Physeter macrocephalus (sperm whale): 102989553
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Entry
102989553 CDS
T06011
Symbol
PDE10A
Name
(RefSeq) LOW QUALITY PROTEIN: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00230
Purine metabolism
pcad01100
Metabolic pathways
pcad04024
cAMP signaling pathway
pcad05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102989553 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
102989553 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
102989553 (PDE10A)
Enzymes [BR:
pcad01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
102989553 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
102989553 (PDE10A)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD
SpoVT_C
DUF7334
Motif
Other DBs
NCBI-GeneID:
102989553
NCBI-ProteinID:
XP_054943381
Ensembl:
ENSPCTG00005002171
UniProt:
A0A9W2WVW5
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All DBs
Position
10:3417883..3714532
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AA seq
1022 aa
AA seq
DB search
MAGPVEPLVPRPXGPLPAAGDEPGPGKLRPQPGGSAAGGGXAAVQGPAPESPGRRRAERA
VPARPPSSAGRASPAGGAGXAARAPSALAFSAPVRSSTPSSFYFWPPPPPPPPSLPPSSS
AVHFPARLPGREGXGGGDAGGGGGGGQEAAPLSGPPGSSHRGGGGRRRLFVSPALQGSLL
PARAGPXPGPGPGPGPGPGLGGGGRTPRRPRGAGAALAAASPLLFGSDMEDGPSNNASCF
RRLTECFLSPSLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKPEDESSPKE
VSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYGLSSIIKIATKADGFALYFLGECNN
SLCVFTPPGIKEGKPRLIPAGPIAQGTTTSAYVAKSRKTLLVEDILGDERFPRGTGLESG
TRIQSVLCLPIVTAIGDLIGILELHRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRG
LAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSD
LFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGY
TTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIR
HSECIYRVTMEKLSYHSICTAEEWQGLMHFNLPARLCKEIELFHFDIGPFENMWPGIFVY
MVHRSCGTACFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNSHGLFSELE
RKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFS
TLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTA
CDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNA
VAIPCYTTLTQIFPPTEPLLKACRNNLSQWEKVIRGEESAVWISNPPAAQGTSEKLPVKI
DD
NT seq
3069 nt
NT seq
+upstream
nt +downstream
nt
atggccggccccgtggagccgctcgttccccgccccncaggccccctgcccgcggccggg
gacgagcccggccccggcaaactccgcccgcagcccgggggcagcgcagccggcggggga
ngcgcggcggtccagggcccggcccccgagtcgcctggtcgccgccgggccgagcgcgcc
gtgcccgcgcgtcccccctcgtccgcaggccgcgccagccccgcggggggcgccggcngc
gcggcccgcgctccctccgcgctcgccttctccgcccctgtccgctcctccactccatct
tccttttacttctggccgccgccccctccgccccctccttctcttcccccctcctcatct
gccgttcacttccccgcgcgtctcccaggaagggagggcngcggcggcggcgatgctggc
ggaggaggaggaggaggacaagaggcagctcccttgagcggcccccccggcagcagtcac
cgcggcggcggcgggcggcggcggctcttcgtctcccctgcgctccagggctcgctgctg
ccagctcgcgccgggccnngccccggccccggccccggccccggccccggccccggcctc
ggcggcggcggccgaaccccgcggcggccgcgaggcgccggcgccgccctcgccgccgcg
tccccgctgcttttcggttccgacatggaagatggaccctctaataatgcgagctgcttc
cgaaggctgacggagtgtttcctgagccccagtttgacagatgaaaaagtgaaggcatat
ctttctcttcacccccaggtattagatgaatttgtatctgaaagtgttagtgcagagact
gtagaaaaatggctgaagaggaaaaacaacaaaccagaagatgaatcatctcctaaggaa
gtcagcaggtatcaagatacgaacatgcagggagttgtgtacgagctaaacagctatata
gaacagcggctggatacgggaggggacaaccagctgctcctctatgggctgagcagcatt
attaaaatcgccacaaaagctgatggatttgcactgtatttccttggagagtgtaataat
agcctttgtgtgtttaccccacctggaatcaaggaaggaaaacccaggctcatccctgct
gggcccatcgcccagggcaccaccacctccgcctacgtggcgaagtccagaaaaacgttg
ctagtagaagacatccttggggatgaacgatttccaagaggtaccggactggaatcaggg
acgcgtatccagtctgttctctgtttgcccatcgtcacggcgatcggtgatttgatcggc
atccttgagctgcaccggcactggggcaaagaagccttctgtctgagtcatcaggaggtt
gcaacagcaaatcttgcctgggcttcggtagccatacatcaggttcaggtatgcagaggt
ctcgccaaacagactgaattgaatgactttctactcgacgtatcaaaaacgtattttgat
aacatagttgcaatagattctctacttgaacacataatgatatatgcaaaaaacctggtg
aacgccgatcgttgtgcccttttccaggtggaccataagaacaaggagttatattcagac
cttttcgatatcggagaggaaaaggaaggaaaacctgtcttcaagaagaccaaagaaata
agattttcaattgagaaaggaattgctggtcaagtagcaagaacaggggaagttctgaac
attccagatgcctatgctgacccacgctttaacagagaggtggacctgtacacaggctac
acgacccggaacatcctgtgcatgcccatcgtgagtcggggcagcgtgatcggcgtggtg
cagatggtgaacaaaatcagcggcagtgccttctctaagacggacgaaaacaacttcaaa
atgtttgctgtcttttgtgctttagccttacactgtgccaatatgtatcatagaattcgt
cattcggagtgcatttaccgggtcaccatggagaagctgtcctatcatagcatttgtact
gcagaggaatggcaaggcctcatgcatttcaaccttcccgcccgtctttgcaaagaaatt
gaattgttccactttgacattggcccctttgaaaacatgtggcctggaattttcgtctac
atggtccaccggtcctgtgggacagcctgctttgagcttgaaaaattgtgtcgttttatc
atgtctgtgaagaaaaactatcgtcgggtcccttaccacaactggaagcacgcggtcacg
gtggcacactgcatgtacgccatactccagaacagccacgggctcttcagcgaactcgag
cgcaagggactgctaattgcgtgtctgtgccatgacctggaccacaggggcttcagtaac
agctacctgcagaaattcgaccaccccctcgcagcactgtactccacgtcgaccatggag
caacaccacttctcccagaccgtttccatccttcagttggaggggcacaatatcttctcc
accctgagctccagtgaatatgaacaggtgcttgagatcatccgcaaagccatcattgcc
acagaccttgcattatactttggaaacaggaaacagttggaagagatgtaccagaccgga
tcgctaaaccttaataatcaatcacatagagaccgtgtcattggtttgatgatgactgcc
tgtgatctttgttctgtgacaaagctgtggccggtaacaaaattgacggcaaacgatata
tatgcagaattctgggctgagggtgatgaaatgaagaagctgggaatacagcctattccc
atgatggacagagacaagaaagacgaagtcccacaaggccagcttggattctacaatgcc
gtggccattccctgctacacgactctcacccagatcttcccgcctacagagcctctcctg
aaagcctgcaggaataacctgagccagtgggagaaggtgattcgaggggaggagagtgcc
gtgtggatctcgaacccgccggcggcccaggggacctcggagaagctgcccgtgaagatc
gatgactga
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