Physeter macrocephalus (sperm whale): 102993432
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Entry
102993432 CDS
T06011
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
102993432 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
pcad03021
]
102993432 (SETX)
Enzymes [BR:
pcad01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
102993432 (SETX)
5.6.2.5 RNA 5'-3' helicase
102993432 (SETX)
Transcription machinery [BR:
pcad03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
102993432 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
UvrD-helicase
AAA_19
AAA_30
AAA_22
ResIII
AAA_16
Helicase_RecD
SLFN-g3_helicase
UvrD_C_2
nSTAND3
Motif
Other DBs
NCBI-GeneID:
102993432
NCBI-ProteinID:
XP_028353517
Ensembl:
ENSPCTG00005005641
UniProt:
A0A2Y9S3I5
LinkDB
All DBs
Position
13:complement(86122451..86191034)
Genome browser
AA seq
2678 aa
AA seq
DB search
MSTCCWCTPGGISTIDFLQRYASETHSSEFQTADEDLCYCLECVAEYHKARDALPFLHKV
LWELETSRLTNHFEKAMKAEIGDDDELYIVDNNGEAQPFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEEGKLILLPSHMYDTANYKNYWLG
ICMLLTILEEQAMDSLLLGSNKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNKEIQNIRNSSVRTKLEPESYLDDMATCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDILNQTDAVCDTVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTTMISSLSLHSVPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKLKVP
QCSTSVDLTPPCKTPPASYNKEESKQTGKKSKKDRHCLENSSPTFSKEPMKADACQVQES
IFSKANNAIEEDNEQTSIKDLKLEDHLSAELCLKPSSKRLVNERARGQVKISTGKHKSVK
ENSSYTPQNCTSRNGPEKVFDRGIITSTRLLTDSSNDSLEKVSTSNEDFSLKDDTLARTS
KAKTKAHKDEICAKLSHVIKKQHRQSITLEENLTVSSIESFYSKKDTGGHNLSLGPNGIL
DDKNGEQKSENSLLLKNKQVKEEELGIFSTPEISCQILECHVGNKDLVSFTEMTNIFVEK
TPPSKDPVTGLESRDMGISKSTVQFSSNLREHVLSISPKSDTLTDSQIDRDLHKLSLIAQ
ASVIKFPSDSTQKSSSQLQRKVKGDRRCFTANQNSVRETCCRQVIIISDSDEDDDDDDER
IVGFKKHIKQNKTCIEKQCPEQHTSIANTNVEQNVIKEENTRSLLQFEESDSQFFEFESP
CEVFSVWQDQKPDNKNSVQENEENSCLTHVGDITNDWGYDTDYVPEEVIKKAAEGIEEHT
EPHSSSVSVEKFCEIEVKKPKRKRYEKAAMAEDPLRPSSPVKSEDQSDILNERDVTEKDL
KSMGKRTTTPSSSVQRSTTVSLKKSPPKLHAYSRPVRKVAVSKTPKKTHSDTKTAQGKSS
NYISCRTTPAIVPPKKFRQCPEPTSTVEKLHLEKAPHRAFELSQQSLECIRDHGKAVRVV
DTQRKTKLISPQTLSVKNNKKLLTSQDLQLQRQMRPRSQQNRQGCSDDQSTDTARAGPHA
AQNSDKFVPESDTSDYSYKRGVEVTAKRKEKQLIKCLSSETEPVKAKYVSQVADDTCLLN
QCTSVVLNGEIPTNEIVVSASGDPLGGGDLTVHHLDVAALKEGEPESSSDIEEDSIFLTQ
CDPEDMDLCSQMEKENDKLIEVVHGKDTVQVGEDSVSRPQLGSLSSTKCKYKDCVETPEN
QGEYCSKHSESKAADEDIFRKPGLPLSASKPLRPSTAKIFSSSSTSRIAGLSKSLEDTSV
LLPTPKNKSSGVQSVLKVPQPVSLVSQKPVAEVKGLCTVLHSHTPNNSNRQGYKVPFCEN
RSFSPSSPVNILLSAQSISDTFVKEVLKWKYEMFVNFDLCGPPSTLCQSIARPVPVRFQD
CGDYFSVFLPLMILNTFETVAQEWISSPNKEKFHQLHLRKFPSDYKKYWEFVVYLEECEL
AKQLHPKENDLVFLVPESLNGEKRDIERNHMQDPHEYYCGYVHKFRRTSVMRNGKSECSL
SIQTQHNLPVNLNEFVKCLVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMDFCTKDL
LTTTSERIIAYLKDFNEDQKKAIETAYAMVKHSPAVAKICLIHGPPGTGKSKTIVGLLYR
LLTERRGHSYENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDI
NLVRLGPEKSINTEVLKFSLDSQVNHRMKKDLPSHIQEMHRRKEFLDHQLDELSRQRALC
RGGRELQRQELDEEIAKVSEERQELASKIKEVQGRPQKTQNIIILESHIICCTLSTSGGL
LLEAAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQ
EYGYDQSMMARFYKLLEENVEHNVIGRLPILQLTIQYRMHPDICLFPSNYVYNRNLKTNR
