Physeter macrocephalus (sperm whale): 102987099
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Entry
102987099 CDS
T06011
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X10
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad04010
MAPK signaling pathway
pcad04020
Calcium signaling pathway
pcad04022
cGMP-PKG signaling pathway
pcad04024
cAMP signaling pathway
pcad04260
Cardiac muscle contraction
pcad04261
Adrenergic signaling in cardiomyocytes
pcad04270
Vascular smooth muscle contraction
pcad04723
Retrograde endocannabinoid signaling
pcad04725
Cholinergic synapse
pcad04726
Serotonergic synapse
pcad04727
GABAergic synapse
pcad04911
Insulin secretion
pcad04912
GnRH signaling pathway
pcad04921
Oxytocin signaling pathway
pcad04924
Renin secretion
pcad04925
Aldosterone synthesis and secretion
pcad04927
Cortisol synthesis and secretion
pcad04929
GnRH secretion
pcad04934
Cushing syndrome
pcad04935
Growth hormone synthesis, secretion and action
pcad05010
Alzheimer disease
pcad05020
Prion disease
pcad05022
Pathways of neurodegeneration - multiple diseases
pcad05207
Chemical carcinogenesis - receptor activation
pcad05410
Hypertrophic cardiomyopathy
pcad05412
Arrhythmogenic right ventricular cardiomyopathy
pcad05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102987099 (CACNA1S)
04020 Calcium signaling pathway
102987099 (CACNA1S)
04024 cAMP signaling pathway
102987099 (CACNA1S)
04022 cGMP-PKG signaling pathway
102987099 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
102987099 (CACNA1S)
04929 GnRH secretion
102987099 (CACNA1S)
04912 GnRH signaling pathway
102987099 (CACNA1S)
04921 Oxytocin signaling pathway
102987099 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
102987099 (CACNA1S)
04924 Renin secretion
102987099 (CACNA1S)
04925 Aldosterone synthesis and secretion
102987099 (CACNA1S)
04927 Cortisol synthesis and secretion
102987099 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
102987099 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
102987099 (CACNA1S)
04270 Vascular smooth muscle contraction
102987099 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
102987099 (CACNA1S)
04725 Cholinergic synapse
102987099 (CACNA1S)
04726 Serotonergic synapse
102987099 (CACNA1S)
04723 Retrograde endocannabinoid signaling
102987099 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
102987099 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
102987099 (CACNA1S)
05020 Prion disease
102987099 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
102987099 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
102987099 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
102987099 (CACNA1S)
05414 Dilated cardiomyopathy
102987099 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102987099 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pcad04040
]
102987099 (CACNA1S)
Ion channels [BR:
pcad04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
102987099 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
102987099
NCBI-ProteinID:
XP_023986384
Ensembl:
ENSPCTG00005012697
UniProt:
A0A2Y9TE51
LinkDB
All DBs
Position
Unknown
AA seq
1868 aa
AA seq
DB search
MEPSPPQDEGLRKKQPKKPVPEALPRPPRALFCLTLQNPVRKACISIVEWRPFETIILLT
IFANCVALAVYLPMPEDDSSALNLGLEKLEYFFLIIFSIEAATKIIAYGFLFHQDAYLRS
GWNVLDFTIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIVKATLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDVVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYLSWITQGEVMDVDDPREGKLALEEGGSDTESLYELAGLNKVIQFIRHWRRWNRV
