Physeter macrocephalus (sperm whale): 102990689
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Entry
102990689 CDS
T06011
Symbol
NOTCH2
Name
(RefSeq) neurogenic locus notch homolog protein 2
KO
K20994
Notch 2
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad01522
Endocrine resistance
pcad04330
Notch signaling pathway
pcad04658
Th1 and Th2 cell differentiation
pcad04919
Thyroid hormone signaling pathway
pcad05165
Human papillomavirus infection
pcad05200
Pathways in cancer
pcad05206
MicroRNAs in cancer
pcad05207
Chemical carcinogenesis - receptor activation
pcad05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
102990689 (NOTCH2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
102990689 (NOTCH2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
102990689 (NOTCH2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102990689 (NOTCH2)
05206 MicroRNAs in cancer
102990689 (NOTCH2)
05207 Chemical carcinogenesis - receptor activation
102990689 (NOTCH2)
09162 Cancer: specific types
05224 Breast cancer
102990689 (NOTCH2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
102990689 (NOTCH2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
102990689 (NOTCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
EGF
hEGF
EGF_TEN
EGF_CA
EGF_2
Ank_2
Ank
NOD
Notch
NODP
Ank_5
Ank_3
Ank_4
EGF_3
EGF_Teneurin
JAG1-like_EGF2
Motif
Other DBs
NCBI-GeneID:
102990689
NCBI-ProteinID:
XP_023975560
Ensembl:
ENSPCTG00005016186
UniProt:
A0A2Y9SGX7
LinkDB
All DBs
Position
4:77897247..78092043
Genome browser
AA seq
2471 aa
AA seq
DB search
MPALRPAPLWALLALWLCRATPARALQCRDGYEPCVNEGICVTYHNGTGYCKCPEGFLGE
YCQHRDPCEKNRCQNGGTCVAQAMLGKATCQCAPGFTGEDCQYSTTHPCFVSHPCLNGGA
CHVLSRDTYECTCQVGFTGKLCQWTDTCLSQPCANGSTCTTVANQFSCTCLAGFTGQKCA
SDVNECDVPGQCQHGGTCLNLPGSYQCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTG
DFAFECNCLPGFEGVTCEWNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
ECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGGDCTEDVDECA
MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCKNDATCLDKIGGFTC
LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
GAICSDQIDECYSGPCLNEGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASSPCVHGVCM
DGVNRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCICPEGPHHPSCYSQ
VNECLSNPCVHGNCTGGLSGYKCLCDAGWVGINCEVDRNECLSNPCQNGGTCDNLVNGYR
CTCKKGFKGYNCLVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN
PCENAGVCKEAPNFESYTCLCSPGWQGQRCTVDIDECVSKPCMNHGLCHNTQGSYMCECP
PGFSGMDCEEDIDDCLANPCQNGGSCVDGVNTFSCLCLPGFTGDRCQTDMDECLSEPCKN
GGTCSDYVNSYTCKCQAGFDGVHCENNIDECTESSCFNSGTCIDGINSFSCLCPVGFTGP
FCLHEINECNSHPCLNEGVCVDGLGTYRCICPLGYTGKNCQTLVNLCSRSPCKNKGTCIQ
EKAQSRCLCPSGWAGAYCDVPNVSCEVAASHRGVTVDRLCQHSGICISAGNSHHCQCPLG
YTGSYCEDQLDECSSNPCQHGATCRDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCVDRIGGYSCRCLPGFAGER
CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA
VASNMPDGFICRCSPGFSGARCQSSCGQVKCRRGEQCVHTASGPRCFCPNPQDCNAGCAS
