Physeter macrocephalus (sperm whale): 102992566
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Entry
102992566 CDS
T06011
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad00520
Amino sugar and nucleotide sugar metabolism
pcad00541
Biosynthesis of various nucleotide sugars
pcad01100
Metabolic pathways
pcad01250
Biosynthesis of nucleotide sugars
Module
pcad_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
102992566 (GNE)
00541 Biosynthesis of various nucleotide sugars
102992566 (GNE)
Enzymes [BR:
pcad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
102992566 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
102992566 (GNE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
FGGY_N
DRTGG
zf-CCCH_Mcm10
Peptidase_M9
Glucokinase
Motif
Other DBs
NCBI-GeneID:
102992566
NCBI-ProteinID:
XP_023981988
Ensembl:
ENSPCTG00005018390
UniProt:
A0A2Y9SUX7
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Position
9:28522003..28561864
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AA seq
807 aa
AA seq
DB search
MTGRRKKLHLGSKAKTTASCCARLPNFRAAGRRAPPGRNTGRPPGAVPRPRKAPPRPGLL
AQPIAEFLPAHELYFKNLSKRKKQVMEKKENNRKLRVCVATCNRADYSKLAPIMFGIKME
PEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKL
PDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAH
YHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYI
VALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPN
FRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVR
DADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKDN
ISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVE
AAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVD
NDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHIVVSLD
GPDCSCGSHGCIEAYASGMALQREAKKLHDEDQLLVEGMSVPKDEAVGALHLIQAAKLGN
AKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHTVKDVIRQQALSSVQDVD
VVVSDLVEPALLGAASMVLDYTTRRIY
NT seq
2424 nt
NT seq
+upstream
nt +downstream
nt
atgactggaaggcgtaagaaattgcatctcgggtccaaggccaaaacgactgcctcgtgc
tgtgctcggcttccgaactttcgcgcggcaggcagacgagcccctccggggcggaacact
ggccggccgcccggggctgtgccacgaccacggaaggcgccaccccgccccggcctcctc
gcacagccaatcgcagaattcctccccgctcacgaactctattttaagaacctctcaaaa
agaaaaaaacaagtcatggagaagaaggagaataaccgaaagcttcgggtttgtgttgct
acttgcaaccgtgctgattattctaaactcgccccaatcatgtttggcattaaaatggaa
cctgagttctttgaacttgacgtggtggtacttggctctcacctgatagatgactatgga
aacacatatcgcatgattgaacaagatgactttgacattaacaccagactacacacaatt
gtcagaggggaagatgaggcagccatggtggagtcagtgggcctggcccttgtgaagcta
ccagatgttcttaaccgcctgaagcctgatatcatgattgttcatggagacaggtttgat
gccctggctctggctacgtctgctgccttgatgaacatccgaatccttcacattgaaggg
ggggaagtcagtgggaccattgacgactctatcagacacgctataacgaaactggctcat
tatcatgtgtgctgtacccgaagtgcagagcaacacctgatatccatgtgtgaggaccac
gatcgcatcttgttggcaggctgcccttcctatgacaaacttctctccgccaagaacaaa
gactacatgagcatcattcggatgtggttaggtgatgatgtaaaatctaaagattacatt
gttgcactacagcaccctgtgaccacggacattaagcattccataaaaatgtttgaatta
acattggatgcacttatctcatttaacaagcggaccctagttctgtttccaaatattgat
gcagggagcaaagagatggttcgagtgatgcggaagaagggcattgagcatcatcccaat
tttcgtgcagttaaacatgtcccatttgaccagtttatacagctggttgcccatgctggt
tgtatgattgggaacagcagctgtggggtacgagaggttggagcttttggaacacctgtg
atcaacctaggaacacgtcagattggaagagaaacaggggagaatgtccttcacgtccgg
gatgctgatacccaagacaaaatattgcaagcgctgcaccttcagtttggtaaacagtac
ccttgttcaaagatatatggggatggaaatgctgttccgaggattttgaagtttctcaaa
tctattgatcttcaagagccactacaaaagaaattctgttttcctcctgtgaaggataac
atctcccaagatattgaccatattcttgaaactctaagtgccttggctgttgatcttggt
gggacgaacctccgagttgcaatagtcagcatgaagggtgaaatagttaagaagtatact
cagttcaatcctaaaacctatgaagagaggattaatttaatcctacagatgtgtgtagaa
gctgcagcagaagctgtaaaactgaactgcagaattttgggagtaggcatttccacaggt
ggccgtgtaaatcctcgggaaggaattgtgctgcattcaaccaaactgattcaagagtgg
aactctgtggatctcaggacccccctgtctgacactttgcatctccccgtgtgggtagac
aatgatggcaactgtgctgccctggcagaaaggaaatttggccaaggaaagggccttgaa
aactttgtgacacttatcacaggcacaggaattggcggggggatcatccatcagcatgaa
ctgatccatggcagctccttctgcgctgcggagctcggccacattgtggtgtccctggat
gggcctgactgctcctgtggaagccatgggtgtattgaagcatatgcctctggaatggcc
ttgcagagggaagcaaaaaagctacatgatgaagaccagctcttggtggaagggatgtcc
gtgccaaaagacgaagctgtgggcgcactccatctcatccaagctgcgaaacttggcaat
gcaaaggcccagagcatcttgagaacagctggaacagcgttgggtcttggggttgtgaac
atcctccacactatgaatccttcccttgtgatcctctctggagtcctagccagtcactat
atccacactgtcaaagacgtcatccgccagcaagccttgtcctcggttcaggacgtggac
gtggtggtttcggatttggtggaacccgccctgctcggcgccgccagcatggttctggac
tacacgactcgcaggatctactag
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