FRWKCHDAVKSRVFYWLVILIVALNTLSIASEHHQQPLWLTHLQDVANRVLLALFTVEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGLLEILLVESGAMTPLGISVLRCIRLLRIFKVTK
YWTSLRNLVASLLNSIRSIASLLLLLSLFVVTFALLGVQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSLMYNGVLAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERRRRKMSKGLPDKSEEEKSMAAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPISPRPRPLAELQLKEKAVPIPEASAFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRTESVRNQILGYFDIVFT
SVFTVEIALKMTAYGAFLHKGSFCRNYFNILDLVVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEEECRGYYYVYKDGDPAQMELRPRQWMHSNFHFDNVLSAMMSLFTVSTFEGWPELL
YRAIDSHEEDKGPVYNHRVEMAIFFVVYIILIAFFMMNIFVGFIIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTLCLGMQHY
NQSQQLDHVSDILNVVFTAIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGSCGNVDPDESARISSAFFRLFRVLRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMLGKIALVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGQLCDPESDYGPGEERTCGTDFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMRRQEEYYGYRPKKDTAQIQAGLR
TLEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
HMANQRPLQFTEIEMEELESPVFLEDFPQHPSTNPLARANTNNANANVAGGNSNHGNSPA
FSSIHSAGELPGETEAPATRGGASGRPRGTLGPHGKSHGERLQGQLPRRAVPGAQAPAAP
CQLVGTESLVPEERSPTPGSMPEEAPPEDGTPGCPAPAMALLIREALVRGGLDTLAADAS
FVMATGHTLAEACQMEMQEVEVAAAELLKGQETLEGVASARRCRSLGSSLGSLNQHQGSQ
ETLIPRRL
NT seq
5607 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtccccgccgcaggatgagggcctgcggaagaaacagccgaagaagcccgtt
cccgaggccctgcccaggccgccccgggccttgttctgcttgactctccagaaccccgtg
aggaaggcctgcatcagcatcgtggaatggagacccttcgagaccatcatcttactcacc
atctttgccaactgtgtggccctggccgtgtacctacccatgccggaggatgacagcagc
gctctgaacctcggcctggagaagctggagtacttcttcctcatcatcttctccatcgag
gccgccacgaagatcatcgcctacggcttcctgttccaccaggatgcctacctgcgcagc
ggctggaacgtgctggacttcaccatcgtcttcctgggcgtcttcaccgtgatcctggag
caggtcaacgtcatccagagcaacacagccccgatgagcagcaaaggcgcgggcttggac
gtcaaggctctgagggccttccgcgtgctcaggccgctccggctggtgtccggggtgccc
agcctgcaggtggtcctcaactccatcgtcaaggccacgctgcccctgttccacatcgct
ctgctggtgcttttcatggtcatcatctacgccatcatcgggctggagctgttcaagggc
aagatgcacaagacctgctacttcatcgggacggacgtcgtggccacggtggagaacgag
aagccgtcgccctgtgcccggacgggctcagggcgcccctgcaccatcaacggcagcgag
tgccggggaggctggccaggccccaaccacggcatcacccacttcgacaacttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgtcctctactgg
gtcaacgacgccatcgggaacgaatggccctggatctactttgtcaccctcatcctgctg
ggctccttcttcatcctcaacttggtgctgggcgtcctgagcggggaattcaccaaggag
cgggagaaggccaagtccaggggaaccttccagaagctgcgggagaagcagcagctagag
gaggacctccggggctacctgagctggatcacgcagggcgaggtcatggatgtggacgac
ccgagagaagggaagctggctttggaggaaggtggctctgacacagagagcctgtatgaa
ctcgcaggcttgaacaaagtcatccagtttatccgacactggaggcggtggaaccgcgtc
ttccgctggaagtgccacgatgcggtgaagtccagggtcttctactggctggtcatcctg
atcgtcgccctcaacaccctgtcgatcgcctcggagcaccaccagcagcctctctggttg
acccacctgcaagacgtcgccaaccgggtgctgctggccctgttcaccgtggagatgctg
atgaagatgtatgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggtctcctggagatcctgctggtggagtcgggagccatgaca
cccctcggcatctccgtgctgcgctgcatccgcctcctcaggatcttcaaggtcaccaag
tactggacgtctctgcgcaacctggtggcctcgctgctcaactccatccgctccatcgcc
tccctgctactgctgctctccctcttcgtcgtcaccttcgccctcctgggcgtgcagctc
ttcgggggcaggtacgactttgaggacaccgaggtgcggcgcagcaacttcgacaacttc
ccgcaggccctcatcagcgtcttccaggtgctgacaggtgaggactggaactccttgatg
tacaacggggtcctggcctacggcggcccgacctaccccggggtgctcgtctgcatctat
ttcatcatcctgttcgtctgcggcaactacatcctgctcaacgtcttcctggccatcgcg
gtagacaacctggcggaggcggagagcctgacttcggcccagaaggccaaggctgaggag
cggagacgcaggaagatgtccaaggggctcccagacaagtcagaggaggagaagtcgatg
gcggccaagaagctggagcagaaacccaagggggagggcatccccaccacggccaagctg
aagatcgatgagtttgaatccaacgtcaatgaggtgaaggacccctacccgtcagccgac
