Physeter macrocephalus (sperm whale): 102985473 Help Entry 102985473         CDS       T06011                                  Symbol TSC2 Name (RefSeq) tuberin isoform X9   KO K07207   tuberous sclerosis 2 Organism pcad  Physeter macrocephalus (sperm whale) Pathway pcad04072   Phospholipase D signaling pathway pcad04115   p53 signaling pathway pcad04140   Autophagy - animal pcad04150   mTOR signaling pathway pcad04151   PI3K-Akt signaling pathway pcad04152   AMPK signaling pathway pcad04211   Longevity regulating pathway pcad04218   Cellular senescence pcad04714   Thermogenesis pcad04910   Insulin signaling pathway pcad04919   Thyroid hormone signaling pathway pcad05163   Human cytomegalovirus infection pcad05165   Human papillomavirus infection pcad05168   Herpes simplex virus 1 infection pcad05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:pcad00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     102985473 (TSC2)    04151 PI3K-Akt signaling pathway     102985473 (TSC2)    04152 AMPK signaling pathway     102985473 (TSC2)    04150 mTOR signaling pathway     102985473 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     102985473 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     102985473 (TSC2)    04218 Cellular senescence     102985473 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102985473 (TSC2)    04919 Thyroid hormone signaling pathway     102985473 (TSC2)   09149 Aging    04211 Longevity regulating pathway     102985473 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     102985473 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     102985473 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     102985473 (TSC2)    05163 Human cytomegalovirus infection     102985473 (TSC2)    05165 Human papillomavirus infection     102985473 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:pcad01009]     102985473 (TSC2) Protein phosphatases and associated proteins [BR:pcad01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      102985473 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  102985473 NCBI-ProteinID:  XP_007100133 Ensembl:  ENSPCTG00005012251 UniProt:  A0A2Y9EE39 LinkDB All DBs Position 14:48314990..48352632 Genome browser AA seq 1792 aa AA seqDB search MAKPASKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVAKTKKFEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYHMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVTWDI LLKIVERLLQQLQSLDSPELRAIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNELRSAVRIKVLDVLSFVLLINRQFY EEELINLVVISQLSHVPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVIARSLS PPPELEERDVVVYSASLEDVKTAVLGLLVILQTKLYALPASHATRVYETLVSHIQLHYKH TYTLPIASSIRLQAFDFLLQLRADSLHRLGLPSKDGLVRFSPYCVCDYMEPERGSEKKAG GPLSPPTGPPGPAPAVPAVRLGSLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYK VLIFTSPCNVDQLSAALCSMLSGPKTLERLRSTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKEFKESSAADAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQGGPELSSDPSVHVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRVG ALDAPASHFPGSPACLGSQTAPASKPEKASASTQLPAQKEKTNLAAYVPLLTQGWAEILV