KEGG   Physeter macrocephalus (sperm whale): 102990550
Entry
102990550         CDS       T06011                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad01521  EGFR tyrosine kinase inhibitor resistance
pcad01522  Endocrine resistance
pcad04010  MAPK signaling pathway
pcad04014  Ras signaling pathway
pcad04015  Rap1 signaling pathway
pcad04066  HIF-1 signaling pathway
pcad04068  FoxO signaling pathway
pcad04081  Hormone signaling
pcad04114  Oocyte meiosis
pcad04115  p53 signaling pathway
pcad04150  mTOR signaling pathway
pcad04151  PI3K-Akt signaling pathway
pcad04152  AMPK signaling pathway
pcad04211  Longevity regulating pathway
pcad04213  Longevity regulating pathway - multiple species
pcad04510  Focal adhesion
pcad04550  Signaling pathways regulating pluripotency of stem cells
pcad04730  Long-term depression
pcad04750  Inflammatory mediator regulation of TRP channels
pcad04913  Ovarian steroidogenesis
pcad04914  Progesterone-mediated oocyte maturation
pcad04935  Growth hormone synthesis, secretion and action
pcad04960  Aldosterone-regulated sodium reabsorption
pcad05200  Pathways in cancer
pcad05202  Transcriptional misregulation in cancer
pcad05205  Proteoglycans in cancer
pcad05214  Glioma
pcad05215  Prostate cancer
pcad05218  Melanoma
pcad05224  Breast cancer
pcad05410  Hypertrophic cardiomyopathy
pcad05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102990550 (IGF1)
   04014 Ras signaling pathway
    102990550 (IGF1)
   04015 Rap1 signaling pathway
    102990550 (IGF1)
   04066 HIF-1 signaling pathway
    102990550 (IGF1)
   04068 FoxO signaling pathway
    102990550 (IGF1)
   04151 PI3K-Akt signaling pathway
    102990550 (IGF1)
   04152 AMPK signaling pathway
    102990550 (IGF1)
   04150 mTOR signaling pathway
    102990550 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    102990550 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102990550 (IGF1)
   04115 p53 signaling pathway
    102990550 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102990550 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    102990550 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    102990550 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    102990550 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    102990550 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102990550 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    102990550 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102990550 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    102990550 (IGF1)
   04213 Longevity regulating pathway - multiple species
    102990550 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102990550 (IGF1)
   05202 Transcriptional misregulation in cancer
    102990550 (IGF1)
   05205 Proteoglycans in cancer
    102990550 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    102990550 (IGF1)
   05218 Melanoma
    102990550 (IGF1)
   05215 Prostate cancer
    102990550 (IGF1)
   05224 Breast cancer
    102990550 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    102990550 (IGF1)
   05414 Dilated cardiomyopathy
    102990550 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102990550 (IGF1)
   01522 Endocrine resistance
    102990550 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:pcad04052]
    102990550 (IGF1)
Cytokines and neuropeptides [BR:pcad04052]
 Cytokines
  Growth factors (RTK binding)
   102990550 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 102990550
NCBI-ProteinID: XP_007130863
Ensembl: ENSPCTG00005016550
UniProt: A0A2Y9FWL7
LinkDB
Position
6:complement(35366157..35529353)
AA seq 210 aa
MGKISSLPTQLFKCCFCDFLKVKMHITSSSHLFYLALFLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKVSQPGVGMGVGHPCEICILSMWVSQTVTRSRSLLAHRSKKLHSHLR
GPSRTSLHIVNSPFHCSGPSDHQKMVEKSD
NT seq 633 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtaaagatgcacatcacgtcctcctcgcatctcttctacttggccctgttcttgctc
accttcaccagctctgccacggctggacctgagaccctctgtggggctgagttggtggac
gcccttcagttcgtgtgcggagacaggggcttttatttcaacaagcccacggggtatggc
tcgagcagtcggagggcgcctcagacaggaatcgtggacgaatgctgcttccggagctgt
gatctgaggaggctggagatgtactgcgcgcctctcaagcctgccaagtcggcccgctct
gtccgtgcccagcgccacaccgacatgcccaaggctcagaaggtaagccagcctggggtg
gggatgggggtcggccacccctgcgagatctgtatcctatccatgtgggtgagccaaaca
gtaactaggtcccgtagtctcctagctcacaggtcaaaaaagctccattctcacctgaga
ggtccatcccgtacatcactccacattgtaaactctcccttccactgctctggaccatct
gatcaccagaagatggtggagaagagtgattaa

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