Physeter macrocephalus (sperm whale): 102990192
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Entry
102990192 CDS
T06011
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad01522
Endocrine resistance
pcad01524
Platinum drug resistance
pcad04010
MAPK signaling pathway
pcad04012
ErbB signaling pathway
pcad04020
Calcium signaling pathway
pcad04066
HIF-1 signaling pathway
pcad04151
PI3K-Akt signaling pathway
pcad04510
Focal adhesion
pcad04520
Adherens junction
pcad04530
Tight junction
pcad05200
Pathways in cancer
pcad05205
Proteoglycans in cancer
pcad05206
MicroRNAs in cancer
pcad05212
Pancreatic cancer
pcad05213
Endometrial cancer
pcad05215
Prostate cancer
pcad05219
Bladder cancer
pcad05223
Non-small cell lung cancer
pcad05224
Breast cancer
pcad05226
Gastric cancer
pcad05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102990192 (ERBB2)
04012 ErbB signaling pathway
102990192 (ERBB2)
04066 HIF-1 signaling pathway
102990192 (ERBB2)
04020 Calcium signaling pathway
102990192 (ERBB2)
04151 PI3K-Akt signaling pathway
102990192 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102990192 (ERBB2)
04520 Adherens junction
102990192 (ERBB2)
04530 Tight junction
102990192 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102990192 (ERBB2)
05206 MicroRNAs in cancer
102990192 (ERBB2)
05205 Proteoglycans in cancer
102990192 (ERBB2)
05230 Central carbon metabolism in cancer
102990192 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
102990192 (ERBB2)
05226 Gastric cancer
102990192 (ERBB2)
05219 Bladder cancer
102990192 (ERBB2)
05215 Prostate cancer
102990192 (ERBB2)
05213 Endometrial cancer
102990192 (ERBB2)
05224 Breast cancer
102990192 (ERBB2)
05223 Non-small cell lung cancer
102990192 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102990192 (ERBB2)
01524 Platinum drug resistance
102990192 (ERBB2)
01522 Endocrine resistance
102990192 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcad01001
]
102990192 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pcad04147
]
102990192 (ERBB2)
04090 CD molecules [BR:
pcad04090
]
102990192 (ERBB2)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102990192 (ERBB2)
Protein kinases [BR:
pcad01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
102990192 (ERBB2)
Exosome [BR:
pcad04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
102990192 (ERBB2)
CD molecules [BR:
pcad04090
]
Proteins
102990192 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
CcmD
Motif
Other DBs
NCBI-GeneID:
102990192
NCBI-ProteinID:
XP_007112599
Ensembl:
ENSPCTG00005006950
UniProt:
A0A2Y9F099
LinkDB
All DBs
Position
Unknown
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRLLASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANASLSFLQEIQEVQGYVLIAHNRVSQVPLQRLRIVRGTQLFEDNYALAVLDNG
DLLESATPAARAAPGGLQDLQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LMLIDTNRSRACPPCSPACKAPHCWGESSKDCQSLTRTVCASGCARCKGPQPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFEGDGASNTAPLQPEQLRVFESLEEITGYLYISAWPDSLP
DLHVFQNLRVIRGRVLHDGAYSLTLQGLGIRWLGLRSLRELGSGLALIHRNARLCFVHTV
PWDQLFRNPHQALLHSANRPEVECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQRC
VEECRVLQGLPREYVKDRYCLPCHPECQPQNGSVTCFGSEADQCVACAHHKDPPFCVARC
PSGVKPDLSFMPIWKFPDEEGMCQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
ILLVVVVGLVFGTLIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPTSPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGSGGTAHRRHRSTSTRSGGGELTLGLEPSEEEPPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQNLPQHDCSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVRPQPPSPLEGPQPPPRPAGSTLERPKTLSPGKNGVVKDIFAFGAAVENPEYLAPR
GRAGPPSHPSPAFSPAFDNLYYWDQDSSERGSPPSTFEGTPTAENPEYLGLDMPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctgctggccagtcccgag
