Physeter macrocephalus (sperm whale): 102988102
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Entry
102988102 CDS
T06011
Symbol
FH
Name
(RefSeq) fumarate hydratase, mitochondrial
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00020
Citrate cycle (TCA cycle)
pcad00620
Pyruvate metabolism
pcad01100
Metabolic pathways
pcad01200
Carbon metabolism
pcad04934
Cushing syndrome
pcad05200
Pathways in cancer
pcad05211
Renal cell carcinoma
Module
pcad_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pcad_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
102988102 (FH)
00620 Pyruvate metabolism
102988102 (FH)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102988102 (FH)
09162 Cancer: specific types
05211 Renal cell carcinoma
102988102 (FH)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102988102 (FH)
Enzymes [BR:
pcad01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
102988102 (FH)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
Motif
Other DBs
NCBI-GeneID:
102988102
NCBI-ProteinID:
XP_007119566
Ensembl:
ENSPCTG00005001704
UniProt:
A0A2Y9FCK6
LinkDB
All DBs
Position
4:57626397..57669694
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AA seq
510 aa
AA seq
DB search
MDRALRLLARSRFLSRAPASDPRPGPGPAGAAVLLLRPPNVVRMASQNSFRIEYDTFGEL
KVPNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDPKIANAI
MKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDH
VNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHAQDAV
PLTLGQEFSGYVQQVKYATTRIKGAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAAL
TGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPE
NEPGSSIMPGKVNPTQCEAVTMVAAQVMGNHVAITIGGSSGHFELNVFKPLMIKNVLHSA
RLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGS
TLKATAIELGYLTAEQFDEWVKPKDMLGPK
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atggatcgcgcgctacgactcctcgcgcgttcgcgtttcctctcgcgcgctccagcttcc
gacccccgccctggccccggcccggctggcgcggcagtccttctgcttcggcctccgaac
gtcgttcgaatggcaagccaaaattcttttcggatagaatatgatacctttggtgagctc
aaggtcccaaatgataagtattatggagcccagactgtgagatctacaatgaactttaag
attggaggggtgacagaacgcatgccaatcccagttattaaagcatttggcatcttgaag
cgagcagctgctgaagtaaatcaggattatggtcttgatccaaagattgctaatgcaata
atgaaggcagcagatgaggtagctgaaggtaaattaaatgatcattttcctctcgtggta
tggcagactggatcaggaacccagacaaatatgaatgtaaatgaagtcattagcaataga
gcaattgaaatgctaggaggtgaacttggcagcaagaaacccgtgcatcccaacgatcat
gttaataaaagtcagagctcaaatgatacttttcccacagcaatgcatattgctgctgca
atagaagttcatgaagtactgctaccaggactacagaagctacatgatgcccttgatgca
aaatccaaagaatttgcccagatcatcaaaattgggcgtactcatgcacaggatgctgtt
ccacttactcttgggcaggaatttagtggttatgttcaacaagtgaaatatgcaacaaca
agaataaaaggtgccatgccaagaatctacgagctcgcagctgggggcactgctgtcggt
actggcttaaatactagaattggctttgcagaaaaggttgctgcaaaagtggctgcactc
acaggcttgcctttcgtcacagctccaaataaatttgaagctttggctgctcatgatgct
ttggttgaactcagtggagccatgaacactactgcttgcagtctgatgaagattgcaaat
gatattcgttttctgggttctggtcctcgctcaggtctgggagaactgattttgcctgaa
aatgaaccaggaagcagtatcatgccaggcaaggtgaaccccacccagtgtgaggcagtg
accatggttgcagcccaggtcatgggcaatcatgtcgccatcaccattggaggcagcagt
ggacattttgagttgaatgttttcaagccattgatgattaaaaatgtgttacactcagcc
agactgttgggggatgcatcagtttccttcacagaaaactgtgtggtgggaatccaggcc
aacacagaaaggatcaacaagctaatgaatgagtccctaatgttggtgacagctcttaat
cctcatatagggtatgacaaagcagccaagattgctaagactgcacacaaaaatggatcg
accttaaaggcaactgctattgaacttggctatctcacagcagagcagtttgatgaatgg
gtaaaacctaaggacatgctgggtccaaagtga
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