Physeter macrocephalus (sperm whale): 102981101
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Entry
102981101 CDS
T06011
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 isoform X1
KO
K12385
Niemann-Pick C1 protein
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
pcad04142
Lysosome
pcad04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
102981101 (NPC1)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
102981101 (NPC1)
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
102981101 (NPC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
pcad02000
]
102981101 (NPC1)
Transporters [BR:
pcad02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
102981101 (NPC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
ACR_tran
Motif
Other DBs
NCBI-GeneID:
102981101
NCBI-ProteinID:
XP_007127269
Ensembl:
ENSPCTG00005022232
UniProt:
A0A2Y9FQP0
LinkDB
All DBs
Position
19:complement(37548467..37595908)
Genome browser
AA seq
1277 aa
AA seq
DB search
MNACGPALGLLLLLLCPTQVFSQSCVWYGECGIASGDKRYNCRYSGLPKPLPEDGYDLVQ
ELCPGFFFGNVSLCCDVQQLRTLKDKLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQF
LNVTATEDYVDPVTNQTKTNVKELQCYVGESFANAMYNACRDVEAPSSNEKALGLLCGKE
AEACNATNWIEYMFNKNNGQAPFTITPIFSDLPAHGMEPMNNATKGCDESVDEVTGPCSC
QDCSIVCGPKPQPPAPPVPWRILGLDAMYVIMWSTYMGFLLVFFGAFFAVWCYRKRYFVS
EYTPIDGNIAFSVNASDKGGPSCCDSLGAAFEARLQRLFTQWGSFCVRHPGCIVFFSVAF
IATCSSGLVFVQVTTDPVDLWSAPGSQARREKEYFDTHFGPFFRTEQLIIQAPLTQPHMY
QPYPSGADIPFGPPLAIDILHQVLDLQTAIENITASYNNKTVTLQDICLAPLSPYNKHCT
IMSVLNYFQNSHSVLDHEVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGP
VFPWLVLGGYDDQNYNNATALVITFPVNNYCNDTEKLQRAQAWEREFINFVKNYKNPNLT
ISFKAERSIEDELNRESNSDIFTVLISYGIMFLYISIALGHIKSCSTFLVDSKISLGVAG
ILIVLSSVACSLGIFSYVGIPFTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQGETL
DQQVGRVLGEVAPSIFLSSFSETVAFFLGGLSAMPAVHTFSLFAGMAVLIDFLLQITCFV
SVLGLDIKRQEKNRLDVLCCVGGTADRAGIQASESCLFHFFRNAYAPLLLKDWMRPIVVA
VFVGVLSFSIAVLNKVEIGLDQSLSMPDDSYVTDYFQSLNRYLHAGPPVYFVVEGGHDYA
SLKGQNMVCGGLGCNNDSLVQQIFTAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVY
NSTDRFCNASVVDPACVHCRPLTPEGKQRPRGADFMRFLPMFLSDNPNTKCGKGGHAAYS
AAVNILGNGTGVGATYFMTYHTVLKTSADFIDAMEKARLIASSITRTMGLEGSDHRVFPY
SVFYVFYEQYLTMIDDTIFNLGVSLGAIFLVTVVLLGCELWSAAIMCITIAMILVNMFGV
MWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSTKGSRVERAEEALSHMGSSVFSG
ITLTKFGGIMVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYVGPSINKAKSL
AAQERYRGTEREQLLNF
NT seq
3834 nt
NT seq
+upstream
nt +downstream
nt
atgaatgcgtgcggcccggccctcggcctcctcctgctgctgctctgcccgacgcaggta
ttttcacagtcctgtgtttggtatggagagtgtggaattgcatctggagataagaggtac
aattgcagatattctgggctgccaaagccattgccagaggatggctatgacctggtgcag
gaactctgtccagggttcttcttcggcaacgtcagtctttgctgtgatgttcagcagctt
cggacactgaaagacaagctgcagctgcctctgcagtttctgtccagatgtccatcctgt
ttttataacctaatgaacctgttttgtgagctgacatgtagccctcgacaaagtcagttt
ctgaatgttacagcaacggaagattatgttgatcctgttacaaaccagacaaaaacaaat
gtaaaagaattacaatgctatgttggagagagttttgccaatgccatgtacaatgcctgc
agggacgtggaggccccctcgagcaacgagaaagccctgggactgctgtgcggcaaggag
gccgaagcctgcaacgccaccaactggattgagtacatgttcaacaagaacaacggccag
gcgcctttcaccatcacacccatcttttcagatcttccagcccatgggatggagcccatg
aacaatgccaccaagggctgtgacgagtccgtggatgaggtcacggggccctgcagctgc
