Physeter macrocephalus (sperm whale): 102980935 Help Entry 102980935         CDS       T06011                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism pcad  Physeter macrocephalus (sperm whale) Pathway pcad01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:pcad00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102980935 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:pcad03032]     102980935 (TOP2A)    03036 Chromosome and associated proteins [BR:pcad03036]     102980935 (TOP2A) Enzymes [BR:pcad01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      102980935 (TOP2A) DNA replication proteins [BR:pcad03032]  Eukaryotic type   DNA Topoisomerases    102980935 (TOP2A) Chromosome and associated proteins [BR:pcad03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     102980935 (TOP2A)   Centrosome formation proteins    Centriole proteins     102980935 (TOP2A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  102980935 NCBI-ProteinID:  XP_007112560 Ensembl:  ENSPCTG00005010563 UniProt:  A0A2Y9F0L8 LinkDB All DBs Position 14:115912609..115939117 Genome browser AA seq 1533 aa AA seqDB search MEVSPLQPVNDNMQVNKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVESVTQQ MWVYDEDIGINCREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVE TASREYKKMFKQTWMDNMGRAGEMELRPFSGEDYTCITFHPDLSKFKMQSLDKDIVALMV RRAYDIAGSTKDVKVFLNGNKLPIKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVC LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQ VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK YGVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEVAFYSLPEFEEWKS STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW YIPIIPMVLVNGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY HTDTTVKFVVKMTEEKLAEAERVGLHRVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKRDSVTDSGPTFNYLLDMPLWYLTKEK KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQIGLPGKGGKA KGKKTQRAEVLPSPCGKRVIPQVTIEMKAEAEKKIKKKIKNENTEGSPQEDGMEIEGLKQ RLEKKQKREPGTKTKRQTTLPFKPVKKAKKRNPWSDSESDMSSNESNFDVPPREKEPRRA ATKTKFTMDLDSDENFSDFDENSQDEDFVPSDASPPRTKTSPKHTNKELKPQKSATSETD LNDDDAKDNVPLPPSSPAADFPALTKTINPVPKKNVTVKKTAAKSQSSTSTTGAKKGAAP KRTKKDPDLDSDVSKKPNPPKTKSRRKRKLSTSDDSDSNFEKMISKTVTSKKPKEDSDDF HLDLDSAVASRAKSGRTKKPIKYLEESDEDDLF NT seq 4602 nt NT seq  +upstreamnt  +downstreamnt atggaggtgtcgccactgcagcctgtaaatgacaatatgcaagtcaacaaaacaaagaaa aatgaagatgctaagaaaagactgtctattgaaagaatctatcaaaagaagacacaactg gaacatattctgctccgcccagacacctacattggctctgtggaatcagtgacccagcaa atgtgggtttacgatgaagatattggcattaactgtagggaagtcacttttgttcctggt ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagagaccca aaaatgtcttgtattagagtcacaattgacccggagaataatttaattagtatatggaat aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc atctttggacagctcctaacttctagtaactatgatgatgaagaaaagaaagtaacaggt ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaa acagccagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggaga gctggtgagatggaactcaggccctttagtggagaagattatacatgtattaccttccac cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggtt agaagagcgtatgatattgctggatccactaaagatgtcaaggtctttctcaatggaaat aagcttccaataaaaggattccgtagctatgtagatatgtatctgaaggataaggtagat gaaactggcaatccactgaaaattatccatgaacaagtaaaccccaggtgggaagtgtgt ttaacaatgagtgaaaaaggctttcaacaaatcagctttgtcaacagcattgctacttcc aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt gtgaagaaaaagaacaagggtggtgttgcagtaaaagcacatcaggtaaaaaatcacatg tggatttttgtgaatgccttaattgaaaacccaaccttcgactcccagacaaaagagaac atgactttacaagtcaagagctttggatcaacatgccaactgagtgaaaaattcatcaaa