SPCQHGGSCYPQRQPPYYSCKCSPPFWGSHCEFYTAPTSTPPATCLSQYCADKARDGICD
EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTAECLFDNFECQRNS
KTCKYDKYCADHFKDNHCDQGCNSEACGWDGLDCAADRPENLAQGTLVIVVLMPPEQLLQ
DARSFLRALGTLLHTNLRIKRDAQGDLMVYPYYGEKSAAMKKQRLTRRSLPGDQEQEVAG
SQVFLEIDNRQCVQDSDQCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPKRTQLIY
LLAVAVVIVLFIILLGVIMAKRKRKHGSLWLPEGFTLRRDSSNHKRREPVGQDAVGLKNL
SVQVSEANLIGSGTSEHWVDDEGPQPKKARAEDEALLSEEDDPIDRRPWTQQHLEAADIR
RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDMSDEDEDAEDSSANIIT
DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
KKSRRPNAKSVVPCSLPNLAKEAKEAKGSRRKKSLSDKGQLSESSVTLSPVDSLESPHTY
VSDTTSSPMITSPGILQASPNPVLATAAPPAPVHAQHALSFSNLHEMQPLAHGANTVLPS
VSQLLSHHHIVPPGSGSAGSLGRLHPVTVPADWMNRVEVNETQYNEMFGMVLAPAEGTHP
GITPQSRPPEGKHLPAPREPLPPIVTFQLIPKGSIAQPAGAAQPPSSCPPAVAGTLPTMY
QIPEMARLPSMAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGSQRGPGAHMS
EPPRSNMQVYA
NT seq
7416 nt
NT seq
+upstream
nt +downstream
nt
atgcctgccctgcgccccgctccgctgtgggcgctgctggcactgtggctgtgccgcgcg
acccccgcgcgtgcattgcaatgtcgggacggctatgagccctgtgtaaatgaaggaata
tgtgttacctaccacaatggtacagggtactgcaaatgcccagagggattcttgggagaa
tattgtcaacatcgagacccctgtgagaagaaccgctgccagaatggtgggacgtgtgtg
gcccaggctatgttggggaaagccacatgccagtgtgccccgggcttcacaggcgaggac
tgccagtactcgaccactcacccctgctttgtgtctcacccttgcctgaatggaggcgcc
tgccatgtgctgagccgggatacctatgagtgcacctgccaagtcggttttacaggtaaa
ctgtgccaatggactgatacctgtctgtctcagccctgtgcaaatggaagtacctgtacc
actgtggccaaccagttctcctgcacatgcctcgcaggcttcacagggcagaagtgcgcg
agtgatgtcaatgagtgtgacgttccaggacaatgccagcacggtggcacctgcctcaac
ctcccgggttcctatcagtgccagtgcccccagggcttcacaggccagcactgtgacagt
ccctacgtgccctgtgcaccctccccctgtgtcaatggaggcacctgccggcagactggt
gacttcgcctttgagtgcaactgccttccaggttttgaaggggtcacctgtgagtggaat
attgatgactgtcctaatcacaagtgtcagaatggaggggtttgtgtggatggggtcaac
acttacaactgccgctgcccccctcagtggacaggacagttctgcacagaggatgtggat
gagtgcctgctgcaacccaatgcctgtcaaaacgggggcacctgtaccaaccgcaatggg
ggctatggctgtgtgtgcgttaatggctggagtggagatgactgcagtgagaacattgat
gactgcgccttcgcctcctgcactccaggctccacctgcattgatcgtgtggcctccttc
tcttgcatgtgcccagaaggaaaggcaggtctcttatgtcatctggatgatgcatgcatc
agcaacccctgccacaagggggcactgtgtgataccaaccctctgaatgggcagtatatt
tgcacctgtccacaaggctacaaagggggtgactgtacagaagacgtggatgagtgtgcc
atggccaatagcaatccttgtgagcatgcgggaaaatgtgtgaacacagatggtgccttc
cactgtgagtgtctgaagggctatgcagggcctcgttgcgagatggacatcaatgagtgc
cattcagacccctgcaagaatgatgccacctgtctggataagattggaggcttcacatgt
ctgtgcatgccaggtttcaaaggtgtgcattgtgaattggagataaatgaatgtcagagc
aacccttgcgtgaacaatgggcagtgtgtggataaagtcaatcgcttccagtgtctgtgt
ccgcctggtttcactgggccagtttgccagattgatattgatgactgttccagtactcca
tgtctgaatggggcaaagtgtatagatcacccaaatggttatgaatgccagtgcgccaca
ggattcactggtgtgttgtgtgaggagaacatcgacaactgtgaccctgatccttgccac
catggccagtgtcaggatgggattgattcctacacctgcatctgcaatccagggtacatg
ggcgccatctgcagcgaccagatagatgaatgttacagcggcccttgcttgaatgagggt
