Physeter macrocephalus (sperm whale): 102989074
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Entry
102989074 CDS
T06011
Symbol
MAPK3
Name
(RefSeq) mitogen-activated protein kinase 3
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad01522
Endocrine resistance
pcad01524
Platinum drug resistance
pcad04010
MAPK signaling pathway
pcad04012
ErbB signaling pathway
pcad04014
Ras signaling pathway
pcad04015
Rap1 signaling pathway
pcad04022
cGMP-PKG signaling pathway
pcad04024
cAMP signaling pathway
pcad04062
Chemokine signaling pathway
pcad04066
HIF-1 signaling pathway
pcad04068
FoxO signaling pathway
pcad04071
Sphingolipid signaling pathway
pcad04072
Phospholipase D signaling pathway
pcad04114
Oocyte meiosis
pcad04140
Autophagy - animal
pcad04148
Efferocytosis
pcad04150
mTOR signaling pathway
pcad04151
PI3K-Akt signaling pathway
pcad04210
Apoptosis
pcad04218
Cellular senescence
pcad04261
Adrenergic signaling in cardiomyocytes
pcad04270
Vascular smooth muscle contraction
pcad04350
TGF-beta signaling pathway
pcad04360
Axon guidance
pcad04370
VEGF signaling pathway
pcad04371
Apelin signaling pathway
pcad04380
Osteoclast differentiation
pcad04510
Focal adhesion
pcad04520
Adherens junction
pcad04540
Gap junction
pcad04550
Signaling pathways regulating pluripotency of stem cells
pcad04611
Platelet activation
pcad04613
Neutrophil extracellular trap formation
pcad04620
Toll-like receptor signaling pathway
pcad04621
NOD-like receptor signaling pathway
pcad04625
C-type lectin receptor signaling pathway
pcad04650
Natural killer cell mediated cytotoxicity
pcad04657
IL-17 signaling pathway
pcad04658
Th1 and Th2 cell differentiation
pcad04659
Th17 cell differentiation
pcad04660
T cell receptor signaling pathway
pcad04662
B cell receptor signaling pathway
pcad04664
Fc epsilon RI signaling pathway
pcad04666
Fc gamma R-mediated phagocytosis
pcad04668
TNF signaling pathway
pcad04713
Circadian entrainment
pcad04720
Long-term potentiation
pcad04722
Neurotrophin signaling pathway
pcad04723
Retrograde endocannabinoid signaling
pcad04724
Glutamatergic synapse
pcad04725
Cholinergic synapse
pcad04726
Serotonergic synapse
pcad04730
Long-term depression
pcad04810
Regulation of actin cytoskeleton
pcad04910
Insulin signaling pathway
pcad04912
GnRH signaling pathway
pcad04914
Progesterone-mediated oocyte maturation
pcad04915
Estrogen signaling pathway
pcad04916
Melanogenesis
pcad04917
Prolactin signaling pathway
pcad04919
Thyroid hormone signaling pathway
pcad04921
Oxytocin signaling pathway
pcad04926
Relaxin signaling pathway
pcad04928
Parathyroid hormone synthesis, secretion and action
pcad04929
GnRH secretion
pcad04930
Type II diabetes mellitus
pcad04933
AGE-RAGE signaling pathway in diabetic complications
pcad04934
Cushing syndrome
pcad04935
Growth hormone synthesis, secretion and action
pcad04960
Aldosterone-regulated sodium reabsorption
pcad05010
Alzheimer disease
pcad05020
Prion disease
pcad05022
Pathways of neurodegeneration - multiple diseases
pcad05034
Alcoholism
pcad05132
Salmonella infection
pcad05133
Pertussis
pcad05135
Yersinia infection
pcad05140
Leishmaniasis
pcad05142
Chagas disease
pcad05145
Toxoplasmosis
pcad05152
Tuberculosis
pcad05160
Hepatitis C
pcad05161
Hepatitis B
pcad05163
Human cytomegalovirus infection
pcad05164
Influenza A
pcad05165
Human papillomavirus infection
pcad05166
Human T-cell leukemia virus 1 infection
pcad05167
Kaposi sarcoma-associated herpesvirus infection
pcad05170
Human immunodeficiency virus 1 infection
pcad05171
Coronavirus disease - COVID-19
pcad05200
Pathways in cancer
pcad05203
Viral carcinogenesis
pcad05205
Proteoglycans in cancer
pcad05206
MicroRNAs in cancer
pcad05207
Chemical carcinogenesis - receptor activation
pcad05208
Chemical carcinogenesis - reactive oxygen species
pcad05210
Colorectal cancer
pcad05211
Renal cell carcinoma
pcad05212
Pancreatic cancer
pcad05213
Endometrial cancer
pcad05214
Glioma
pcad05215
Prostate cancer
pcad05216
Thyroid cancer
pcad05218
Melanoma
pcad05219
Bladder cancer
pcad05220
