Physeter macrocephalus (sperm whale): 102987670
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Entry
102987670 CDS
T06011
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad04140
Autophagy - animal
pcad04141
Protein processing in endoplasmic reticulum
pcad04210
Apoptosis
pcad04932
Non-alcoholic fatty liver disease
pcad05010
Alzheimer disease
pcad05012
Parkinson disease
pcad05014
Amyotrophic lateral sclerosis
pcad05016
Huntington disease
pcad05017
Spinocerebellar ataxia
pcad05022
Pathways of neurodegeneration - multiple diseases
pcad05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102987670
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102987670
09143 Cell growth and death
04210 Apoptosis
102987670
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
102987670
05012 Parkinson disease
102987670
05014 Amyotrophic lateral sclerosis
102987670
05016 Huntington disease
102987670
05017 Spinocerebellar ataxia
102987670
05022 Pathways of neurodegeneration - multiple diseases
102987670
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102987670
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102987670
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102987670
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102987670
Protein kinases [BR:
pcad01001
]
Serine/threonine kinases: Other
IRE family
102987670
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Pkinase_fungal
Kdo
APH
PQQ_2
PQQ
Motif
Other DBs
NCBI-GeneID:
102987670
NCBI-ProteinID:
XP_028339582
Ensembl:
ENSPCTG00005018011
UniProt:
A0A455ASM5
LinkDB
All DBs
Position
Unknown
AA seq
858 aa
AA seq
DB search
MGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNA
TYFDYAAALPEDDGEYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGL
RKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPRETEAKSKLMPTLYVGKYSTSLYASP
SMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLHN
YWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVIDLVDQTSENAPTT
VSPDVEEKFAHAPPRPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSRRQQRQLQHQ
QFQKELEKIQLLQQQQLPFHPPGDVAAQDAELPDLCGQYSESSATSSPSTSPRVSNHSLH
SSGSACKAATSPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAV
KRILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDF
AHLGLEPIALLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPSAHGRIKAMISDFGLCKKL
AVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKS
LQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQ
LQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVR
DLLRAMRNKKHHYRELPEEVRETLGPLPDGFVRYFTSRFPHLLSHTYRAMELCRRERPFQ
PYYYEPPEPRPPVTPDAL
NT seq
2577 nt
NT seq
+upstream
nt +downstream
nt
atgggtaaaaagcaggacatctggtatgtcattgacctcctgactggggagaaacagcag
actttgtcatcggcctttgcggatagtctctgcccatcaacctctcttctgtatcttggg
cgaacagagtacaccatcaccatgtacgacaccaaaacccgcgagctccggtggaacgcc
acctacttcgactacgcagctgcgctgcccgaggacgacggggaatataaaatgtcccac
tttgtgtccaatggcgatgggctggtggtgaccgtggacagtgaatctggggacgtcctg
tggatccaaaactatgcttcccccgtggtggctttttacatctggcagcgggagggtctg
cggaaggtgatgcacatcaacgtcgccgtggagaccctgcgctacctgaccttcatgtcg
ggggaggtggggcgcatcaccaagtggaagtacccgttccccagggagacggaggccaag
agcaagctgatgcccaccctgtatgtggggaaatactctaccagcctctacgcttccccc
tcaatggtacacgagggggtcgccgttgtgccccgaggcagcacccttcctttgctggaa
ggaccccagaccgacggtgtcaccatcggagacaaaggggagtgtgtgatcacacccagc
acggacctgaagttcgaccctgggctcaaagggaagagcaagctcaactacctgcacaac
tactggctgctcatcggacaccacgagaccccactgtctgcgtctaccaagatgctggag
cggttccccaacaatctgcccaaacaccgggaaaatgtgattcctgctgactcagagaaa
aagagctttgaggaggttatcgacctggttgaccagacttcagaaaacgcacctaccaca
gtttctccagatgtggaagagaagttcgctcatgcccccccaaggcccgaggcccccgtg
gactccatgctcaaggacatggctaccatcatcctgagcaccttcctgctcattggctgg
gtggccttcatcatcacctaccccctgagcagacgtcagcagcggcagctccagcaccag
cagtttcagaaggaactggagaagatccagctcctgcaacagcagcagctgcccttccac
ccacctggagacgtcgcggctcaggacgccgagctcccggacttgtgcggccagtactcg
gagagctcggccaccagcagccccagcacgtcccccagagtctccaaccactcgctccac
tccagcggctccgcctgcaaggctgccaccagccccttcctggagcaggatgacgaggat
gaggaaaccagcatggtgatagttgggaaaatctcattctgtccgaaggacgtcctgggc
cacggagccgagggcacaattgtgtaccgtggcatgtttgacaaccgcgacgtggccgtc
aagaggatcctccccgagtgttttagtttcgcagaccgtgaggtccagctgctgcgagag
tcggacgagcacccaaacgtgatccgttacttctgcaccgagagggaccggcagttccag
tacatcgccatcgagctgtgcgcggccaccctgcaggagtacgtggaacagaaggacttt
gcccacctcggcctggagcccatcgccctgctgcagcagaccacctcgggcctggcccac
ctgcactccctcaacatcgttcacagagacctgaagccacacaacattctcctctccatg
cccagcgcacatggcaggatcaaggccatgatctccgacttcggcctctgtaagaagctg
gcagtgggcagacacagcttcagccgccgctcaggggtgcccggcacagaaggctggatc
gccccagagatgctgagcgaagactgcaaggagaaccccacctacacggtggacatcttc
tctgcgggctgcgtcttttactacgtgatatctgagggcagccatccttttggcaagtcc
ctgcagcggcaggccaacatcctcctgggcgcctgcagcctggactgcctgcaccctgag
aagcacgaagacgttattgcccgggagttaatagagaagatgattgcaatggatcctcag
aagcgcccatcagcgaagcatgtgctgaaacacccgttcttctggagcctagaaaagcag
ctccagttcttccaggacgtgagtgaccggatagagaaggagtccctagacggcccgata
gtgaagcagctggagcgcggcgggcgggctgtggtgaagatggactggagggagaacatc
actgtccccctccagacagatctgcgtaaattcagaacctataaaggcggctctgtccga
gatctcctccgggccatgagaaataagaagcaccactaccgggagctgcccgaggaggtg
cgggagacgctgggcccccttcccgacggcttcgtgcgctacttcacctcgcgcttcccc
cacctcctctcccacacgtaccgtgccatggagctgtgccggcgcgagaggcccttccag
ccctactactacgagccccccgagccccggcccccagtgactccagacgccctctga
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