cgctgcatcgacctggtaaatggttaccagtgcaactgccagccaggcacatcaggtgtt
aattgtgaaatcaattttgatgactgtgcaagtagcccttgtgtccatggagtctgcatg
gatggcgttaatcgttatagctgcgtctgctcaccaggatttacagggcagagatgtaac
attgacattgatgagtgtgcctccaatccctgtcgtaagggtgcaacatgtatcaacgat
gtgaacggtttccgctgtatatgccctgagggaccccatcatcccagctgctactcacag
gtgaacgagtgcctgagcaatccctgtgtccatggaaactgtactgggggtctcagtgga
tacaagtgcctctgtgatgcaggctgggttggcatcaactgtgaagtggacagaaatgaa
tgtctttctaatccatgccagaacggaggaacttgtgacaatctggtgaatggatacagg
tgcacttgcaagaagggctttaaaggctataactgtctggtgaatattgatgaatgtgct
tcgaatccatgtctgaaccaaggaacctgctttgatgatataagtggttatacctgccac
tgtgtgctgccatacacaggcaagaactgtcagactgtattagctccctgttccccaaac
ccttgtgagaatgctggtgtttgcaaagaggcaccaaattttgagagttacacctgcctg
tgttctcctggctggcaaggtcaacgatgtacagttgacattgatgagtgtgtctccaag
ccctgcatgaaccacggtctctgccataacacccagggcagctacatgtgcgagtgtcct
ccaggcttcagtggtatggactgtgaagaggacatcgatgactgccttgccaatccttgc
cagaatggaggttcctgtgtagacggagtgaatactttctcctgcctatgccttccgggc
ttcactggggacaggtgtcagacagacatggatgagtgtctgagtgaaccctgtaagaat
ggagggacctgctctgactatgtcaacagttacacctgcaagtgccaggcgggatttgat
ggagtccactgtgagaacaacattgacgagtgcactgagagctcctgtttcaacagtggc
acatgtattgatgggattaactccttctcttgcttgtgccctgtgggcttcactggcccc
ttctgcctccatgagatcaatgaatgcaactctcatccatgcctgaatgaaggagtatgt
gttgatggcctgggtacctaccgctgcatctgcccattgggctacactgggaaaaactgt
cagaccctggtgaacctctgtagtcggtctccatgtaaaaacaaaggtacttgcattcag
gaaaaagcacagtcccggtgcctgtgtccatctggatgggctggtgcttactgtgacgtg
cccaatgtctcctgtgaggttgcagcctcccacagaggggtgaccgttgaccgcttgtgc
cagcactcaggcatctgtatcagtgctggcaactcacatcactgccagtgccccctgggc
tacaccgggagctactgtgaggatcagcttgatgagtgctcatccaacccctgccagcac
ggagccacctgcagggacttcattggtggatacagatgtgagtgtgtcccaggatatcag
ggtgtcaattgcgagtatgaagtggatgagtgccagaaccagccatgccagaatggaggc
acctgtatcgaccttgtgaaccatttcaagtgctcctgcccaccaggcactcggggcctg
ctttgtgaagagaacattgatgactgtgccaggggtccccactgccttaatggcggtcag
tgtgtggataggattgggggctacagttgtcgctgcttgcctggctttgctggagagcgg
tgtgagggggacatcaacgagtgcctctccaacccctgcagctctgagggcagcctagac
tgcatacagcttaccaatgactacctgtgtgtctgccgcagtgcctttactggtcgtcac
tgtgaaactttcgtcgatgtgtgtccccagatgccttgcctgaatggagggacttgtgct
gtggccagcaacatgcctgatggtttcatttgtcgttgttccccgggattctctggggcg
agatgccagagcagctgtggacaagtgaagtgtaggagaggggagcagtgtgtgcacaca
gcctcaggaccccgctgcttctgccccaacccccaggactgcaacgcaggctgtgccagt
agcccctgccagcacgggggcagctgctaccctcagcgccagcctccttattactcttgc
aagtgttctccgccgttctggggcagccactgtgaattctacacagctcccaccagcacc
cctcctgccacctgtctgagccagtattgtgccgacaaagctcgggatggcatctgcgat
gaggcctgcaacagccatgcctgccagtgggatgggggtgactgttccctcaccatggag
aacccctgggccaactgctcctccccgcttccctgctgggattacatcaacaaccagtgt
gatgagctgtgcaacacggctgagtgcctgtttgacaactttgaatgccagaggaatagc
aagacatgcaaatatgacaaatactgtgcagaccacttcaaagacaaccattgtgaccag
ggatgcaacagtgaggcgtgcggctgggacgggctggactgtgctgctgaccggccagaa
aacctggcacagggtaccctggtcattgtggtgctgatgccacctgaacaactgctccag