acccacctggacatgctccgccacctctaccagggctgtcaggtggttcagggtaacctg
gagctcacctacctgcccgctaacgccagcctctccttcctgcaggagatccaggaggtg
cagggctacgtgctcatcgctcacaaccgagtgagtcaggtccccctgcagaggctgcgg
atcgtgcgaggcacccagctgtttgaggacaactatgccctggccgtgctggacaatgga
gaccttctggaaagtgccacccctgctgcacgcgctgctccgggagggctgcaggacctg
cagctgcgaagcctcacagagatcctgaagggaggggtcttgatccagcggaaccctcag
ctctgccaccaggacacgattttgtggaaggacatcttccacaagaacaaccagctggcc
ctcatgttgatagacaccaaccgctcacgggcctgcccaccctgttctccagcttgtaaa
gctccccactgctggggagaaagttccaaggactgtcagagcttgacgcgaaccgtctgt
gccagcggctgtgcccgctgtaagggcccgcagcccaccgactgctgccacgagcaatgt
gctgccggctgcacgggccccaagcactctgactgtctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagctctggtcacctacaacacggacaccttcgag
tccatgcccaaccccgagggccgttataccttcggcgccagctgcgtgaccgcctgtcct
tacaactacctgtctacggacgtgggatcctgcaccctggtttgtcccctgaacaaccaa
gaggtgacagctgaggatggaacccagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctatggtctgggcatggaacacctgcgggaggtgagggcggtcaccagtgccaac
atccaggagtttgctggctgcaagaagatctttgggagcctggcgtttctgccggagagc
tttgagggggacggagcctccaacactgcccccctacagcctgagcagctcagagtattt
gagtctctggaggagatcacaggttacctgtacatctcagcgtggccagacagcctgccg
gacctccacgtcttccagaatctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcgctgaccctgcaagggctgggcatccgctggctggggctgcgctcgctgcgggaa
ctgggcagtgggctggccctcatccaccgcaacgcccgcctctgctttgtacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctccacagtgccaaccggcca
gaggtcgagtgcgtgggcgagggcctggcctgctacccgctgtgtgcccacgggcactgc
tggggtccagggcccacccagtgcgtcaactgcagccagttccttaggggccagcggtgc
gtggaagaatgccgagtactgcaggggctcccccgggagtacgtgaaggacaggtactgt
ctgccgtgccaccccgagtgtcagccccagaatggctcagtgacctgctttggctcggag
gccgaccagtgtgtggcttgcgcccaccacaaggatcctcccttctgcgtggctcgctgc
cccagcggtgtgaagcctgacctctccttcatgcccatctggaagttcccagatgaggag
ggcatgtgccagccatgccccatcaactgcacccactcctgtgtggacctggatgacaag
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgccgccgtggtgggc
atcctgctggtcgttgtcgtggggctggtcttcggcaccctcatcaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggagacagagctggtggagcccctg
acaccgagcggagcgatgccaaatcaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcaccgtctacaagggcatctggatc
cccgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatcc
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggctggtgtagggtcccca
tacgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcctagaccacgtccgggagcaccgcgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggacgtgcgg
ctcgtgcacagggacctggctgcccggaatgtgctggtcaagagtcccaaccatgtcaag
attacagactttgggctggctcggctgctggacattgacgagacagagtaccacgcggat
gggggcaaggtgcccatcaagtggatggcgttggagtccattctccgccggcggttcacc
caccagagtgatgtgtggagctatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctcctggagaagggggaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgtcggccgaggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaagacttgggccctaccagccccttg
gacagcaccttctaccgctcactgctggaggatgatgacatgggggacctggtggatgct
gaggagtacctggtaccccagcaaggcttcttctgcccagaccctgccccaggctctggg
ggcacagcccaccgcaggcaccgcagcacatccaccaggagtggcggtggtgagctgacg
ctgggtctggagccctcggaggaggagccccccaggtctccactggcaccttccgaaggg
gctggctctgatgtgtttgacggcgacttgggaatgggggcagccaaggggctgcagaac
ctcccccaacatgactgcagccctctacagcggtacagcgaggaccccacagtaccgctt
cctcccgagaccgatggctacgtcgcccccctgacatgcagcccccagcccgaatacgtg
aaccagccagaggttcggccacagcccccctcacccctagagggtcctcagcctccccct
cgacctgccggttccactctggaaaggcccaagactctctcccctgggaagaatggggtt
gtcaaagacatttttgcctttggggctgctgtggagaaccccgagtacttggcaccccgg
ggcagggctggccctccgtcccacccttctccggccttcagcccagcctttgacaacctc
tattactgggaccaggactcatcagagcggggctctccacccagcacctttgaagggacc
cctacagcagagaaccccgagtacctgggtctggacatgccagtatga
DBGET
integrated database retrieval system