caggactgctcgatcgtctgtggtcccaagccccagcccccagcccctcctgttccctgg
agaatcctgggtctggacgccatgtacgtcatcatgtggagcacctacatgggattcctg
ctcgtgttttttggtgcattcttcgccgtgtggtgctacagaaaacggtattttgtctcc
gagtacacccccattgatggcaatattgctttctctgtaaatgccagtgacaaagggggg
ccgtcctgctgtgactctctgggtgccgccttcgaagcccgtctacagcggctcttcaca
cagtggggctcgttctgcgtccgacaccccggctgcatcgtgttcttctccgtggccttc
atcgccacctgttcttcgggcctggtgtttgtgcaggtcacgacagacccggtggacctc
tggtctgcgcccggcagccaggcacgccgggagaaggagtacttcgacacgcacttcgga
cctttcttccgcaccgagcagctcatcatccaagcccccctcacccagccgcacatgtac
cagccctacccctctggagccgacattccctttgggcctccacttgccatagacatcttg
caccaggttcttgacttacaaacagccatcgagaacattactgcatcttacaacaacaag
actgtgacacttcaggacatctgcttggcccccctctcaccatataacaagcactgcacc
atcatgagcgtgttaaattacttccagaacagccattccgtgctggaccacgaagtagga
gacgacttctttgtgtacgcagattaccacacacacttcctgtactgcgttcgggctccc
gcctccctgaatgacaccagtttgctccacgatccttgcctggggacctttggtggacca
gtgttcccgtggcttgtcttaggaggctatgatgatcaaaactacaataatgccacagcc
cttgtgattacctttcctgtcaataattactgtaatgatacagagaagctccagagggcc
caggcctgggaaagagagtttattaattttgtgaaaaactacaagaatccaaatctgacc
atttcttttaaggctgaacgaagtattgaagatgaactaaatcgtgaaagtaacagtgat
atcttcactgttctaatcagctatggcatcatgtttttatatatttccatagccttgggg
catatcaaaagctgtagcacgtttctggtggattcgaaaatctcgctgggcgtcgcgggc
atcctgatcgtgctgagctcagtggcgtgctccctgggcatcttcagctacgttgggatc
cccttcaccctcattgtgatagaagtcatcccgttcctggtgctggctgtgggagtggac
aacatcttcattctggtccagacctaccagagagatgaacgtctccaaggggagacgctg
gaccagcaggtgggccgggtcctgggagaagtggctccaagtattttcctgtcatccttt
tcagagacggtagcatttttcttaggaggcctctccgcgatgccagctgtgcacaccttc
tctctcttcgcggggatggcggtcctcattgacttcctccttcagattacctgttttgtg
agtgtcttggggttagacattaagcggcaagagaagaaccggctggacgtcctctgctgt
gtcgggggcacggcagacagagcaggcatccaggcctcggagagctgcttatttcacttc
ttcagaaacgcctatgctccacttctgcttaaggactggatgcggcccattgtggtagcg
gtatttgtgggtgttctgtcattcagtatcgcagtcctgaacaaagtagaaatcggcttg
gatcagtctctgtcaatgccagatgactcctatgtgacggattatttccagtccctcaat
cgctacctgcacgcgggcccgcctgtgtactttgtcgtggagggagggcacgactacgct
tctctgaaagggcagaacatggtgtgcgggggcctgggctgcaacaatgactcgctggtg
cagcagatcttcaccgccgcccagctggacaactatacccggataggctttgctccctcg
tcctggattgacgattattttgactgggtcaagccacagtcgtcttgctgtagagtctac
aacagcacggatcggttctgcaatgcgtcggtggttgaccctgcctgcgtccactgccgg
cctctgactccagagggcaagcagaggcctcggggcgcagacttcatgaggttcctgccc
atgttcctctccgataacccgaacaccaagtgtggcaaagggggacacgccgcttacagc
gcggcagttaacatcctcggcaacggcacgggcgtcggagccacgtacttcatgacctac
cacacggtgctcaagacctccgctgacttcatcgacgccatggaaaaggcccgcctcatc
gccagcagcatcaccagaaccatgggcctggaaggaagtgatcaccgtgtgttcccatac
agtgtgttctacgtcttctacgaacagtacctgaccatgattgacgacactatctttaac
ctcggcgtgtccctgggcgccatctttctggtgaccgtggttctcctgggctgtgagctg
tggtcggcggccatcatgtgcatcaccatcgctatgatcttggtcaacatgttcggtgtc
atgtggctctggggcatcagtctgaatgcggtttccttggtcaacttggtcatgagctgt
ggcatctccgtggagttctgcagccatatcacgagagcgttcacggtgagcacgaaggga
agccgcgtggaacgggcagaagaggcgctctcccacatgggcagctctgtattcagtgga
atcacactaacaaaatttggaggcattatggttttggcctttgccaaatctcaaattttc
cagatattttacttcaggatgtatttagctatggtcttactgggagccacgcatggatta
atattcctccctgtcttgctcagttacgtaggaccatcgataaataaagccaaaagtttg
gccgctcaagagcgatacagaggtacagagcgagagcaactcctcaatttctag
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