ttcccaggagatgatgaggaagacgagcccgagatcccgataagcccacgaccccgcccg
ctggccgagttgcagctgaaggagaaggcggtgcccattccagaagccagcgccttcttc
atcttcagccccaccaataagatccgcgtcctgtgccatcgcatcgtcaatgccacctgg
ttcaccaacttcatcctgctcttcatcctgctcagcagcgccgccctggctgcggaggac
cccatccggactgagtccgtgaggaaccagatccttgggtattttgacatcgtgttcacc
tctgtcttcactgtggagattgccctcaagatgaccgcctacggcgccttcctgcacaag
ggttccttctgccgcaactacttcaacatcctggacctggtggtggtggccgtgtccctc
atctccatgggactcgagtccagcgccatctccgtggtgaagatcctgagggtgctgcgg
gtgctgcgaccgctccgggccatcaacagagccaaagggctgaagcacgtggtgcagtgc
gtgttcgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttc
atgttcgcctgcatcggcgtccagctcttcaagggcaaattcttcagctgcaatgacttg
tccaagatgacagaggaggagtgcaggggctactactacgtgtacaaggatggggacccc
gcgcagatggagctgcgtccccgccagtggatgcacagcaacttccacttcgacaacgtg
ctctcggccatgatgtctctcttcacggtgtccaccttcgaggggtggcccgagctgctg
tacagggccatcgactctcacgaggaggacaagggccccgtgtacaaccaccgcgtggag
atggccatcttcttcgtcgtctacatcatcctcatcgccttcttcatgatgaacatcttc
gtgggcttcatcatcgtcaccttccaggagcagggggagaccgagtacaagaactgcgag
ctggacaagaaccagcgccagtgcgtgcagtacgccctgaaggcccgccccctgaggtgc
tacatccccaagaacccgtaccagtaccaggtgtggtacgtcgtcacctcgtcctacttc
gagtacctgatgttcgccctcatcatgctcaacacgctctgcctgggcatgcagcactac
aaccagtcccagcagctggaccacgtgtcagacatcctcaacgtggtcttcaccgccatc
ttcacgctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggggac
ccctggaatgtgtttgacttcctgattgtcatcggcagcatcatcgacgtcatcctcagt
gagattgacactttcctggcctccagcgggggactgtattgcctgggtggcagctgcggg
aacgttgaccccgacgagagcgcgcgcatctccagcgccttcttccgcctgttccgcgtc
ctgaggctgatcaagctgctgagccgcgccgagggcgtgcgcacgctgctctggaccttc
atcaagtccttccaggccctgccctacgtggctctgctcatcgtcatgctcttctttatc
tacgccgtcatcggcatgcagatgctcgggaagattgccctggtggacgggacccagatc
aaccggaacaacaacttccagaccttcccccaggccgtgttgctgctcttcaggtgtgcc
acgggggaggcgtggcaggagatcctgctggcctgcagctacggccagctgtgcgacccc
gagtcggactacggcccgggggaggagcgcacctgcggcaccgacttcgcctactactac
ttcatcagcttctacatgctctgtgccttcctgatcatcaacctctttgtggccgtcatc
atggacaacttcgactacctcacacgggactggtccatcctgggccctcatcacctggac
gagttcaaggccatctgggcagagtacgacccggaggctaagggcagaatcaaacacctg
gatgtggtgaccctgctgagaaggatccagccccctctgggctttgggaagttctgcccg
caccgggtagcgtgtaagcggctggtgggcatgaacatgcccctgaacagcgacggcacg
gtcaccttcaacgccaccctcttcgccctggtccgcacagcgctcaagatcaagacggaa
ggtaacttcgaacaggccaatgaggagctgcgggccatcatcaagaagatctggaaaagg
accagcatgaagctcctggaccaggtcatccctcctataggagatgacgaggtgacggtg
gggaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaggcgccag
gaggagtattatgggtaccggcccaagaaggacaccgcgcagatccaggccggactgcgg
accctcgaggaagaggcagcccctgagatccgccgcaccatctcgggagacctgacggcc
gaggaggagctggagagagccatggtggaggccgcgatggaggaagggatattccggagg
accggaggcctgtttggccaggtggacaacttcctggaaaggaccaactccctgcctcca
cacatggccaaccagaggcccctccagtttactgaaatagagatggaggagctggagtcg
cccgtcttcttggaggacttccctcagcatccaagcaccaaccctcttgcacgtgccaac
accaacaatgccaacgccaacgttgccggtggcaacagcaaccatggcaacagcccggca
ttttccagcatccactctgcaggggagctcccaggggagacagaggcgcctgccaccaga
ggaggagcctccggccggccccgggggaccctgggaccccacggcaagtcccacggggag
aggctgcagggacagctgccccggagggcggtacccggagctcaggcacctgccgccccc
tgccagcttgtggggacggagtctctggtgcccgaggagaggagccccaccccagggtcc
atgcccgaggaagcgccccccgaggacggtacccccgggtgcccggccccagccatggcc
ctgctgatccgagaggctctggttcgagggggcctggacaccttggcggcggatgctagc
ttcgtcatggcaacgggccacaccctggcggaagcctgccagatggaaatgcaggaagtg
gaggtggcagccgccgagcttctgaagggacaagagaccctggagggtgtggccagtgcc
cggaggtgtcggagcctcgggtcctccctgggaagcctcaaccagcatcagggctcccag
gagaccctcattccccgcaggctgtga
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integrated database retrieval system
