KEGG   Physeter macrocephalus (sperm whale): 102993364
Entry
102993364         CDS       T06011                                 
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X3
  KO
K11411  NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad00760  Nicotinate and nicotinamide metabolism
pcad01100  Metabolic pathways
pcad04068  FoxO signaling pathway
pcad04148  Efferocytosis
pcad04152  AMPK signaling pathway
pcad04211  Longevity regulating pathway
pcad04213  Longevity regulating pathway - multiple species
pcad04218  Cellular senescence
pcad04310  Wnt signaling pathway
pcad04922  Glucagon signaling pathway
pcad04936  Alcoholic liver disease
pcad05031  Amphetamine addiction
pcad05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    102993364 (SIRT1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    102993364 (SIRT1)
   04068 FoxO signaling pathway
    102993364 (SIRT1)
   04152 AMPK signaling pathway
    102993364 (SIRT1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102993364 (SIRT1)
  09143 Cell growth and death
   04218 Cellular senescence
    102993364 (SIRT1)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    102993364 (SIRT1)
  09149 Aging
   04211 Longevity regulating pathway
    102993364 (SIRT1)
   04213 Longevity regulating pathway - multiple species
    102993364 (SIRT1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    102993364 (SIRT1)
  09165 Substance dependence
   05031 Amphetamine addiction
    102993364 (SIRT1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102993364 (SIRT1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:pcad03036]
    102993364 (SIRT1)
   03029 Mitochondrial biogenesis [BR:pcad03029]
    102993364 (SIRT1)
Enzymes [BR:pcad01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.286  protein acetyllysine N-acetyltransferase
     102993364 (SIRT1)
Chromosome and associated proteins [BR:pcad03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    SIRTs (sirtuins, class III HDACs)
     102993364 (SIRT1)
Mitochondrial biogenesis [BR:pcad03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    102993364 (SIRT1)
SSDB
Motif
Pfam: SIR2
Other DBs
NCBI-GeneID: 102993364
NCBI-ProteinID: XP_007121139
Ensembl: ENSPCTG00005004488
UniProt: A0A2Y9FEL5
LinkDB
Position
20:20333980..20368209
AA seq 446 aa
MCLCSGRKTILEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCH
GSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFH
RAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCD
VIINELCHRLGGEYTKLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLNISEGSSSPEG
TSPADSSVIVTLLDQETKSNGDDPDVSESKNCVEEQSQEVQTSARSPESANEQLESPDLK
NVASNTGEKNERTSVAETVRKCWPARLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDS
EDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDDTDVNESAGGTGFGADG
GEQEAVNEATSMKQEATSINYPSNIM
NT seq 1341 nt   +upstreamnt  +downstreamnt
atgtgcctgtgcagtggaaggaaaacaattttggaaatatatcctggacaattccaacca
tctctttgtcacaaattcatagccttgtcggataaggaaggaaaactacttcgcaactat
actcagaacatagatacactggaacaggttgcaggaatccaaaggataattcagtgtcat
ggttcctttgcaacagcatcttgcctgatttgtaaatataaagttgactgtgaagctgta
cgaggagatatttttaatcaggtggttcctcgatgtcctaggtgcccagctgatgaacca
cttgctatcatgaaaccagagattgtcttttttggtgaaaatttaccagaacagtttcat
agagccatgaagtatgacaaagatgaagttgatcttctcattgttattgggtcttccctg
aaagtaagaccagtagcactaattccgagttccataccccatgaagtgcctcagatatta
attaatagggaacctttgcctcacctgcattttgatgtagagcttcttggagactgtgat
gtcattattaatgaattgtgtcacaggttaggtggtgaatacaccaaactttgctgcaac
cctgtaaagctttcagaaattactgaaaaacctccacgaacacaaaaagaattggctcat
ttgtcagagttgccacccacacccctcaatatttcagaaggctcgagttcaccagaagga
acctcaccagcagattcttcagtgattgtcactcttttagaccaagaaacaaagagtaat
ggtgatgatccagatgtgtctgaatcaaaaaactgtgtcgaagaacaatcacaggaagtg
cagacttctgctaggagccctgaaagtgctaatgaacagttggagagtccggatttgaag
aatgttgcctccaatactggggagaaaaatgaaagaacttcagttgctgaaacagtgaga
aaatgctggccagctagactcgcaaaggagcagattagtaaacggcttgatggtaatcaa
tatctgtttttaccaccaaaccgttatattttccatggtgctgaggtatattcagactct
gaagatgatgtcttatcctctagttcttgtggcagtaacagtgatagtggaacatgccag
agtccaagtttagaagaacctatggaggatgaaagtgagattgaagaattttacaatggt
ttggaagatgatactgatgttaatgagagcgccggaggaactggatttggagctgatgga
ggtgaacaagaggcagttaatgaagctacatctatgaaacaggaagcaacaagcattaac
tatccatcgaacataatgtaa

DBGET integrated database retrieval system