Chronic myeloid leukemia
pcad05221
Acute myeloid leukemia
pcad05223
Non-small cell lung cancer
pcad05224
Breast cancer
pcad05225
Hepatocellular carcinoma
pcad05226
Gastric cancer
pcad05230
Central carbon metabolism in cancer
pcad05231
Choline metabolism in cancer
pcad05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pcad05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
102989074 (MAPK3)
04015 Rap1 signaling pathway
102989074 (MAPK3)
04350 TGF-beta signaling pathway
102989074 (MAPK3)
04668 TNF signaling pathway
102989074 (MAPK3)
04066 HIF-1 signaling pathway
102989074 (MAPK3)
04068 FoxO signaling pathway
102989074 (MAPK3)
04072 Phospholipase D signaling pathway
102989074 (MAPK3)
04071 Sphingolipid signaling pathway
102989074 (MAPK3)
04024 cAMP signaling pathway
102989074 (MAPK3)
04022 cGMP-PKG signaling pathway
102989074 (MAPK3)
04151 PI3K-Akt signaling pathway
102989074 (MAPK3)
04150 mTOR signaling pathway
102989074 (MAPK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102989074 (MAPK3)
04148 Efferocytosis
102989074 (MAPK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102989074 (MAPK3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102989074 (MAPK3)
04613 Neutrophil extracellular trap formation
102989074 (MAPK3)
04620 Toll-like receptor signaling pathway
102989074 (MAPK3)
04650 Natural killer cell mediated cytotoxicity
102989074 (MAPK3)
04660 T cell receptor signaling pathway
102989074 (MAPK3)
04658 Th1 and Th2 cell differentiation
102989074 (MAPK3)
04659 Th17 cell differentiation
102989074 (MAPK3)
04657 IL-17 signaling pathway
102989074 (MAPK3)
04662 B cell receptor signaling pathway
102989074 (MAPK3)
04664 Fc epsilon RI signaling pathway
102989074 (MAPK3)
04666 Fc gamma R-mediated phagocytosis
102989074 (MAPK3)
04062 Chemokine signaling pathway
102989074 (MAPK3)
09152 Endocrine system
04929 GnRH secretion
102989074 (MAPK3)
04915 Estrogen signaling pathway
102989074 (MAPK3)
04917 Prolactin signaling pathway
102989074 (MAPK3)
04921 Oxytocin signaling pathway
102989074 (MAPK3)
04926 Relaxin signaling pathway
102989074 (MAPK3)
04935 Growth hormone synthesis, secretion and action
102989074 (MAPK3)
04919 Thyroid hormone signaling pathway
102989074 (MAPK3)
04928 Parathyroid hormone synthesis, secretion and action
102989074 (MAPK3)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
102989074 (MAPK3)
09156 Nervous system
04724 Glutamatergic synapse
102989074 (MAPK3)
04725 Cholinergic synapse
102989074 (MAPK3)
04726 Serotonergic synapse
102989074 (MAPK3)
04720 Long-term potentiation
102989074 (MAPK3)
04730 Long-term depression
102989074 (MAPK3)
04723 Retrograde endocannabinoid signaling
102989074 (MAPK3)
04722 Neurotrophin signaling pathway
102989074 (MAPK3)
09158 Development and regeneration
04360 Axon guidance
102989074 (MAPK3)
04380 Osteoclast differentiation
102989074 (MAPK3)
09159 Environmental adaptation
04713 Circadian entrainment
102989074 (MAPK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102989074 (MAPK3)
05206 MicroRNAs in cancer
102989074 (MAPK3)
05205 Proteoglycans in cancer
102989074 (MAPK3)
05207 Chemical carcinogenesis - receptor activation
102989074 (MAPK3)
05208 Chemical carcinogenesis - reactive oxygen species
102989074 (MAPK3)
05203 Viral carcinogenesis
102989074 (MAPK3)
05230 Central carbon metabolism in cancer
102989074 (MAPK3)
05231 Choline metabolism in cancer
102989074 (MAPK3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102989074 (MAPK3)
09162 Cancer: specific types
05210 Colorectal cancer
102989074 (MAPK3)
05212 Pancreatic cancer
102989074 (MAPK3)
05225 Hepatocellular carcinoma
102989074 (MAPK3)
05226 Gastric cancer
102989074 (MAPK3)
05214 Glioma
102989074 (MAPK3)
05216 Thyroid cancer
102989074 (MAPK3)
05221 Acute myeloid leukemia
102989074 (MAPK3)
05220 Chronic myeloid leukemia
102989074 (MAPK3)
05218 Melanoma
102989074 (MAPK3)
05211 Renal cell carcinoma
102989074 (MAPK3)
05219 Bladder cancer
102989074 (MAPK3)
05215 Prostate cancer
102989074 (MAPK3)
05213 Endometrial cancer
