Physeter macrocephalus (sperm whale): 102985137
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Entry
102985137 CDS
T06011
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad04217
Necroptosis
pcad04380
Osteoclast differentiation
pcad04620
Toll-like receptor signaling pathway
pcad04621
NOD-like receptor signaling pathway
pcad04630
JAK-STAT signaling pathway
pcad04658
Th1 and Th2 cell differentiation
pcad04659
Th17 cell differentiation
pcad05145
Toxoplasmosis
pcad05160
Hepatitis C
pcad05161
Hepatitis B
pcad05162
Measles
pcad05164
Influenza A
pcad05165
Human papillomavirus infection
pcad05167
Kaposi sarcoma-associated herpesvirus infection
pcad05168
Herpes simplex virus 1 infection
pcad05169
Epstein-Barr virus infection
pcad05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102985137 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
102985137 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
102985137 (TYK2)
04621 NOD-like receptor signaling pathway
102985137 (TYK2)
04658 Th1 and Th2 cell differentiation
102985137 (TYK2)
04659 Th17 cell differentiation
102985137 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
102985137 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
102985137 (TYK2)
05160 Hepatitis C
102985137 (TYK2)
05171 Coronavirus disease - COVID-19
102985137 (TYK2)
05164 Influenza A
102985137 (TYK2)
05162 Measles
102985137 (TYK2)
05168 Herpes simplex virus 1 infection
102985137 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
102985137 (TYK2)
05169 Epstein-Barr virus infection
102985137 (TYK2)
05165 Human papillomavirus infection
102985137 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102985137 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102985137 (TYK2)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102985137 (TYK2)
Protein kinases [BR:
pcad01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102985137 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
FERM_C_FAK1
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
102985137
NCBI-ProteinID:
XP_023990066
Ensembl:
ENSPCTG00005022202
UniProt:
A0A2Y9TGK4
LinkDB
All DBs
Position
Unknown
AA seq
1188 aa
AA seq
DB search
MPLCQWGATTRGRKPDGDGAQPMATRGGLKVLLHWAGPGGGEPWVTFSEATLTAEEVCIH
IAHKVGITPPCFNLFALFDVQAQVWLPPNHVLDMSRDSSLMLYFRMRFYFRNWHGMHPQE
PAVYRCSPPRSEPSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
QNESLGMAFLHLCHLALCHGVPLEKVAKKISFKDCIPRSFRQQIRRHNALTRLRLQSIFR
KFLRAFQPGCLSQQVVMVKYLATLERLAPRFGTERVPVCHLELLAQAEGEPCYIRDGGQA
PPDPGPESAAGPPTHEVLVSGTDGIQWRLVQAESPSDGGGGGGGRIPHAGPSGKKAKAQE
VGNQPVVRPQEAPWAYFCDFQDITHVVLKDRRVSIHCQDNKCLELTLPSRAAALSLVSLV
DGYFRLTADSSHYLCHDVAPPRLVMSIQDGIHGPLLEPFVLARLQPEDGLYLIHWSTSHL
HRLILTVAQRDPAPGMKGLHLRKFPIKLQAGTVVLEGWDRSFPSVRELRVALQGCSLRAG
DDCFSLRHCCLPRPGEISNLIVTRGPRASSRPLNLSHLSFHRVRQEDITQLSHLGQGTRT
NVYEGLLRVGGGGPEEDKVDGGDPPMPGAGCEQELRVVLKVLDPSHHDIALAFYETASLM
SQVSHVHLVFVHGIYVHGSENIMVTEYVEHGPLDVWLRRERGHVPLAWKLAVAQQLASAL
SYLEDKSLVHSNVCGRNILLARLGLAEGTSPFIKLSDPGVGLSALSREERVERIPWTAPE
CLSGGANSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQHKLPEPSCPELA
TLTSQCLTYEPAQRPSFRTILRDLTQLQPQTLPDLVDVLSVNPDSPASDPTVFHKRYLKK
IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQLRTGWRREIEILRTLYHEHI
VKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFSQQICEGMAYLHAQHY
VHRDLAARNVLLDNNRLVKIGDFGLAKAVPEGHEYYCVREDGDSPVFWYAPECLKECKFY
YASDVWSFGVTMYELLTYCDSTQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPQPEK
CPCEIYCLMKNCWKAEASFRPTFQNLIPILKTVHERYQGQAPSVFSVC
NT seq
3567 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaatggggggccaccaccaggggcagaaagcccgatggggatggagct
