Physeter macrocephalus (sperm whale): 102991639
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Entry
102991639 CDS
T06011
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad01521
EGFR tyrosine kinase inhibitor resistance
pcad01522
Endocrine resistance
pcad04010
MAPK signaling pathway
pcad04012
ErbB signaling pathway
pcad04014
Ras signaling pathway
pcad04062
Chemokine signaling pathway
pcad04068
FoxO signaling pathway
pcad04072
Phospholipase D signaling pathway
pcad04150
mTOR signaling pathway
pcad04151
PI3K-Akt signaling pathway
pcad04510
Focal adhesion
pcad04540
Gap junction
pcad04630
JAK-STAT signaling pathway
pcad04650
Natural killer cell mediated cytotoxicity
pcad04660
T cell receptor signaling pathway
pcad04662
B cell receptor signaling pathway
pcad04664
Fc epsilon RI signaling pathway
pcad04714
Thermogenesis
pcad04722
Neurotrophin signaling pathway
pcad04810
Regulation of actin cytoskeleton
pcad04910
Insulin signaling pathway
pcad04912
GnRH signaling pathway
pcad04915
Estrogen signaling pathway
pcad04917
Prolactin signaling pathway
pcad04926
Relaxin signaling pathway
pcad04935
Growth hormone synthesis, secretion and action
pcad05034
Alcoholism
pcad05160
Hepatitis C
pcad05161
Hepatitis B
pcad05163
Human cytomegalovirus infection
pcad05165
Human papillomavirus infection
pcad05200
Pathways in cancer
pcad05205
Proteoglycans in cancer
pcad05206
MicroRNAs in cancer
pcad05207
Chemical carcinogenesis - receptor activation
pcad05208
Chemical carcinogenesis - reactive oxygen species
pcad05210
Colorectal cancer
pcad05211
Renal cell carcinoma
pcad05213
Endometrial cancer
pcad05214
Glioma
pcad05215
Prostate cancer
pcad05220
Chronic myeloid leukemia
pcad05221
Acute myeloid leukemia
pcad05223
Non-small cell lung cancer
pcad05224
Breast cancer
pcad05225
Hepatocellular carcinoma
pcad05226
Gastric cancer
pcad05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102991639 (SOS1)
04012 ErbB signaling pathway
102991639 (SOS1)
04014 Ras signaling pathway
102991639 (SOS1)
04630 JAK-STAT signaling pathway
102991639 (SOS1)
04068 FoxO signaling pathway
102991639 (SOS1)
04072 Phospholipase D signaling pathway
102991639 (SOS1)
04151 PI3K-Akt signaling pathway
102991639 (SOS1)
04150 mTOR signaling pathway
102991639 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102991639 (SOS1)
04540 Gap junction
102991639 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102991639 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
102991639 (SOS1)
04660 T cell receptor signaling pathway
102991639 (SOS1)
04662 B cell receptor signaling pathway
102991639 (SOS1)
04664 Fc epsilon RI signaling pathway
102991639 (SOS1)
04062 Chemokine signaling pathway
102991639 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
102991639 (SOS1)
04912 GnRH signaling pathway
102991639 (SOS1)
04915 Estrogen signaling pathway
102991639 (SOS1)
04917 Prolactin signaling pathway
102991639 (SOS1)
04926 Relaxin signaling pathway
102991639 (SOS1)
04935 Growth hormone synthesis, secretion and action
102991639 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
102991639 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
102991639 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102991639 (SOS1)
05206 MicroRNAs in cancer
102991639 (SOS1)
05205 Proteoglycans in cancer
102991639 (SOS1)
05207 Chemical carcinogenesis - receptor activation
102991639 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
102991639 (SOS1)
05231 Choline metabolism in cancer
102991639 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
102991639 (SOS1)
05225 Hepatocellular carcinoma
102991639 (SOS1)
05226 Gastric cancer
102991639 (SOS1)
05214 Glioma
102991639 (SOS1)
05221 Acute myeloid leukemia
102991639 (SOS1)
05220 Chronic myeloid leukemia
102991639 (SOS1)
05211 Renal cell carcinoma
102991639 (SOS1)
05215 Prostate cancer
102991639 (SOS1)
05213 Endometrial cancer
102991639 (SOS1)
05224 Breast cancer
102991639 (SOS1)
05223 Non-small cell lung cancer
102991639 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
102991639 (SOS1)
05160 Hepatitis C
102991639 (SOS1)
05163 Human cytomegalovirus infection
102991639 (SOS1)
05165 Human papillomavirus infection
102991639 (SOS1)
09165 Substance dependence
05034 Alcoholism
102991639 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102991639 (SOS1)
01522 Endocrine resistance
102991639 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_19
PH_10
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
102991639
NCBI-ProteinID:
XP_023974332
Ensembl:
ENSPCTG00005006966
UniProt:
A0A2Y9SAH3
LinkDB
All DBs
Position
12:complement(56031889..56185456)
Genome browser
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENVQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTIFIQVTLPHGPRSASVSSISL
TKSTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSVSD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHSNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPIPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcatcctactcttgagtct
agtgatgatgctcttcagtatgttgaagaattaattttgcagttattaaatatgctatgc
caagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccagtcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttgttaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagac
attttaaagctggtggggaattatgtgcgaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacaatacataagggaacttaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtggatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtagaaatgacagatgaaggcagtccccatccattagtagga
agttgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacgacctggttttcatgatcgtttccttagtcagttatcaaagcctggagcg
gcactctatttgcagtcaataggcgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttctgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatctgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaggatgacaccaatgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagcgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttaatatctttacagtaccggagtacactggaaaggatgcttgatgtgacaatgctacag
gaagaaaaggaggagcagatgaggctccctagtgctgatgtttatagatttgcagagcct
gactctgaagaaaatatcatatttgaagaaaacgtgcagcccaaagctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggctcacataccatatgtacgcagat
cccaattttgttcggacatttcttacaacatatagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccttgagtgcagaactaaaaaggtttagaaaagaa
tatatacagcctgtacaactgcgagtattaaatgtatgtcggcactgggtagagcaccac
ttctacgattttgaaagagatgcagatcttttgcagcgaatggaggaatttattggaaca
gtaagaggtaaagcaatgaaaaagtgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcgcctcccaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaggaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcataccactaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgagattctgcaa
gtctttcaagagctgaacaacttcaatggtgtccttgaggttgtcagtgctatgaactca
tcacctgtatacagactagaccacacgtttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaactaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaaggcatgggaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggcgagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccaatgggaaatagt
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtactatgagacatcccacacctctgcagcaagagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttctagtaccacagat
gtttgcagcgtatttgattctgatcattcaagcccttttcactcaagcagcgataccatc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaagagcactgatgaagtgcctgtcccccctcctgttcctccacgaagacgaccagaa
tctgccccagcggaatcttcgccatctaagatcatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcctattcaccacgatattcagtatcagac
cggacctctatatcagatcctcctgaaagccctcccttattacctccacgagaacctgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatagtaatgccttcttcccaaacagcccttccccctttacaccacctcct
cctcaaacaccttctcctcatggcacaagaaggcatctgccatcaccaccactgacacaa
gaagtggaccttcattccattgctgggccgcctattcctccacgacaaagcacttctcaa
catatccctaaactccctccaaaaacttacaaaagggagcatacacacccatccatgcac
agagatggaccaccactgttggagaatgcccattcttcctga
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integrated database retrieval system