102989074 (MAPK3)
05224 Breast cancer
102989074 (MAPK3)
05223 Non-small cell lung cancer
102989074 (MAPK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102989074 (MAPK3)
05170 Human immunodeficiency virus 1 infection
102989074 (MAPK3)
05161 Hepatitis B
102989074 (MAPK3)
05160 Hepatitis C
102989074 (MAPK3)
05171 Coronavirus disease - COVID-19
102989074 (MAPK3)
05164 Influenza A
102989074 (MAPK3)
05163 Human cytomegalovirus infection
102989074 (MAPK3)
05167 Kaposi sarcoma-associated herpesvirus infection
102989074 (MAPK3)
05165 Human papillomavirus infection
102989074 (MAPK3)
09171 Infectious disease: bacterial
05135 Yersinia infection
102989074 (MAPK3)
05133 Pertussis
102989074 (MAPK3)
05152 Tuberculosis
102989074 (MAPK3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102989074 (MAPK3)
05140 Leishmaniasis
102989074 (MAPK3)
05142 Chagas disease
102989074 (MAPK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
102989074 (MAPK3)
05020 Prion disease
102989074 (MAPK3)
05022 Pathways of neurodegeneration - multiple diseases
102989074 (MAPK3)
09165 Substance dependence
05034 Alcoholism
102989074 (MAPK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102989074 (MAPK3)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102989074 (MAPK3)
04933 AGE-RAGE signaling pathway in diabetic complications
102989074 (MAPK3)
04934 Cushing syndrome
102989074 (MAPK3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102989074 (MAPK3)
01524 Platinum drug resistance
102989074 (MAPK3)
01522 Endocrine resistance
102989074 (MAPK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102989074 (MAPK3)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pcad03036
]
102989074 (MAPK3)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pcad04147
]
102989074 (MAPK3)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
102989074 (MAPK3)
Protein kinases [BR:
pcad01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
102989074 (MAPK3)
Chromosome and associated proteins [BR:
pcad03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
102989074 (MAPK3)
Exosome [BR:
pcad04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
102989074 (MAPK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
102989074
NCBI-ProteinID:
XP_023979485
Ensembl:
ENSPCTG00005014316
UniProt:
A0A2Y9SSQ5
LinkDB
All DBs
Position
Unknown
AA seq
382 aa
AA seq
DB search
MAAAAAAAAQGGGGGEPRGTDGVGPGVPGEVEIVKGQPFDVGPRYTQLQYIGEGAYGMVS
SAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRD
VYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTT
CDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAE
MLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFP
KSDPKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPK
ERLKELIFQETARFQPGVLEAP
NT seq
1149 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggcggcggcggctcaggggggcgggggcggggagccccggggaact
gatggggtcggcccgggggtcccgggggaggtagagatagtaaaggggcagccgttcgac
gtgggcccgcgctacacgcagctgcagtacatcggcgagggcgcgtatggcatggtcagc
tcagcttacgaccacgtgcgcaagactcgagtggccatcaagaaaatcagcccctttgag
catcagacctactgccagcgtacattgcgagagatccagatcttgctgcgcttccgccat
gagaacgtcatcggcatccgagacattctgcgggcacccaccctggaagccatgagggat
gtctacattgtgcaagacctgatggagacagacctgtacaagttgcttaaaagccagcag
ctgagcaacgaccacatctgctacttcctctaccaaatcctgcggggcctcaagtatatc
cactccgccaacgtgctccaccgggatttaaagccctccaacctgctcatcaacaccacc
tgcgaccttaagatctgtgattttggtcttgcccggattgccgatcctgagcacgaccac
actggctttctgacggaatacgtggccacacgctggtaccgggccccagagatcatgctt
aactccaagggctacaccaagtccatcgacatctggtctgtgggctgcattctggctgag
atgctctccaaccggcccatcttcccgggcaagcactacctggaccagctcaatcacatt
ctgggtatcctgggctccccctcccaggaggacctgaattgtatcatcaacatgaaagcc
cgaaactacctacagtctctaccctccaagaccaaggtggcctgggccaagctttttccc
aagtcggaccccaaagctcttgacctgctggaccggatgttgacctttaaccccaacaaa
cggatcacagtggaagaagcactggctcacccctacctggagcagtactatgacccaaca
gatgagccagtggccgaggaacctttcaccttcgacatggagctggatgatctacccaag
gagcggctgaaggagctcatcttccaggagacagcccgtttccagcctggggtgctggag
gccccctaa
DBGET
integrated database retrieval system