cagcccatggccaccagaggaggcctgaaggtgcttctgcactgggccggacccggtggc
ggggagccctgggtcaccttcagcgaggccacactgactgcggaggaggtctgcatccac
attgcacacaaagtcggcatcactccaccctgcttcaatctttttgccctcttcgatgtc
caggcccaggtctggctgcctccaaaccacgtcctggatatgtccagagactcgagcctg
atgctgtacttccgcatgaggttttatttccggaactggcatggcatgcatccccaggag
ccggctgtgtaccgctgcagtcccccacggtccgagccttcctcagaacaggcagagcag
ggggtgcaactcctggaccccgcctcctttgagtacctctttgagcagggcaagcatgag
tttgtaaatgatgtggcatcgctgtgggagctgtcaagcgaggaggagatccaccacttt
cagaatgagagcctgggcatggcctttttgcacctctgccacctcgctctctgccacggt
gtcccccttgagaaggtggccaagaagatcagcttcaaggactgcatcccacgctccttc
cggcagcagatccggcggcacaatgctctgacgcggctgcgcctgcagagcatcttccgc
aagttcctgcgggccttccagccgggctgcctctcccagcaggttgtcatggtgaagtac
ctggccacactcgagcggctggcgccccgcttcggcacagagcgcgtgcccgtgtgccac
ctggagctactggcccaggccgagggggagccctgctatatccgggatggtggacaggcc
cctcccgaccccgggcccgagtcggctgccggaccccccacccacgaggtgctggtgtcg
ggcaccgacggcatccagtggcggctggtacaggcagagagtcccagcgatggtggtggt
ggtggcggcggaaggataccccatgctggcccatctgggaagaaagccaaggcccaggag
gtgggcaaccagccagtggtcagacctcaggaggccccatgggcctacttctgcgacttc
caggacatcacccacgtggtgctgaaagatcgccgcgtcagcattcattgtcaggacaac
aagtgcctggagttgaccctgccttcccgggctgcggccctgtccttggtgtcactggtg
gatggctacttccgcctgacggccgactcgagccactacctatgccatgatgtggctcct
ccacggctggtgatgagtatccaggacggtatccacggacccctgctggagccatttgtg
ctggccaggctgcagcccgaggatggcctctacctcatccactggagcaccagccacctc
caccgccttatcctcacggtggcccagcgcgacccggcacctggcatgaagggcttgcac
ctgcggaagttccccatcaagctgcaggctgggactgtcgtgctggagggctgggaccgg
tccttccccagcgtgcgcgagctgcgggttgccctgcagggctgctccctgcgggccggc
gacgactgcttttccctgcgccactgctgcctgccacggccgggagagatctccaacctc
atcgtcacgcggggacctcgggccagcagcaggccgctcaacctcagccatctcagcttc
caccgggtccgccaggaagacatcacccagctgtcccacttgggccagggcacaaggacc
aacgtgtatgagggcctcttgcgagtggggggcggaggccccgaggaggacaaggtggat
ggcggggacccccccatgcccggggcgggctgtgaacaggagctgcgagtggtactcaag
gtgctagatcccagtcaccacgacatcgccctggccttctacgagacagccagcctcatg
agccaggtctcccacgtgcacctggtcttcgtgcacggcatctatgtgcatggctccgag
aacatcatggtgacggagtacgtggagcacgggcccctggatgtgtggctgcggcgggag
aggggccacgtgcccctggcctggaagctggcagtggcccagcagctggccagcgccctc
agctacctggaagacaagagcctggttcacagcaacgtgtgtggccggaacatcctgctg
gcacggctggggctggcggagggcaccagccccttcatcaagctgagtgatcccggtgtg
ggcctgagcgccctctccagggaggaacgggtggagcggatcccctggacagcccctgag
tgcctgtccggtggagccaacagcctaagcactgcagccgacaagtggggctttggtgcc
accctcctggagatctgcttcgatggggaggcccccctgcagggccgcagcccctccgag
aaagagcgcttctaccagaagcagcacaagctgcctgagccctcgtgcccagagctggcc
acactcaccagccagtgcctgacctatgagccagcccagcggccatccttccgcaccatc
ctgcgtgacctcactcagctgcagccgcaaactcttccagatctcgttgatgtcttgtct
gtgaacccggactcaccggcgtcagatcctacggttttccacaagcgctatttgaaaaag
atccgggatctgggtgagggtcacttcggaaaggtcagcctgtactgctacgatccaacc
aatgacggcactggtgagatggtggccgtgaaggccctcaaggcaggctgcggtccccag
ctccgtacaggctggaggcgagagatcgaaatcttgcgcacactctaccacgagcacatt
gtcaagtacaagggctgctgcgaggaccaaggcgagaagtcggtacagctggtcatggag
tacgtgcccctgggcagcctccgagactacttgccccggcacaatgtcgggctggcccag
ctgctgctcttctcccagcagatctgcgagggtatggcctacctgcacgcgcagcactac
gtgcaccgagacctggccgcacgcaacgtgctgctggacaacaacaggctggtcaagatt
ggggacttcggcctcgccaaggccgtgcccgaaggccatgagtactactgtgtgcgcgag
gatggggacagtcccgtattctggtatgccccggagtgcctgaaggagtgtaagttctac
tatgcatccgacgtctggtcctttggggtcaccatgtatgagctgctgacctactgtgac
tccacccagagccccccctcgaaattcatcgagctcataggcctcacccaggggcagatg
acagtgctgaggctcactgagctgctggaacgaggggagaggctgccacagccagagaaa
tgtccctgtgagatctattgcctcatgaagaactgctggaaagcagaggcctcattccgc
ccgaccttccagaacctcatacccatcctcaaaactgtccacgagagataccaaggccag
gcaccctcagtgttcagtgtctgctga
DBGET
integrated database retrieval system
