Physeter macrocephalus (sperm whale): 102982777 Help Entry 102982777         CDS       T06011                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism pcad  Physeter macrocephalus (sperm whale) Pathway pcad00010   Glycolysis / Gluconeogenesis pcad00620   Pyruvate metabolism pcad01100   Metabolic pathways pcad01200   Carbon metabolism pcad01230   Biosynthesis of amino acids pcad04910   Insulin signaling pathway pcad04930   Type II diabetes mellitus pcad04932   Non-alcoholic fatty liver disease pcad04950   Maturity onset diabetes of the young Module pcad_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate pcad_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:pcad00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     102982777 (PKLR)    00620 Pyruvate metabolism     102982777 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102982777 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102982777 (PKLR)    04950 Maturity onset diabetes of the young     102982777 (PKLR)    04932 Non-alcoholic fatty liver disease     102982777 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pcad04147]     102982777 (PKLR) Enzymes [BR:pcad01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      102982777 (PKLR) Exosome [BR:pcad04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    102982777 (PKLR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Motif Other DBs NCBI-GeneID:  102982777 NCBI-ProteinID:  XP_007108925 Ensembl:  ENSPCTG00005019603 UniProt:  A0A2Y9ETZ0 LinkDB All DBs Position Unknown AA seq 573 aa AA seqDB search MSVQDNMRPMWLWSWISKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQELGTSFFQQQL PAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIRAGMNIARLNFSH GSHEYHAESIANVREAVESFATSPLSYRPVAIALDTKGPEIRTGILQGGPASEVELVKGS QVLVTVDPAFRTRGDANTVWVDYPNIVQVVPVGGRIYIDDGLISLEVTKIGPEGLETQVE NGGVLGSRKGVNLPGAQVDLPGLSEQDVQDLRFGVEHGVDIIFASFVRRASDVAAVRAAL GPEGQGIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCN LAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQ HAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSA QLLSQYRPRAAVIAVTRSAQAARQAHLCRGVFPVLYREPPEAIWADDVDRRVQFGIESGK LRGFLRFGDLVIVVTGWRPGSGYTNIMRVLSIT NT seq 1722 nt NT seq  +upstreamnt  +downstreamnt atgtcagtgcaggacaacatgcgacccatgtggctttggtcatggatctctaagtcccaa agggatttagcaaagtccatcctgattggggctccaggaggaccagcggggtacctgcgg cgggctagtgtggcccagctgacccaggagctgggcacttccttcttccagcagcagctg ccagctgctatggcagacaccttcctggaacacctctgcttgctggacatcgactccgag cctgtggccgctcgcagtaccagcatcattgccaccattgggccggcatctcgctccgtg gaacgcctcaaggagatgatcagggccgggatgaacattgcgagactcaacttctcccac ggctcccatgagtaccatgctgaatccatcgccaacgtccgggaggcggtggagagcttt gcaacttccccgctcagctaccgacccgtggccatcgctctggacaccaagggaccggag atacgcactgggatcctgcaggggggccctgcgtcggaagtggagctagtgaagggctcc caggtgctggtgactgtggacccggcgttccggacgcggggggacgcgaacaccgtgtgg gtggactaccccaatattgtccaggtcgtgccggtggggggccgcatctacattgacgac gggctcatctccctagaggtcacgaaaatcggtccagaggggctggagacccaagtggag aacggcggtgtcctgggcagccggaagggcgtgaacttgccaggggcccaggtggacctg cccgggctgtccgagcaagatgtccaggacctgcgcttcggggtggagcatggcgtggac atcatctttgcctcctttgtgcggagagccagtgacgttgctgccgtccgggctgctctg gggccggaaggacagggcatcaagatcattagcaaaatcgagaaccacgaaggcgtgaag aagtttgatgaaatcctggaggtgagcgacggcattatggtggcacggggtgacctgggc attgagatcccagccgagaaggttttcctggctcagaagatgatgattggccgttgcaac ttggcgggaaagcccgttgtctgtgctacacagatgctggagagcatgatcactaagccc cggccaacccgggcagagacgagtgatgtggccaacgccgtgctcgatggggcagactgc atcatgctgtcgggggagactgccaaaggcaactttcctgtggaggctgtaaagatgcag catgcgattgcccgggaggcagaggctgccgtgtaccaccggcagctctttgaggagctg cgccgagcagcaccgctgagccgggatcccaccgaggtcaccgctattggcgctgtggag gctgccttcaagtgctgtgctgctgccatcatcgtgctgacgacaactggccgctcagcc cagcttctgtctcagtaccgacctcgggcagcagtcattgctgtcacccgctctgcccag gctgcccgccaggcccacctgtgccggggagtcttccctgtgctctaccgtgaacctcca gaggccatctgggcagacgatgtggatcgccgagtccaatttggcattgaaagtggaaag ctccgtggcttcctccgttttggggacctggtgattgtggtgacaggctggcgaccgggc tccggctataccaacattatgcgggtgctgagcataacctga

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