MTETIRCSSDWPFQPYLVFDVGDGSEKRDNDSYVNVQEIKLVMEIIKLVKDKRREVTFRN
IGIITHYKAQKTMIQKNLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANAMQGSIGF
LASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIIKTCDKNYRHDAMK
ILKLKPVLQRSLTHPPAVAPEGSRPQGGVPSNKLESEFAKMSFASSLYPSPSDSKEATVT
VTAKDPERPPIQDWLRDPRLLRRMGLGCEAKGKCLGELQPSSPHDPGATPPSGEPGSPRS
HQDPTSIGQQPPAQGAAVNNHRPHAQRNAPAAGTVAATSKRKCAQEGGALSHMSETWAFT
EGAQERRGALSHHPKRSSGWGESGLEKEDSSLKKKKVL
NT seq
8037 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgccaggtggtatttccaccattgacttcctgcaacgg
tatgcatccgagacccactccagtgaatttcaaacagctgatgaagacctctgctactgc
ttagagtgtgtggctgaataccacaaagcacgggatgcgttgccattcttacataaggtt
ttatgggaattagaaacctcacgtctcacaaatcactttgaaaaggccatgaaggcagaa
attggagacgatgacgagttatatatagtagacaacaatggagaggcacagccgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatttgcttttacatgagcgtgttaatgaattatgcgttgaagcactttgccggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccagggatctatttgtttttg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaagaaacttgggaaaa
gtggacagagatgattattatgacttacaggaggttttgacttgcctttttaaagttatt
gagttggggcttttagaaagtccagacatttatacttcttctgtccttgaggagggtaaa
ctgattcttctgccttcacacatgtatgatactgccaactacaaaaactattggttaggt
atttgcatgttgctgaccattcttgaggagcaagccatggattcactgttgttgggctca
aacaaacagaatgattttatgcagtcaatacttcacaccatggagaggcaatcagatgat
gatagtgtggatcctttctggccagcgttacactgtttcatggtgattctggatcgcctt
ggatctaaggtctggggtcaacttattgatcctattgaggcatttcaaaccattatcaac
aatgtgagctacaataaagagatccagaatatacggaacagctctgtgaggaccaagtta
gaaccggagtcatatttggatgatatggcgacttgcagccagattgtatacaattataac
cctgaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagctaatgtgcttcagtcagatattggtcaagac
atgcgtgttcataacagcacgtttctgtggttcatcccttttgtgcagtccctcatggat
cttaaggatctgggtgtggcttatatagtggaggttattcatcatctgcattctgaagtc
aaagacatcctcaaccagacagacgccgtgtgtgacacagtcactgagtttttccttctg
attttggtgtcagtgattgaactgcatagaaataaaaagtgtttgcatttgctgtgggtt
agttcccagcagtgggtggaagccgtcgtaaaatgcgccaagcttcccaccaccgcattt
gcacggagttctgagaagtcgtctggaaactgctccaaaggcacaacgatgatatcatct
ctgtcattgcattcagtgccatctaactctgtacaacttgcttgtgtgcagctgatcaga
agtctccttaaagaaggctatcagcttgggcagcagactctttgtaagcgattctgggat
aagctcaacttattcctgcgaggaaatttatctttaggttggcagttgactagtcaggaa
acccatgagttacaaacttgtttaaagcaaattattagaaacataaaattgaaagtacct
caatgtagcacttctgtggatctgactcctccatgtaaaacgcctcctgcatcttataat
aaagaagaaagtaaacaaacagggaagaagtctaaaaaagacaggcactgtctggaaaac
tccagcccaacgttctctaaagaaccgatgaaagctgatgcgtgtcaagtgcaagagagt
attttcagcaaagcaaataatgccatagaagaggataatgagcaaacttctataaaagat
ttgaaactcgaagaccatctctcagctgagttgtgcttgaagccgagtagtaaaaggctt
gttaatgaaagagctcgaggccaagttaaaataagtacagggaagcataagtctgtaaaa
gagaattcctcatataccccacagaattgtacttcaagaaatggtccagaaaaggtattt
gacagaggaataataacatcaacacgtttgttgactgattctagcaatgactctctggaa
aaggtgtccacatcaaatgaggatttctctttaaaggatgatactcttgccagaacctca
aaggcaaaaactaaggcacataaagatgaaatctgtgctaagttatcacatgtaataaaa
aagcaacacaggcaaagtatcactttagaggaaaacctgactgtatctagcattgaaagt
ttctattcaaagaaagatacaggaggtcacaatctctctttaggccctaatggtattctg
gatgataaaaatggagaacaaaaatctgaaaacagtttattgctgaaaaacaaacaagta
aaggaagaagagttaggcattttctctacccctgaaatcagttgtcaaatactagaatgt
