Physeter macrocephalus (sperm whale): 102991967 Help Entry 102991967         CDS       T06011                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism pcad  Physeter macrocephalus (sperm whale) Pathway pcad00220   Arginine biosynthesis pcad00330   Arginine and proline metabolism pcad01100   Metabolic pathways pcad04020   Calcium signaling pathway pcad04081   Hormone signaling pcad04145   Phagosome pcad04371   Apelin signaling pathway pcad04713   Circadian entrainment pcad04730   Long-term depression pcad04926   Relaxin signaling pathway pcad04970   Salivary secretion pcad05010   Alzheimer disease pcad05014   Amyotrophic lateral sclerosis pcad05022   Pathways of neurodegeneration - multiple diseases pcad05410   Hypertrophic cardiomyopathy pcad05412   Arrhythmogenic right ventricular cardiomyopathy pcad05414   Dilated cardiomyopathy pcad05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:pcad00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     102991967 (NOS1)    00330 Arginine and proline metabolism     102991967 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     102991967 (NOS1)    04020 Calcium signaling pathway     102991967 (NOS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     102991967 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     102991967 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     102991967 (NOS1)   09154 Digestive system    04970 Salivary secretion     102991967 (NOS1)   09156 Nervous system    04730 Long-term depression     102991967 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     102991967 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102991967 (NOS1)    05014 Amyotrophic lateral sclerosis     102991967 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     102991967 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     102991967 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     102991967 (NOS1)    05414 Dilated cardiomyopathy     102991967 (NOS1)    05416 Viral myocarditis     102991967 (NOS1) Enzymes [BR:pcad01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      102991967 (NOS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase Flavodoxin_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  102991967 NCBI-ProteinID:  XP_028335872 Ensembl:  ENSPCTG00005016440 UniProt:  A0A455AHQ6 LinkDB All DBs Position 19:complement(14612729..14769401) Genome browser AA seq 1076 aa AA seqDB search MENHTFSVKQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTRPLGPPTSAVDLSHQPSASKEQTLAVDGATGPGNGPQHVPDQGQEAGLLSHTNGLAP RPPSQDPAKKSSGENSQLLREIEPVLNLLTSGSKGISGGGPARAETKDAEIQVDRDLDGK SHRPLPLGVENDRVFNDLWGKGNMPVVLNNPYSEKEQPPASGKQSPIKNGSPSKCPRFLK VKNWETDVVLSDTLHLKSTLGMGCTEHICMGSIMLPSQQIRRPEDVRTKEQLFHLAKEFI DQYYSSIKRFGSKAHLERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRCVGRIQWS KLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRY AGYKQPDGSILGDPASVEFTQICLQQGWKPPRSRFDILPLLLQANGNDPELFQIPPELVL EVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDSS RYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHM ENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNSHVWKGTNGT PTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFD AKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVHEERKYRE PLRLFPRKGPPLPRDDTGVHRLAAARDSQRRSYKVRFNSVSSYSDSRKSSGNGPDLRDNF ESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMKEGDELCGQEEAFR TWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYMAEAPELTQGLSNVH