Physeter macrocephalus (sperm whale): 102984239
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Entry
102984239 CDS
T06011
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon isoform X2
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00564
Glycerophospholipid metabolism
pcad00565
Ether lipid metabolism
pcad00590
Arachidonic acid metabolism
pcad00591
Linoleic acid metabolism
pcad00592
alpha-Linolenic acid metabolism
pcad01100
Metabolic pathways
pcad04010
MAPK signaling pathway
pcad04014
Ras signaling pathway
pcad04072
Phospholipase D signaling pathway
pcad04217
Necroptosis
pcad04270
Vascular smooth muscle contraction
pcad04370
VEGF signaling pathway
pcad04611
Platelet activation
pcad04664
Fc epsilon RI signaling pathway
pcad04666
Fc gamma R-mediated phagocytosis
pcad04724
Glutamatergic synapse
pcad04726
Serotonergic synapse
pcad04730
Long-term depression
pcad04750
Inflammatory mediator regulation of TRP channels
pcad04912
GnRH signaling pathway
pcad04913
Ovarian steroidogenesis
pcad04921
Oxytocin signaling pathway
pcad05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
102984239 (PLA2G4E)
00565 Ether lipid metabolism
102984239 (PLA2G4E)
00590 Arachidonic acid metabolism
102984239 (PLA2G4E)
00591 Linoleic acid metabolism
102984239 (PLA2G4E)
00592 alpha-Linolenic acid metabolism
102984239 (PLA2G4E)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
102984239 (PLA2G4E)
04072 Phospholipase D signaling pathway
102984239 (PLA2G4E)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102984239 (PLA2G4E)
04664 Fc epsilon RI signaling pathway
102984239 (PLA2G4E)
04666 Fc gamma R-mediated phagocytosis
102984239 (PLA2G4E)
09152 Endocrine system
04913 Ovarian steroidogenesis
102984239 (PLA2G4E)
04921 Oxytocin signaling pathway
102984239 (PLA2G4E)
09156 Nervous system
04724 Glutamatergic synapse
102984239 (PLA2G4E)
04726 Serotonergic synapse
102984239 (PLA2G4E)
04730 Long-term depression
102984239 (PLA2G4E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
102984239 (PLA2G4E)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
102984239 (PLA2G4E)
Enzymes [BR:
pcad01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
102984239 (PLA2G4E)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
102984239
NCBI-ProteinID:
XP_023974054
Ensembl:
ENSPCTG00005015444
UniProt:
A0A2Y9SE47
LinkDB
All DBs
Position
11:96476773..96519994
Genome browser
AA seq
830 aa
AA seq
DB search
MLQKQMLVSVSHNPSHPSQEEDGRPSATCTLEEELSPCHLLTVRVIRMKNVRQADVLSQT
DCFVSLWLPTTSKKRLRTRTISNCRNPEWNETFKFQIQTQVKNVLELSICDEDTVTPDDH
FLTVLYDLTKLCFREKTHVKFPLNTEGMEELEVEFLLEESPSPPESLITNGVLVSRQVSC
LEVHAESRRQTNRKMKDLLVTVTESFEHTQHISHCLDPCHPNSACFHYPKYFQPQVHVEL
SCCGAYKNGPVCQPLDCLRDGQAVTLPVSKNCELHMKSTPCSEALDVRLGFSLCQAELEF
LQKRRVVVAEALKQVLQLEEDLQADEVPLIAIMATGGGTRSMTAMYGHLLGLQKLNILNC
ASYITGLSGATWTMATLYRDPDWSSKNLELAILEARRHVVKDKMPALFPDQLLKFQKELQ
QRRQEGYKVTFTDFWGLLVEACLGDERNECKLSDQSAALCQGQNPLPIYLTVNVKDDISN
QDFREWFEFSPYEVGLPKYGGFIPTELFGSEFFMGRLMRRIPESRMCYMLGLWSSIFSLN
