Physeter macrocephalus (sperm whale): 102991676
Help
Entry
102991676 CDS
T06011
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00230
Purine metabolism
pcad01100
Metabolic pathways
pcad04927
Cortisol synthesis and secretion
pcad04934
Cushing syndrome
pcad05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
102991676 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
102991676 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
102991676 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
102991676 (PDE8A)
Enzymes [BR:
pcad01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
102991676 (PDE8A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS
PAS_9
PAS_4
PAS_3
Response_reg
PAS_8
DUF5894
Band_7_C
Motif
Other DBs
NCBI-GeneID:
102991676
NCBI-ProteinID:
XP_023973182
Ensembl:
ENSPCTG00005022193
UniProt:
A0A2Y9S790
LinkDB
All DBs
Position
11:complement(42166038..42291205)
Genome browser
AA seq
757 aa
AA seq
DB search
MRFHPDQLQVLLVFPKEDKQCNGFCRACEKAGFKCTVIKEAQTALACYLDKHHDIIIIDH
RNPQQLDGEVLCRSLRSSELSENTVIVGVVRRAVREESSVMSLIEAGFTRRYLENPSAMA
CYNELLQMEFGLVHPQLKLRACNSMFTALEKSQEAIEITSEDHIVQYANPAFETTMGYES
GELIGKDLAEVPVNEKKADLLDTINSCIRIGKEWQGICSAKEKNGDNVQQNVKILPVIGQ
GGKIRHYVSIVRACNGNNKATKIAECVQSDTHTDNQSGKHNDRRKSSLDVRTAASRTSKV
SSQRRRSSMARIHSMKIEAPITKAINIISAAQESSPMPVTEALDRVLEILRTTELYSPQF
DAKDDDPHAIDLVGGLMSDVFRRPSRNEYVLSTKNLQQVSSSVITPTSLHDVPSQITQAM
ENEDSWDFDIFELEAATHKRPLIYLGLKIFARFGVCEVLKCSETTLRSWLQIIEANYHAS
NPYHNSTHSADVLHATAYFLCKERIKQTLDPLDEVTALIAATVHDLDHPGRTNSFLCNAG
SKLAILYNDTAVLERHHAALAFQLTTGDDKCNIFKNMERNDYRMVRQSIIDMVLATEMTK
HFEHVNKFVNSINKPLAALEEDGETDKNQEAIITMLRTPDNHSLIKRMLIKCADVSNPCR
PLEQCIEWAARISEEYFSQTDEEKRQDLPVVMPVFDRNTCSIPKSQISFIDYFITDMFAA
WDAFVDLPELMQHLDNNFKYWKGLDKMKLRSLRPPPE
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgagatttcatccagatcagctccaggtacttttagtgtttcccaaagaagataagcag
tgtaatggattctgtagggcatgtgaaaaagcagggtttaagtgtacagttatcaaggag
gctcagacggcccttgcctgttacctggacaaacatcatgacatcatcatcattgaccac
agaaatccccaacagctggacggggaggtgctgtgcaggtctctcagatcatcagaactc
tcagaaaacacagttattgttggtgtagtacgcagggcggttagagaagagtcatctgta
atgtctctcattgaggctggctttacaaggaggtatttagaaaaccccagcgccatggcc
tgttacaatgaactgctccagatggagtttggattggtgcacccacagctgaaactcagg
gcttgtaactctatgttcactgcattagagaaaagtcaagaagcaattgaaattacaagt
gaagaccacattgtacagtatgcaaatccagcatttgaaacaacaatgggctatgagtca
ggtgaattaatagggaaggatttagcagaagtgcctgtaaatgaaaaaaaggctgatttg
ctcgatactataaattcatgcatcaggataggcaaggaatggcaaggaatttgctctgcc
aaagagaaaaacggagataatgtacaacaaaatgtgaagatactacctgtcattggacag
ggaggaaaaattagacactatgtgtccattgtcagagcatgcaatggcaacaataaggct
acgaaaatagctgaatgtgttcagtctgatactcatacagataatcagtcaggcaaacat
aacgacaggagaaaaagctcactagatgtcagaactgctgcctctcgaacaagcaaagtt
tccagccagagacgacgctcctccatggcccggatacattccatgaagatcgaggcgccc
atcaccaaggcaatcaatattatcagtgctgcccaggaaagcagtcccatgcctgtgaca
gaagccttagatcgtgtgctggaaattctaagaaccactgaattatattcaccacaattc
gatgctaaggacgatgatcctcatgccattgaccttgttgggggcttaatgtctgatgtt
tttcgaagaccatccaggaatgagtatgttctttcaacaaaaaaccttcaacaggtttcc
agcagtgtaatcacccccacctcccttcacgacgtcccatcacagataactcaggccatg
gaaaatgaggactcctgggactttgatatttttgaactggaggctgccactcataaaagg
cctttgatttatcttggtctcaaaatatttgctcgctttggagtctgtgaagtcttaaaa
tgctctgagacaacgctgagatcgtggttgcaaattatcgaagccaattatcatgcttct
aacccctaccacaattctacacattctgccgatgtacttcacgccactgcctattttctc
tgcaaagagaggataaagcaaactttagatccacttgatgaggtcactgccctcattgca
gccactgtccatgacctggaccaccccgggagaaccaactccttcctgtgcaatgctggg
agcaagctggccattctgtataacgacactgctgtgctcgagagacaccatgcggccttg
gccttccagctgaccactggtgatgataaatgcaacatctttaaaaacatggagaggaat
gactaccggatggtgcgccagagtattatcgacatggtcttagccacagaaatgacaaag
cactttgagcacgtcaacaaatttgtcaacagcatcaacaagcccttggcagcattagag
gaagatggggaaactgataaaaatcaagaagccataatcactatgctcagaactccagac
aaccacagtttgatcaaacgaatgctgattaagtgtgctgatgtatccaatccctgccga
cccctggagcagtgcattgagtgggctgcacgtatctcagaagaatatttttctcagact
gatgaagagaagcgacaggacttgcctgtggtgatgccagtttttgacagaaatacctgc
agcatccccaaatcccaaatctctttcattgactacttcatcacagacatgtttgctgct
tgggatgcctttgtagacctgcctgagttaatgcagcatcttgacaacaattttaaatac
tggaagggactggacaaaatgaagctgcggagcctccgcccacctcctgaatag
DBGET
integrated database retrieval system