KKRVSAARLLSRQNLQSPKSRPKLSCLSQETIARYHESHTHHSHPQQETLNCKQST NT seq 3231 nt NT seq  +upstreamnt  +downstreamnt atggagaatcacacgttcagcgtcaagcagatccaacccaatgtcatttctgtccgcctc ttcaagcgcaaagtggggggcctggggttcctggtgaaggagagggtgagcaagccacct gtgatcatctccgacctgattcgagggggcgccgcggagcagagcggcctcatccaggct ggggacatcattctcgccgtcaacggccagcccttggtggacctgagctatgacagcgcc ctggaggtgctcagaggcattgcctccgagacccacgtggtcctcattctgaggggcccc gagggcttcaccacgcacctggagaccactttcactggggacgggacccccaagaccatc cgggtgacacggcccctgggtccgccaacctcagccgtcgatctgtcccaccagccatca gccagcaaagagcagaccctggcagtggacggggccacgggtcctggcaatgggccgcag cacgtgccagaccaggggcaggaggctggcttgctctcccacaccaatggcctggctccc aggcccccgagccaggaccctgccaagaagagttctggggagaacagtcaactgctcaga gagatagagcctgtgctgaatcttctcaccagcgggagcaaagggatcagcggaggggga cctgccagagcggagacaaaggacgcagaaatccaggtggacagagatctggacggcaaa tcacacagaccgctgcccctcggtgtggagaacgaccgcgtcttcaatgacctatggggg aagggcaacatgccagtcgtcctcaacaacccgtattcagagaaggagcagccccctgcc tcgggaaaacagtctcccataaagaatggcagcccctccaagtgccctcgcttcctcaag gtcaagaactgggagaccgatgtggttctctctgacaccctccaccttaagagcaccttg ggaatgggatgcaccgagcacatctgtatggggtccatcatgcttccttctcagcaaata cgaaggcctgaagacgtccgcacaaaagaacagctcttccatcttgccaaagagtttatt gatcagtactattcatcaattaaaagattcggctccaaagcccatctggagaggctggaa gaggtgaacaaagagattgaaaccaccagcacctaccagctcaaggacacagagctcatc tacggggccaagcacgcctggagaaatgcctcccgctgcgtcggccggatccagtggtcc aagctgcaggtgttcgatgcccgcgactgtaccacggctcacgggatgttcaactacatc tgtaaccatatcaagtatgccaccaacaaagggaacctcagatctgccatcaccatattt ccccagaggaccgacggcaagcatgactttcgagtctggaactcccagctcatccgctat gctggctacaagcagcctgacggctccatcctgggggatccagccagcgtggagttcaca cagatctgcctccagcagggctggaaacccccaagaagccgcttcgacatcctgccactc ctgctccaggccaacggcaatgaccctgagctcttccagattcctccagagctggtgctg gaagtgcccatcaggcaccccaagtttgaatggttcaaggaccttgggctgaagtggtac ggcctccccgctgtgtcaaacatgctcctggagatcggtggcctggagttcagcgcctgt cccttcagcggctggtacatgggcacagagattggcgtccgcgactactgtgacagctcc cgatacaacatcctggaggaagtggccaagaagatgaacttggacatgaggaagacatcc tccctgtggaaggaccaggcactggtggagatcaacattgcggtgctctacagcttccag agtgacaaagtgaccatcgttgaccaccactctgccaccgagtccttcattaagcacatg gagaatgaataccgctgccggggaggctgccccgctgactgggtgtggattgtgcccccc atgtctggcagcatcacccccgtcttccaccaagagatgctcaactaccgactcaccccc tccttcgaataccagcctgacccttggaacagccacgtctggaaaggtaccaacgggacc cccacaaagcggcgagccattggcttcaagaagctggcagaagccgtcaagttctcagcc aagctaatgggacaggccatggccaagagggtcaaggctaccatcctgtacgccacagag acgggcaaatcgcaggcttatgccaaaaccctgtgtgagatcttcaaacatgcctttgac gccaaggtgatgtccatggaagaatatgacattgtacacctggaacatgaaactctggtc ctggtggttaccagcaccttcggaaacggagacccccctgagaatggggagaaatttggc tgcgctttgatggaaatgaggcaccccaactctgtgcacgaggaaaggaagtaccgggaa cccttgcgtttatttccccgtaaagggcctcccctcccccgagatgacacaggagtccac cgtctggctgcagcccgtgacagccagcgcaggagctacaaggttcgtttcaacagtgtt tcctcctattccgactcccgcaaatcatcgggcaatgggccggacctcagagacaacttt gagagcacgggacccctggcgaatgtgaggttctccgtgttcggccttggctcgcgggcg taccctcacttctgcgcctttggacacgccgtggacaccctcctggaagagctgggtggg gagaggatcctgaagatgaaggagggggatgagctctgtgggcaggaagaggctttcagg acctgggccaagaaggtcttcaaggcagcctgtgatgtgttctgcgtgggagatgacgtc aacattgagaaggcaaacaactccctcatcagcaatgaccgcagttggaagaggaacaag ttccgcctcacctacatggccgaagctccagaactcacacaaggtctatccaatgtccac aaaaagcgggtctcagccgctcgactcctcagccgtcagaaccttcaaagtcctaaatcc aggccaaagttgagctgtttgagccaggagaccatagcaagatatcatgaatcacacacc caccactcccacccccaacaagagacccttaattgcaagcaaagtacttaa

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