatggag
aatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcgc
tcacagttcaagttaagggcctgtaattcagtgtttacagcattagaccactgtcatgaa
gccatagaaatcacaagcgatgaccacgtgattcagtatgtcaacccagcctttgaaagg
atgatgggctaccacaaaggtgagctcctggggaaagaactcgacgagctgcccaaaagt
gacaagaaccgggcggaccttcttgacaccatcaacacctgcatcaagaagggcaaggag
tggcagggggtttactatgccagacggaaatccggcgacagcatccaacagcatgtgaag
atcactccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactg
tgttgtaccactgacaaaaataagcagattcacaaggttcatcgtgactcaggagataat
tctcaaacagagtctcattcattcagatacaagaacaggaggaaagagtccattgatgtg
aaatcaatatcatctcgaggcagtgatgcaccaagcctacagaatcgtcgctatccatcc
atggcaaggatccattccatgaccatcgaggctcccatcacaaaggttataaatataatt
aatgcagcccaagaaaacagtcctgtcacagtagcagaagccttggacagagttttagaa
attttacggaccacagaactgtactcccctcagctgggtaccaaagatgaagatccccac
accagtgatctcgtgggaggcctgatgactgatggcttgagaaggttgtcaggaaacgag
tatgtgttcactaagaatgtgccccagagtcacagtcaccttgggatgccagtaaccatc
aatgatgttcccccttctatcgctcaattacttgataatgaggaaagctgggagttcaac
atctttgaattggaagctgtgacgcacaaaaggccattggtttacctgggcttaaaagtc
ttttcccggtttggagtatgtgaatttttacactgttctgaaactacccttcgggcctgg
ctccaagtgattgaatccaactaccactcctccaatgcttaccacaactccactcatgcc
gctgatgtcctgcacgccactgccttcttcctcggaaaagaaagagtgaagggaagcctc
gatcagctagatgaggtggctgccctgattgctgccacagtccatgacgtggatcaccca
ggaaggaccaactctttcctgtgcaacgcaggcagtgaactcgccgtgctctataatgac
actgctgtcttggagagtcaccacacagccctggccttccagctcacagtcaaggacagc
aaatgcaacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctatt
attgatatggttttagcaacagagatgacaaaacactttgaacacgtgaacaaatttgtg
aacagcatcaacaagccaatggcagctgagattgaaggcagtgactgtgaatgcaaccct
attgggaagaactttcctgaaaatcaaatcctgattaagcgcatgatgattaagtgtgct
gacgtggccaatccatgccgccccctggacctatgtatcgaatgggccggaaggatctcc
gaggagtactttgcacagactgatgaagagaagagacaggggctacctgtagtgatgcca
gtgtttgaccggaatacctgtagcatccccaagtctcagatttcctttattgactacttc
ataacagacatgtttgatgcttgggatgcctttgcacacctgccaaccctgatgcaacat
ttggccgataactacaaacactggaagacattagatgacctaaagtgcaaaagtctgagg
cttccatctgacagctaa

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