KEGG   Physeter macrocephalus (sperm whale): 102982175
Entry
102982175         CDS       T06011                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X2
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad04010  MAPK signaling pathway
pcad04015  Rap1 signaling pathway
pcad04218  Cellular senescence
pcad04380  Osteoclast differentiation
pcad04620  Toll-like receptor signaling pathway
pcad04664  Fc epsilon RI signaling pathway
pcad04668  TNF signaling pathway
pcad04750  Inflammatory mediator regulation of TRP channels
pcad04912  GnRH signaling pathway
pcad04935  Growth hormone synthesis, secretion and action
pcad04936  Alcoholic liver disease
pcad05014  Amyotrophic lateral sclerosis
pcad05022  Pathways of neurodegeneration - multiple diseases
pcad05132  Salmonella infection
pcad05135  Yersinia infection
pcad05145  Toxoplasmosis
pcad05161  Hepatitis B
pcad05163  Human cytomegalovirus infection
pcad05167  Kaposi sarcoma-associated herpesvirus infection
pcad05169  Epstein-Barr virus infection
pcad05170  Human immunodeficiency virus 1 infection
pcad05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pcad05417  Lipid and atherosclerosis
pcad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102982175 (MAP2K6)
   04015 Rap1 signaling pathway
    102982175 (MAP2K6)
   04668 TNF signaling pathway
    102982175 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    102982175 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102982175 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    102982175 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102982175 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    102982175 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102982175 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102982175 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102982175 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102982175 (MAP2K6)
   05161 Hepatitis B
    102982175 (MAP2K6)
   05163 Human cytomegalovirus infection
    102982175 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102982175 (MAP2K6)
   05169 Epstein-Barr virus infection
    102982175 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102982175 (MAP2K6)
   05135 Yersinia infection
    102982175 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102982175 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102982175 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    102982175 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102982175 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    102982175 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102982175 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcad01001]
    102982175 (MAP2K6)
Enzymes [BR:pcad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     102982175 (MAP2K6)
Protein kinases [BR:pcad01001]
 Serine/threonine kinases: STE group
  STE7 family
   102982175 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 102982175
NCBI-ProteinID: XP_028355424
Ensembl: ENSPCTG00005008065
UniProt: A0A455C6B6
LinkDB
Position
14:complement(130697355..130826912)
AA seq 358 aa
MPCLFLSPVPSLDLRPHFCRSQPETHPRSGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSK
ACISIGNQNFEVKADDLEPIVELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRL
LMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILG
KIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGC
KPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSP
QLPADKFSEEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKATDVASFVKSILGD
NT seq 1077 nt   +upstreamnt  +downstreamnt
atgccttgcctcttcctctcccccgtcccctccctcgacctccgaccacacttctgcagg
agccagcctgagacacaccctcgctcaggcaagaagcgaaaccctggccttaaaatcccc
aaagaagcatttgaacaacctcagaccagttccacgccacctcgagatttagactccaaa
gcttgcatttctattggaaatcagaactttgaggtgaaggcggatgacctggagcctata
gtggagctgggccggggggcgtacggggtggtggagaagatgcggcatgtgcccagcggg
cagatcatggcggtgaagcggatccgggccacagtaaatagccaggagcagaaaaggtta
ctgatggatttggatatttccatgaggaccgtggactgtccttttacggtcaccttttat
ggcgcactcttccgtgagggggatgtctggatctgcatggagctcatggacacgtcccta
gataaattctacaaacaagtgattgataaaggccaaacaattccagaggacatcttaggg
aaaatagcagtttctattgtaaaagcattagaacatttacacagtaagctctctgtcatt
catcgagatgtcaagccttccaatgtgctcatcaacaccctgggccaggtgaagatgtgc
gattttggaatcagcggctaccttgttgactccgtcgctaaaactattgatgcaggatgc
aaaccgtacatggccccagagagaataaacccagagctcaaccagaagggatacagcgtg
aagtccgacatttggagtctgggcatcaccatgatcgagctggccatccttcggtttccc
tatgattcgtggggaactccttttcagcagctcaaacaggtggtggaggagccgtcgcca
caactccccgcagacaagttctccgaagagtttgttgactttacctcacagtgcttgaag
aagaattccaaagaaaggccaacatatccagagcttatgcaacatccatttttcacccta
catgaatccaaagcgacagacgtggcatcttttgtaaaatcgattcttggagactaa

DBGET integrated database retrieval system