RRPTGNTSWLMSLENPLSPFSSDINNTPLQELSNALMAAERFKERRDTALYKSLSVPAAG SAKPPPPPRSNTDSAVVLEEGSPGEASLPVEPPELEDFEATLGTDGHYRHAEAFSRSSST SSQEEKSFHAEELAAGGIPIERAVSSEGSRPSVELAFQPSQPLSKSSSSPELQTLQDILG DPGDKADVGRLSPEAKARSQSGILDREGASWSAPGEESQGQGPTQPEGPLPSTCPRSPSG LRPRGYTISDSAPSRRGKRVERDAFRSRAGTSNTEKVPGINPSFVFLQLYHSPFFGDESN KPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTG LGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDK KRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECNLVSLQCRKDMEGLVDT SMAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDTYPSKWIARLRHIKRLRHRIREE AHYSNASLPLMQTHPPGHAKAPTQAPVEPTPTYETGQRKRLVSSVDDFTEFV NT seq 5379 nt NT seq  +upstreamnt  +downstreamnt atggccaagccagcaagcaaagattcaggcttgaaggagaagttcaagattctattggga ctgggaactccaaggccaaatcccaggtctgcagagggcaaacagacggagtttatcatc acggcggaaatcctgagagagctgagtgttgaatgtggcctcaacaatcgcatccgggtg atagggcagatctgtgaggttgccaaaacgaagaaatttgaagagcacgcggtggaagca ctctggaaggccgtctcagacttgctgcagccagagcggccgccagaggcccggcacgcg gtgctggctctgctgaaggccatcgtgcaggggcagggggaccgcttgggcgttctcagg gccctcttctttaaggtcatcaaggattacccctctaacgaagacctccacgagagactg gaagttttcaaggccctcacggacaatgggagacacatcacctacttggaagaagagctg gctgagtttgtcctgcagtggatggacatcggcctgtcctcagaatttcttctggtgctt gtgaatttggtcaaattcaacagctgttacctcgatgaatacatcgcatccatggtccac atgatctgcctgctgtgcgtccagaccgtgtcctccgtggacatagaggtctctctgcag gtgctggatgccgtggtctgctacaactgcctgccggccgagagcctccccctgttcatt gtcaccctctgccgcaccatcaatgtcaaggagctctgtgagccttgctggaagctgatg cgcaatctcctgggcacccacctgggccacagcgccatctaccatatgtgccgcatcatg gaggacagagcctacatggaagacgccccactgctgagaggagctgtgttctttgttggc atggctctctggggagcccaccggctctactctctcaagaactccccaacatctgtgttg ccgtcattttatgaggccatgacctgtccgaacgaggtggtgtcctatgagatcgtcctc tccataaccagactcatcaagaagtaccggagggagctccaggccgtgacatgggacatc ctgctgaagattgttgaacgcctacttcagcagctccagagcctggacagcccagagctc agagccatcgtccacgacctgctgaccacggtggaagagctgtgtgatcaaaatgagttc cacggctcgcaggagagatactttgagctcgttgagagatgtgcagaccagaggcctgag tcctccctcttaaacttaataacctacagggctcagtcaatccatccagcaaaggatggc tggattcacaacctgcagttactgatggagagatttttcaggaacgaattgcgcagcgct gtgcgtatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacaggcagttctat gaggaggagctgatcaacttagtggtcatctcgcagctctcccatgtcccggaggataaa gaccaccaagtccgaaagctggccacccagttgctggtagatctggctgaaggctgccac acccaccactttaatagcctgctggacatcattgagaaggtgattgcccgctccctctct ccaccccctgagctggaggaaagggatgtggtggtgtactcggcctccttggaggatgtg aagactgcagtcctgggactcctggtcattcttcagaccaagctgtatgcccttcctgcc agccacgccacacgtgtgtacgagacgcttgtcagccatatccagctccactacaagcac acctacaccctgcccattgccagcagcatccggctgcaggctttcgacttcctcctgcag ctgcgggctgactcgctgcaccgcctgggcctgcccagcaaggatgggcttgtgaggttc agcccctactgcgtctgtgactacatggagccggagcggggctctgagaagaaggctggt ggccccctgtcacctcccactgggccccctggcccggcacctgcagtccccgccgtgcgg ctcggctcgctgccctactccctgctcttccgtgtcctgctgcagtgtttgaagcaggag actgactggaaggtgctgaagctagtgctcagcaagctgcccgagtcgctgcgctacaag gtcctcatcttcacctccccgtgtaatgttgaccagctatctgccgctctttgctccatg ctttcaggtcccaagaccctcgagcggctccgaagcaccccagaagggttctccagaacc gacctgcatctcgctgtggttcctgtgctgacagcattaatttcttaccataactacttg