Physeter macrocephalus (sperm whale): 102981674
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Entry
102981674 CDS
T06011
Symbol
PDE11A
Name
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
KO
K13298
dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:
3.1.4.17
3.1.4.35
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00230
Purine metabolism
pcad01100
Metabolic pathways
pcad04934
Cushing syndrome
pcad05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102981674 (PDE11A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
102981674 (PDE11A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102981674 (PDE11A)
Enzymes [BR:
pcad01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
102981674 (PDE11A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
102981674 (PDE11A)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD-CE
HD
Motif
Other DBs
NCBI-GeneID:
102981674
NCBI-ProteinID:
XP_023977929
Ensembl:
ENSPCTG00005003616
UniProt:
A0A2Y9SQB2
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All DBs
Position
2:complement(82733851..83161020)
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AA seq
927 aa
AA seq
DB search
MTASRLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQSQGALGPRPTLTGTSS
VAHGGGSSSSTVGDGTGPNGSASSQHTLGGGDSGGVPLSPSWASGSCSDGSLQQRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NVPQYPPTAMDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKSLVSKFFDVHAGTPLLPCSCTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIQSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIEAPVVKFTKSFELLSPKCSADAENSFKESMEKSSYSDWLINNSVAELVA
STGLPVNISDAYQDPRFDAEAEQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAINDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSG
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERAELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVAA
NRSKWEELHQKRLLVSSAASAPLSISW
NT seq
2784 nt
NT seq
+upstream
nt +downstream
nt
atgacagcctcccgcctggactttggggaggtggaaactttcctggacaggcacccagaa
ttgtttgaagattacttgatgcggaaggggaagcaggagatggtggagaagtggctgcag
agacacagtcagagtcagggggctttaggcccaaggcccacactgactggcacaagcagc
gtggctcatggaggtggcagcagtagcagcaccgttggtgatggcacaggaccaaatggc
tctgctagcagccagcacactctgggtggtggggactcaggtggggttcccctgagtccc
agctgggccagtggcagctgcagcgatgggagcctgcagcagagagcttctcagaaagag
ctaaggaagagttttgcccgctccaaggccatccacgtgaacaggacctacgatgaacaa
gtgacctcccgggcccaggagcccctgagcagtgtgcggcggagggcacttctccggaag
gccagctccctgccccccaccactgcccacattctcagtgccctgctggaatcgcgggtg
aatgtgcctcagtacccccctaccgccatggactacaagtgccacctcaaaaagcataat
gagcgtcagttcttcctggaactggtcaaggatatctccaatgaccttgaccttaccagt
ctgagctacaagatcctcatctttgtctgcctcatggtggacgctgaccgctgctctctc
ttcctggtggaaggggcagctgctggcaagaagagcttggtctccaaattctttgacgtg
catgcaggaaccccactgctgccctgcagctgcacagaaaactcaaatgaggtgcaggtc
ccctggggcaaaggcatcattggctatgtcggggagcatggagagacggtcaacattcct
gatgcctaccaggatcgaagattcaatgatgaaattgacaagctaactggatacaagaca
aaatcattactgtgcatgcctatccaaagcagtgatggtgagattatcggtgtggcccaa
gcgataaataagattcctgaaggtgctccatttactgaagatgatgaaaaagttatgcag
atgtatcttccattttgcggaattgccatatctaatgctcagctatttgctgcctcaagg
aaagaatatgaaagaagcagggctttgctagaggtggttaatgacctctttgaagaacag
actgacctggagaaaattgtcaagaaaataatgcatcgggcccaaacactgttgaaatgt
gaacgctgttctgttttactcctagaggacatcgaagcaccagtggtgaagtttaccaaa
tcctttgaattgctgtccccaaagtgcagtgccgatgctgagaacagtttcaaagaaagc
atggagaaatcatcatactccgactggctaataaataacagcgttgctgagctggtggct
tctacaggccttccagtaaacatcagtgacgcctaccaggatccccgctttgacgccgag
gctgagcagatatctggttttcacataagatcggttctctgcgtacctatttggaatagc
aaccaccaaataattggagtggctcaagtgttaaatagacttgatgggaaacctttcgat
gacgcagatcaacgactttttgaggcttttgtcatcttttgtggccttggcatcaacaat
acaattatgtatgatcaagtgaagaagtcgtgggccaagcaatctgtggctcttgatgtg
ctatcttatcatgcaacatgttcaaaagctgaagttgacaagtttaaggcagccaacatc
cctttggtgtcagaacttgccatcaacgacatacattttgatgacttttctctcgacgtt
gacgccatgatcacggctgctcttcggatgttcatggagctggggatggtacagaaattt
aaaatcgactatgagacactgtgtaggtggcttctgactgtaaggaaaaattatcggatg
gttctataccacaactggagacatgccttcaacgtgtgccagctgatgtttgcaatgtta
actactgccgggtttcaagagattctgacggaggtggaaattttagcggtgattgtggga
tgcctgtgtcatgacctcgaccacaggggaaccaacaatgccttccaagctaagagcggc
tctgccctggcccaactctatggaacttctgctaccttagagcatcaccatttcaaccac
gcagtgatgatccttcaaagcgagggtcacaacatctttgctaatttgtcctccaaggaa
tacagtgaccttatgcagcttttgaagcagtcaatactggcaacagacctcacgctgtac
tttgagaggcgaactgaattcttcgaacttgtcagtaaaggagaatatgattggaacatc
aaaaaccatcgtgatatatttcgatcaatgttaatgacagcctgtgaccttggagccgtg
accaaaccgtgggagatctccagacaggtggctgaacttgtaaccagcgagttctttgaa
caaggagatcgggagagggcagaactcaaactcactccttcagctatttttgatcggaac
cggaaggatgagctgcctcggttgcaattggagtggatcgacagcatctgtatgcctttg
tatcaggcattggtgaaggtcaatgtgaaactgaagccgatgctggattcggtggctgcc
aacagaagtaagtgggaagagttgcaccagaaaaggctgctcgtctcttcggctgcctct
gcccctctgtcaatctcatggtga
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