KEGG   Physeter macrocephalus (sperm whale): 102989111
Entry
102989111         CDS       T06011                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad01522  Endocrine resistance
pcad04010  MAPK signaling pathway
pcad04015  Rap1 signaling pathway
pcad04068  FoxO signaling pathway
pcad04071  Sphingolipid signaling pathway
pcad04114  Oocyte meiosis
pcad04148  Efferocytosis
pcad04218  Cellular senescence
pcad04261  Adrenergic signaling in cardiomyocytes
pcad04370  VEGF signaling pathway
pcad04380  Osteoclast differentiation
pcad04550  Signaling pathways regulating pluripotency of stem cells
pcad04611  Platelet activation
pcad04613  Neutrophil extracellular trap formation
pcad04620  Toll-like receptor signaling pathway
pcad04621  NOD-like receptor signaling pathway
pcad04622  RIG-I-like receptor signaling pathway
pcad04625  C-type lectin receptor signaling pathway
pcad04657  IL-17 signaling pathway
pcad04658  Th1 and Th2 cell differentiation
pcad04659  Th17 cell differentiation
pcad04660  T cell receptor signaling pathway
pcad04664  Fc epsilon RI signaling pathway
pcad04668  TNF signaling pathway
pcad04670  Leukocyte transendothelial migration
pcad04714  Thermogenesis
pcad04722  Neurotrophin signaling pathway
pcad04723  Retrograde endocannabinoid signaling
pcad04728  Dopaminergic synapse
pcad04750  Inflammatory mediator regulation of TRP channels
pcad04912  GnRH signaling pathway
pcad04914  Progesterone-mediated oocyte maturation
pcad04917  Prolactin signaling pathway
pcad04926  Relaxin signaling pathway
pcad04932  Non-alcoholic fatty liver disease
pcad04933  AGE-RAGE signaling pathway in diabetic complications
pcad04935  Growth hormone synthesis, secretion and action
pcad04936  Alcoholic liver disease
pcad05014  Amyotrophic lateral sclerosis
pcad05020  Prion disease
pcad05022  Pathways of neurodegeneration - multiple diseases
pcad05132  Salmonella infection
pcad05133  Pertussis
pcad05135  Yersinia infection
pcad05140  Leishmaniasis
pcad05142  Chagas disease
pcad05145  Toxoplasmosis
pcad05152  Tuberculosis
pcad05161  Hepatitis B
pcad05163  Human cytomegalovirus infection
pcad05167  Kaposi sarcoma-associated herpesvirus infection
pcad05169  Epstein-Barr virus infection
pcad05170  Human immunodeficiency virus 1 infection
pcad05171  Coronavirus disease - COVID-19
pcad05205  Proteoglycans in cancer
pcad05208  Chemical carcinogenesis - reactive oxygen species
pcad05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pcad05415  Diabetic cardiomyopathy
pcad05417  Lipid and atherosclerosis
pcad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102989111 (MAPK14)
   04015 Rap1 signaling pathway
    102989111 (MAPK14)
   04370 VEGF signaling pathway
    102989111 (MAPK14)
   04668 TNF signaling pathway
    102989111 (MAPK14)
   04068 FoxO signaling pathway
    102989111 (MAPK14)
   04071 Sphingolipid signaling pathway
    102989111 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102989111 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    102989111 (MAPK14)
   04218 Cellular senescence
    102989111 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102989111 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102989111 (MAPK14)
   04613 Neutrophil extracellular trap formation
    102989111 (MAPK14)
   04620 Toll-like receptor signaling pathway
    102989111 (MAPK14)
   04621 NOD-like receptor signaling pathway
    102989111 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    102989111 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    102989111 (MAPK14)
   04660 T cell receptor signaling pathway
    102989111 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    102989111 (MAPK14)
   04659 Th17 cell differentiation
    102989111 (MAPK14)
   04657 IL-17 signaling pathway
    102989111 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    102989111 (MAPK14)
   04670 Leukocyte transendothelial migration
    102989111 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102989111 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    102989111 (MAPK14)
   04917 Prolactin signaling pathway
    102989111 (MAPK14)
   04926 Relaxin signaling pathway
    102989111 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    102989111 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102989111 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    102989111 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    102989111 (MAPK14)
   04722 Neurotrophin signaling pathway
    102989111 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102989111 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102989111 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    102989111 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102989111 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    102989111 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102989111 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102989111 (MAPK14)
   05161 Hepatitis B
    102989111 (MAPK14)
   05171 Coronavirus disease - COVID-19
    102989111 (MAPK14)
   05163 Human cytomegalovirus infection
    102989111 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102989111 (MAPK14)
   05169 Epstein-Barr virus infection
    102989111 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102989111 (MAPK14)
   05135 Yersinia infection
    102989111 (MAPK14)
   05133 Pertussis
    102989111 (MAPK14)
   05152 Tuberculosis
    102989111 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102989111 (MAPK14)
   05140 Leishmaniasis
    102989111 (MAPK14)
   05142 Chagas disease
    102989111 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102989111 (MAPK14)
   05020 Prion disease
    102989111 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    102989111 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102989111 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    102989111 (MAPK14)
   05415 Diabetic cardiomyopathy
    102989111 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102989111 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    102989111 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102989111 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102989111 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcad01001]
    102989111 (MAPK14)
Enzymes [BR:pcad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102989111 (MAPK14)
Protein kinases [BR:pcad01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102989111 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 102989111
NCBI-ProteinID: XP_023977530
Ensembl: ENSPCTG00005019201
UniProt: A0A2Y9SMC1
LinkDB
Position
18:70763585..70841555
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctatcggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccaaaacctgtccccggtgggctccggcgcctatggctccgtgtgtgct
gcttttgacacaaaaactgggttacgtgttgcagtgaagaagctatccagaccatttcag
tccattattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgttttcacacctgcaaggtctctggaggaattcaat
gatgtgtacctggtgacccatctcatgggggcagatctgaacaacattgtgaaatgtcag
aagcttacggatgaccacgttcaattccttatctaccagattctccgaggtctcaagtat
atacattcagccgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcttggattttggactggctcgacatacagatgatgagatgaca
ggttatgtagccactaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acattgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgagcttttgaagaaaatctcctcagagtctgcaagaaactacattcag
tctttgacccagatgccaaagatgaactttgcaaatgtatttattggtgccaatcccttg
gctgtcgacttgctggagaagatgcttgtattggactcagataagagaattacagcagcc
caagcccttgcacatgcctactttgcccagtaccatgatcctgatgatgaaccggtggct
gatccttacgatcagtcttttgaaagcagggacctccttatagatgaatggaaaagcctg
acctacgatgaagtcatcagctttgtgccaccgccccttgaccaagaagagatggagtct
tga

DBGET integrated database retrieval system