LLDAWNLSHNSEEFFHRWTRERVHDIEDEPHLPEIPKCDANILDTTVVMPGSWLSNTFRN
ILTYRAFVSEFHNFLLGLQLHTDYHQNGQFATWKDTVLDGFPNQLTGSVNHLCLLDTAFV
INSSYPPILRPERKADLIIHLNYCAGSQTKPMKQTCKYCTEQNIPFPKYEVQEEDDNLKE
CYLLENSQEPNAPIVIFFPLINDTFQKYKAPGVERSPEELEQGQVDIYGPKSPYTTKELT
YTEAAFDKLVKLSEYNILNNKDKLLQALRLAVEKKKRLKSQCPPKVPGHP
NT seq
2493 nt
NT seq
+upstream
nt +downstream
nt
atgctgcagaagcagatgcttgtctcagtctcccacaacccgtcacacccaagccaagaa
gaagatggcaggccctccgccacctgcaccttggaggaggagctgtctccatgccacctg
ctgacagtgagggtcatccggatgaaaaacgtccgacaggctgacgtgttaagccagaca
gactgctttgtgagcctctggctgcccaccacctctaaaaagaggctgaggactaggacc
atctccaactgccgaaacccagagtggaatgaaaccttcaagttccagatccagacccaa
gtgaagaacgtgctagagctgagcatctgtgatgaagacacggtgacaccagatgaccat
ttcttgacagttctctatgacctcaccaagctctgcttccgagagaaaacccatgtgaag
ttcccactcaacacagagggcatggaggagctggaggtggagttcctgctggaggagagc
ccctctccacctgagagtctcatcaccaatggcgtgctggtgtctcgacaagtgtcctgc
ctggaggttcatgcagaatccaggagacagacgaataggaaaatgaaggacctcctggtg
acagtgacggagtccttcgagcacacccagcacatctcacactgcctggatccctgccac
ccaaactctgcctgcttccactaccccaagtacttccagccccaggtccacgtggagctt
tcctgctgcggtgcgtacaagaacggtcctgtgtgccagcccctggattgcctgcgtgac
ggccaggcggtgaccctgcctgtgagcaagaattgtgaattacacatgaagtctacaccc
tgctccgaggcactggacgtgcggctgggcttcagcctgtgccaggcagagctggagttc
ctgcagaagcggagggtggtggtggctgaggcgctgaagcaggtgttgcagctggaggag
gacctgcaggcagacgaggtcccactgatagccatcatggccactgggggtggaacaaga
tccatgactgccatgtatggccacctgctggggctgcagaagctgaacatcctgaactgt
gccagctacatcactggcctgtcaggggccacctggaccatggctaccttgtaccgtgac
cctgactggtcctccaaaaacctggagcttgccatccttgaggcacggaggcacgtagtc
aaggacaagatgcccgctctgttcccagatcagctcctcaaattccagaaggagctgcag
cagcgcaggcaggaaggctacaaagtcaccttcacagacttctggggcctgctggtcgag
gcctgtctgggggacgagagaaatgaatgcaaactgtcagatcagagtgctgctttgtgc
cagggccagaaccccctgcccatctacctcaccgtcaatgtcaaggatgatataagcaac
caggatttcagagagtggttcgagttctccccctacgaggtgggcctgccgaagtatgga
ggcttcattcccaccgagctcttcggctccgagttcttcatggggcggctgatgaggagg
atcccagagtcgcggatgtgctacatgctaggtttgtggagcagcatcttctccctgaac
ctgctcgatgcctggaatttgtcccacaactcggaagagtttttccacaggtggacaagg
gagagagtgcatgatatcgaagacgagccacacctacctgaaatccccaaatgtgatgcc
aacatcctggacaccacggtggtgatgccagggtcatggctgtccaatactttccgcaac
atcctcacctaccgggcctttgtgtctgagttccacaacttcctgctggggctgcagctg
cacaccgactaccaccagaatggccagttcgccacgtggaaagacacggtgctagatggc
ttcccaaaccagctgacagggtccgtgaaccacttgtgcctgctggacactgcattcgtc
atcaactccagctacccgcccatcctcaggccggagagaaaagctgacctcatcatccac
ctcaattactgtgctgggtcccagacaaagcccatgaaacaaacctgcaagtactgcacc
gagcagaacatccccttccccaaatatgaggtgcaggaggaggatgataacctcaaggag
tgctacctgctggagaactcccaggaacccaatgcccccattgtgattttcttcccactc
atcaacgacaccttccaaaagtacaaggccccaggtgtggagcgaagccccgaggagctg
gagcagggccaggttgacatctatggtcccaaatctccctacaccaccaaggagctgaca
tacacggaggccgccttcgacaagctggtgaagctctccgaatataacatcctgaataac
aaggacaagctccttcaggccttgcgactggcagtagagaagaagaaacgcctgaagagc
cagtgtccccctaaagtcccaggacacccctaa
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