gacaaaaccagacagcgggagatggtgtactgcctggagcaaggcctcatctaccgttgc gccagccagtgcgtggtggccctggccatctgcagcgtggagatgcctgacatcatcatc aaggcgctgcctgtcctggtcgtgaagctcacacacatctcagccacggccagcatggcc attccactcctcgagttcctgtcgactctggccagactgcctcacctctacaggaacttc gcagcagagcagtacgccagtgtgtttgccatctccctgccgtataccaacccctccaag ttcaatcagtacattgtgtgcctggcccatcacgtcatagccatgtggttcattaggtgc cgcctgcccttccggaaagattttgttccttatatcactaagggtctgcgctccaacgtt ctcctgtcttttgatgacacccccgaaaaggacagctttagagcacggagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaattcaaggagagctctgcagccgatgccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatccagacatctctcacgagtgccagcttg gggtctgcagatgagaactcaatggcccaggctgacgacaacttgaaaaatctccacctg gagctcacagagacgtgtctggacatgatggccagatacgtgttctccaacttcacggcg gtccccaagaggtcccccgtgggagagttcctcctggcgggtggcaggaccaaaacctgg ctggttgggaacaagcttgtcaccgtgacgacgagcgtggggactgggacccgatctctg ctgggcctggactcaggagagctgcagggcggcccagagttgagctctgaccccagtgtg cacgtgagacagacaaaggaggcaccagccaagctggagtcccaggccgggcaacaggtg tgccgtggagcccgggaccgggtccgctccatgtctgggggccatggccttcgagttggt gccttggatgctccagcctcccactttcctggcagccccgcttgcctgggctcacagact gctccagccagcaagcccgagaaggcctcagccagcacccagctcccggcacagaaggag aagacaaacctggcggcttacgtccccctgctgacccagggctgggcggagatcttggtc cggagacccacagggaacaccagctggctgatgagcctggagaacccactcagtcccttc tcctcggacatcaataacacgcccctgcaggagctgtcgaatgccctaatggccgccgag cgcttcaaggagcgtcgcgacacagccctgtacaagtcgctgtcggtgccggcggccggc tcagccaagccccccccacccccacgctctaacacagactctgcggtagttctggaggag ggaagtccaggcgaggctagtttgccagtggagccccctgaactggaagactttgaggca accctaggcacagacgggcactatcgacacgctgaagctttcagcaggtcatcttcgact tccagccaggaggagaagtcgttccacgccgaggagttggctgctggggggatccccatc gagcgggccgtctcctctgagggctcccggccctctgtggagctcgccttccagccctca cagcccctgagcaagtcaagttcatcgcctgaactacagacgctgcaggacatccttggg gaccctggggacaaggctgatgtcggccggctgagccctgaggccaaggcccggtcacag tcagggatcctagacagggaaggtgcttcctggtcagccccaggcgaagagagccagggc cagggtcccacccagcctgagggtcccttgccttccacctgtccccgctcccccagtggg ctgcggcctcgaggctacactatctctgattcagccccgtcacgcaggggcaagagggtg gagagggacgccttcaggagcagagctgggacctccaataccgagaaggtgccgggtatc aaccccagctttgtgttcctgcagctctaccactcacctttcttcggtgatgagtccaac aagccaatccttttgcccaatgagtcttttgagcggtcagtgcagcttcttgaccagatc ccatcgtatgacacacacaagatcgccgtcctgtacgtgggagaaggccagagcaacagt gagctcgccatcctgtccaatgagcacggctcctacaggtacacggagttcctgacgggg ctgggcaagctcatcgagctcaaggactgccagccggacaaggtgtacctgggcggcctg gacgtgtgcggcgaggacggccagttcacctactgctggcatgacgacatcatgcaagcc gtcttccacatcgccaccctgatgcccaccaaggacgtggacaagcaccgctgtgacaag aagcgccacctgggcaacgacttcgtgtccattgtctacaacgactctggcgaggacttc aagctcggcaccatcaaaggccagttcaactttgtccacgtaatcatcaccccactggac tatgagtgcaacctggtgtcgctgcagtgcaggaaagacatggagggcctcgtggacacc agcatggccaagatcgtgtccgaccgaaacctgcccttcgtggcccgtcagatggccttg cacgcaaatatggcctcgcaggtgcaccacagccgctccaaccccaccgacacctatccc tccaagtggattgccaggctccgccacatcaagcggctccgccaccggatccgtgaggaa gcccactactcaaacgccagcctgcccctgatgcagactcaccctcctggccatgccaag gcccccacgcaggccccagttgagcccacgcccacctacgagacaggccagcggaagcgc ctcgtctcctccgtggatgacttcactgagttcgtgtga

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