gctgcaactggctgtggtattgtagaaagcatactaaattgggtgaaatttaaggcccaa gtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaaaggaattcccaaa cttgatgatgccaatgatgcaggaggccgaaactccactgagtgtacacttatcctgaca gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaag tacggggttttccccctaagaggaaaaatgcttaatgttcgagaagcttctcataagcag ataatggaaaatgctgaaattaacaatataatcaagattgtgggtcttcagtacaagaaa aactatgaagatgaagattcattgaagactctgcgttacgggaagataatgattatgaca gatcaggaccaagacggttcccatatcaaaggcttgctgattaattttatccatcataac tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg tctaaaaacaagcaagaagtggcattctatagccttcctgagtttgaagaatggaagagt tctacgccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca tcaaaagaagctaaagagtactttgcagatatgaaaagacatcgtatccaattcaaatat tcaggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat cgaaaggaatggttaactcatttcatggaagatagaaggcaacgaaagttacttggcctt cctgaggattacttatatgggcaaactaccacgtatctgacatacaatgacttcataaac aaggaacttatcctgttctcaaattctgataatgagaggtctatcccatctatggtggat ggtttgaaaccaggtcagagaaaggttttgtttacatgtttcaaacggaatgacaagcga gaggtgaaggttgcccagttagctgggtcagtagctgagatgtcctcttatcatcatggt gagatgtcactaatgatgaccattatcaatttggctcagaactttgtgggtagcaataat ctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca aaagatgatcacacgttaaagtttttatatgatgacaaccaacgtgttgagcctgaatgg tacattcctattatacccatggtgctggtaaatggcgctgaaggaattggtactggctgg tcctgcaaaatccccaactttgatgttcgtgaagttgtgaataatatcagacgtttgatg gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactattgaa gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattctacaacc attgaaatctcagagcttcccatcagaacatggacccagacatataaagaacaggttcta gaacccatgttgaatggcactgagaagacaccccctctgataacagattatagggaatac cacacagacaccactgtgaagtttgttgtgaagatgactgaagaaaaactggcagaggca gagagagttggactacacagagtcttcaaactccaaactagtctcacatgcaactctatg gtgctttttgaccacgtaggctgtttaaagaaatacgacacagtgttggatattctaaga gacttctttgaactcaggcttaaatattatggattaagaaaagagtggcttctaggaatg cttggtgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatagat ggcaaaataatcatcgaaaacaagcctaagaaagaattaattaaagttctgattcaaaga ggctatgattcggatcctgtgaaggcttggaaagaagcccagcaaaaggttccagatgaa gaagaaaatgaagagagtgacaatgaaaaggaaactgaaaagagagactctgtaacagat tctggaccaaccttcaactaccttcttgatatgcctctttggtatctaaccaaggaaaag aaagatgaactgtgcaaactaagaaatgaaaaagagcaagagctagaaacattaaagaga aagagtccatcagatttgtggaaagaagatttggctgcttttattgaagagctggaggct gttgaagcaaaggagaaacaagatgaacaaataggacttcctgggaaaggtgggaaagca aaggggaaaaaaacacaaagggcagaagttttgccttctccatgtggaaaaagagtcatc ccccaagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaaaaaaattaag aatgaaaatactgaaggaagccctcaagaggatgggatggaaatagaaggcttaaaacag agattagaaaagaaacagaaaagagaaccaggtaccaagacaaagagacaaactacattg ccatttaaaccagtcaagaaagccaaaaaaagaaacccctggtctgattcagaatcagat atgagcagtaacgaaagtaattttgatgtccctccccgagaaaaagagccacggagagca gcaacaaaaaccaaattcacaatggatttggattcagatgaaaatttctcagattttgat gaaaacagtcaagatgaagattttgtcccatcagatgctagtccacctaggaccaaaact tccccaaaacatactaacaaagaactgaagccacagaaaagtgccacatcagaaacggac cttaatgatgatgatgccaaggataatgtaccacttcctccaagctctcctgctgctgat ttcccagctttaactaaaaccataaaccctgttcctaaaaagaatgtgacagtgaagaag acagcagcaaaaagtcagtcttccacctctactacaggggccaaaaaaggggctgcacca aaaagaaccaaaaaggatccagacttggattctgatgtctctaaaaagcctaatcccccc aaaaccaagagtcgccgcaaaaggaagctgtccacttctgatgattctgactctaatttt gagaaaatgatttctaaaacagtcacaagcaagaaacccaaggaggacagcgatgacttc catctggacttagactcagctgtggcttctcgggcaaaatctggacggacaaagaaacct ataaagtacctcgaagaatcagatgaagatgatctgttttaa

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