KEGG   Physeter macrocephalus (sperm whale): 102984157
Entry
102984157         CDS       T06011                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad04010  MAPK signaling pathway
pcad04022  cGMP-PKG signaling pathway
pcad04137  Mitophagy - animal
pcad04141  Protein processing in endoplasmic reticulum
pcad04151  PI3K-Akt signaling pathway
pcad04210  Apoptosis
pcad04211  Longevity regulating pathway
pcad04261  Adrenergic signaling in cardiomyocytes
pcad04668  TNF signaling pathway
pcad04720  Long-term potentiation
pcad04722  Neurotrophin signaling pathway
pcad04725  Cholinergic synapse
pcad04728  Dopaminergic synapse
pcad04911  Insulin secretion
pcad04912  GnRH signaling pathway
pcad04915  Estrogen signaling pathway
pcad04918  Thyroid hormone synthesis
pcad04922  Glucagon signaling pathway
pcad04925  Aldosterone synthesis and secretion
pcad04926  Relaxin signaling pathway
pcad04927  Cortisol synthesis and secretion
pcad04928  Parathyroid hormone synthesis, secretion and action
pcad04932  Non-alcoholic fatty liver disease
pcad04934  Cushing syndrome
pcad04935  Growth hormone synthesis, secretion and action
pcad05010  Alzheimer disease
pcad05012  Parkinson disease
pcad05014  Amyotrophic lateral sclerosis
pcad05020  Prion disease
pcad05022  Pathways of neurodegeneration - multiple diseases
pcad05030  Cocaine addiction
pcad05031  Amphetamine addiction
pcad05034  Alcoholism
pcad05161  Hepatitis B
pcad05163  Human cytomegalovirus infection
pcad05166  Human T-cell leukemia virus 1 infection
pcad05203  Viral carcinogenesis
pcad05207  Chemical carcinogenesis - receptor activation
pcad05215  Prostate cancer
pcad05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102984157 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102984157 (ATF4)
   04668 TNF signaling pathway
    102984157 (ATF4)
   04022 cGMP-PKG signaling pathway
    102984157 (ATF4)
   04151 PI3K-Akt signaling pathway
    102984157 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    102984157 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    102984157 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    102984157 (ATF4)
   04922 Glucagon signaling pathway
    102984157 (ATF4)
   04912 GnRH signaling pathway
    102984157 (ATF4)
   04915 Estrogen signaling pathway
    102984157 (ATF4)
   04926 Relaxin signaling pathway
    102984157 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    102984157 (ATF4)
   04918 Thyroid hormone synthesis
    102984157 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    102984157 (ATF4)
   04925 Aldosterone synthesis and secretion
    102984157 (ATF4)
   04927 Cortisol synthesis and secretion
    102984157 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102984157 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    102984157 (ATF4)
   04728 Dopaminergic synapse
    102984157 (ATF4)
   04720 Long-term potentiation
    102984157 (ATF4)
   04722 Neurotrophin signaling pathway
    102984157 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    102984157 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    102984157 (ATF4)
   05203 Viral carcinogenesis
    102984157 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    102984157 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102984157 (ATF4)
   05161 Hepatitis B
    102984157 (ATF4)
   05163 Human cytomegalovirus infection
    102984157 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102984157 (ATF4)
   05012 Parkinson disease
    102984157 (ATF4)
   05014 Amyotrophic lateral sclerosis
    102984157 (ATF4)
   05020 Prion disease
    102984157 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    102984157 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    102984157 (ATF4)
   05031 Amphetamine addiction
    102984157 (ATF4)
   05034 Alcoholism
    102984157 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102984157 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102984157 (ATF4)
   04934 Cushing syndrome
    102984157 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pcad03000]
    102984157 (ATF4)
Transcription factors [BR:pcad03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    102984157 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 AAA_13 Laminin_II KIF9 KIF21A OVT1 Asd-4 DUF3450 DUF4407 DUF724 Fez1 bZIP_Maf
Other DBs
NCBI-GeneID: 102984157
NCBI-ProteinID: XP_023983227
Ensembl: ENSPCTG00005014040
UniProt: A0A2Y9T136
LinkDB
Position
Unknown
AA seq 352 aa
MAEMSFLSSEVLVGDFVSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSGDKAKAGFSE
WLAVDGLVSASSNGKEDAFSGTDWMVEKMDLKEFDFNGLLGVDDLETMPDELLATFDDTC
DLFDPLLQEATKEPPQIVNPIGHLPESLPTTDQGAPLTFLQPLPLSPGALSSIPDHSFTL
ELCSEVVISEEDRKPDSTAYITVNPQCVKEEDAPSDNDSGICMSPDSYLGSPQHSPPTSR
GSPNRSLLSPGAPGGSARPKPYDPLGEKMIAAKVKGEKLDKKLKKMEQNKTAATRYRQKK
RAEQEALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKARGKKRIP
NT seq 1059 nt   +upstreamnt  +downstreamnt
atggccgagatgagcttcctgagcagcgaggtgttggtgggggacttcgtgtcccccttc
gaccagtcgggtttgggggctgaagagagcctgggtctcctggatgactacctggaggtg
gccaagcacttcaaacctcatgggttctctggcgacaaggctaaggcgggcttctccgaa
tggctggctgtggatgggttggtcagtgcctcaagtaacggcaaggaggatgctttctct
gggacagattggatggtggagaaaatggatctgaaggagtttgattttaatggcctgttg
ggtgtagacgatctggaaaccatgccagatgagcttttggccacgttcgatgacacgtgt
gatctctttgaccccctactccaggaggctactaaggagcccccccagatagtgaaccca
ataggccatcttccagaaagtttgccaacaactgaccagggtgcccctttaactttctta
cagcctcttcccctctccccaggggccctgtcctccattccagatcattcttttacttta
gagctatgcagtgaagtggtgatctctgaagaagataggaagccagactccactgcttac
attacggtgaaccctcagtgcgtaaaggaagaggatgccccctcagataatgatagtggc
atctgtatgagccctgactcctatctgggctctccccagcatagcccccctacctccagg
ggctctccaaatagaagcctgctatctccaggtgcccctggtggctctgcccgccccaaa
ccctatgaccctcttggagagaagatgatagcagcaaaagtaaagggtgagaaactagat
aagaaactgaagaaaatggagcagaacaagacagcagccactaggtaccgccagaagaag
agggcagagcaggaggccctcactggtgaatgtaaagagctagaaaagaagaatgaggct
ctgaaagagaaggcagattccttggccaaggagatccagtatctgaaagatttaatagaa
gaggtccgcaaggcaagggggaagaagaggatcccctag

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