gatgctcgcagcttcttgcgggcgctgggcaccctgctccacaccaacctacgcatcaaa
cgggatgcccagggggacctcatggtctacccctattatggtgaaaagtcagctgccatg
aagaagcagagattgacgcgcaggtcccttcctggcgatcaagaacaggaagtggctggc
tctcaggtattcctggaaattgacaaccgccagtgtgttcaagattcagaccagtgcttc
aagaatacggatgcagcagcagctcttctggcatctcacgccatccaggggaccctgtcg
taccctcttgtgtctgttgtcagtgaatccctgaccccaaaacgcacccagcttatctat
ctacttgctgttgctgttgttattgtcttgtttattatcctgctgggggttatcatggca
aaacgaaagcgtaagcatggttccctctggctgcctgaaggcttcacccttcgccgtgac
tccagcaatcacaaacgtcgcgagccagtgggacaggatgccgtggggctgaaaaatctc
tcagtgcaagtctcagaggctaacctaattggttctggaacaagtgaacattgggtcgac
gatgaagggccccagccaaagaaagccagggctgaagatgaggctttactctcagaagaa
gatgatcccatcgatcgacggccatggacacagcagcaccttgaagctgcagatatccgt
aggacaccgtctttggctctcactcctccgcaggcagagcaggaagtggatgtgctggat
gttaacgtccgcggcccagatgggtgcaccccactgatgctggcttctctccgaggaggc
agctcagatatgagtgatgaagatgaagatgcagaggactcttccgccaacatcatcaca
gacttggtctaccagggtgccagcctccaagcccagacagaccggactggtgagatggcc
ctgcatcttgcagcccgctactcgagggccgatgctgccaagcgcctcctggatgcgggt
gcagatgccaatgcccaggacaacatgggccgctgccctctccatgctgcagtggcagct
gatgcccaaggtgtcttccagatactgatccgcaaccgagtaactgatctagatgccagg
atgaatgatggcaccacacccctgatcctggctgcccgcctagctgtggagggaatggtg
gcagagttgatcaactgccaagcagatgtgaatgcagtggatgaccacggaaaatctgct
cttcactgggcagctgctgtgaataatgtggaggcgacccttttgctgttgaaaaatggg
gccaaccgagacatgcaggacaacaaggaagagacccctctgtttcttgctgcccgggag
gggagctatgaagcagccaagatcctgttagaccattttgccaatcgggacatcacagac
cacatggatcgtcttccccgggacgtggctcgggaccgcatgcaccatgacattgtgcgc
ctgctggatgagtacaatgtgaccccgagccctccaggcaccgtgctgacttctgctctg
tcacctgtcatctgtggacccaacagatcttttctcagtctgaagcacaccccgatgggc
aagaagtctagacggcccaatgccaagagtgttgtgccctgtagcctccctaaccttgcc
aaggaggccaaggaggccaaggggagtaggaggaagaagtctctgagtgacaagggccag
ttgtctgagagctcagtgactctgtcccccgtcgattccctagaatctcctcacacatat
gtttctgataccacatcctctccgatgattacatcccccgggatcttacaggcctcaccc
aaccctgtgttggccactgctgccccccctgccccagtccatgcacagcatgcactgtct
ttctctaaccttcatgagatgcagcccttggctcacggggccaacactgtgcttccctca
gtgagccagctgctgtcacaccaccacattgttcccccaggcagtggcagtgcggggagc
ttgggtaggctacatccagtcactgtcccagcggactggatgaaccgtgtggaggtgaat
gagacccagtacaacgagatgtttggtatggtcctggctccagctgagggcactcaccct
ggcataactccccagagcaggccgcctgaagggaagcatttacctgcccctcgagagccc
ttgccccccatcgtgactttccagctaatccccaaaggcagcattgcccaaccagccggg
gctgcccagcctccgtccagctgccctccagctgttgcaggcaccctgcccaccatgtat
cagattccagaaatggctcgtttgcccagtatggcttttcccactgccatgatgccccag
caggatgggcaggttgctcagaccattctcccagcctaccatccctttccagcctctgtg
ggcaagtatcccacacccccttcacagcatagctatgcttcctccaatgctgctgagaga
acgcccagtcacagtggtcacctccagggtgagcatccctacctgacaccatcccccgag
tctcctgaccagtggtcaagttcatccccccactctgcttctgactggtcagatgtgacc
accagccccactcctgggggtgctggaggaagtcagcggggacctggggcacacatgtct
gagccaccacgcagcaacatgcaggtctatgcatga
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integrated database retrieval system