catgttggtaataaagatttggtctcatttacagaaatgaccaatatttttgtggagaaa
acacctccctctaaagatcctgtgactggacttgaatcaagagatatgggaattagcaag
agtactgttcagttttcttccaatttaagagaacatgtccttagcatcagtcctaagtct
gacaccttaacagattctcagatagacagagacctccacaaattatctttaatagctcaa
gccagtgttattaagttcccatcagattcaactcaaaaaagttcatcccagctacaaaga
aaagttaaaggtgatagaagatgtttcacagccaaccaaaatagtgtcagggaaacctgc
tgtagacaggttattattatttcagattctgatgaagatgatgatgatgatgatgaaaga
attgtgggttttaagaaacacattaaacagaataaaacatgcatcgagaagcaatgtcca
gagcagcatacttcaatagctaacacaaatgtggaacagaatgtaataaaggaagaaaat
acaaggtcccttttgcagtttgaggaatctgattctcagttttttgagtttgaaagtcca
tgtgaagtgttttcagtttggcaagatcagaaaccagacaacaagaattcagttcaagag
aatgaagaaaattcgtgcttgactcacgtaggtgatatcacaaatgattggggttatgat
acagattatgtacctgaagaggtcattaaaaaagcagcagagggcattgaggaacacaca
gagccacacagtagtagtgtttctgttgagaaattttgtgaaattgaggtaaaaaaaccc
aagagaaaacgatacgagaaagctgctatggctgaagatcctctaaggccttcatctcct
gtcaaaagtgaggaccagtctgatattcttaatgagagagatgtgactgaaaaggattta
aaaagtatgggcaagaggactacaactcccagttcaagtgttcagaggagcactacggtt
tccctgaagaagtctccaccaaagcttcacgcttactccagacctgttaggaaagtcgca
gtttctaaaactcctaaaaaaacacattcggataccaaaacagcgcagggtaaaagttca
aattacataagttgtagaacaactcctgctatagtgcccccaaagaaatttcgtcagtgt
cctgaaccaacttcaacggttgagaaacttcatctggaaaaggctcctcatagggcattt
gagttgtcccagcaatctttggagtgtatacgtgaccatggcaaagctgttcgagtagtt
gatacccagagaaagactaaattaatttctcctcagactctctctgtcaaaaataataag
aaactgctgacgagtcaagaccttcagctgcaaaggcagatgagacccagatcacagcaa
aacagacaaggatgttctgatgatcaaagtacagatacagcacgagcagggccacatgca
gcgcagaattctgacaaatttgtgccagaatcagatacatcagattatagttataaaaga
ggagttgaagtaactgctaaacgtaaggaaaaacagttaataaaatgtctgtcttctgaa
acagaacccgtgaaagcaaaatacgtttctcaggtagctgatgacacttgtcttttgaac
cagtgtacttctgtagtgttaaatggagaaataccaacaaatgaaatagttgtttctgcc
tcaggggaccctttaggtggaggtgacctaacagtacatcatttagatgtggcagctttg
aaggagggagagcctgaatccagcagtgacatagaggaagatagtatatttttaacacaa
tgtgatcctgaagatatggatttatgttcacaaatggagaaagagaatgataaactcatt
gaagtagttcatggaaaagatacagtccaggtaggagaagattctgtgagtcggcctcag
ttgggatctttgagtagcacaaaatgtaagtacaaagattgtgttgaaacaccggaaaac
cagggtgaatactgttcaaaacactctgaatctaaagcagcagatgaagatatatttcgt
aaacctggcttgcctctctctgcatctaaacctttgagaccttccactgctaagattttt
agctccagtagtacttcacgaattgctggtctttccaagtctttggaagatacatcagtg
ctcttaccaactccgaaaaataagtcaagtggggtacagtctgttttgaaagtaccacag
ccagtatctctcgtatctcagaagccagtggctgaagtgaagggtttgtgcaccgttctc
cattctcatactccaaataattccaacaggcaaggctacaaagttccattttgtgaaaac
agatctttttcgccttcctctccagtaaacattctcttgtcagcacagtccatctctgac
accttcgttaaagaggtcttaaaatggaaatatgaaatgtttgtgaactttgatctgtgc
ggacccccgtcaactctttgtcagtccatcgcaagacctgtgcctgtgagatttcaagat
tgtggagattattttagtgtgtttctccctttgatgatactgaatacttttgaaacagtg
gcacaggaatggatcagctctccaaacaaagagaaattccatcagttacatttacgaaaa
tttccttctgattataaaaaatactgggagtttgtggtttatcttgaggaatgtgaacta
gctaaacagcttcatccaaaggaaaatgatttggtgtttttggttcctgaaagcctaaat
ggagagaagagggatatagagagaaatcacatgcaggatccccatgaatattattgtggt
tatgttcataaattccgccgcacttcagtcatgcgtaatgggaaatctgagtgttccctt
tccatccagactcaacataatttaccagtcaatttaaatgaattcgtgaaatgtcttgta
atcagctctctggtgactacacaaaggaagttgaaagccatgtctttgctgagtggtcgg
aaccaactggccagagccgttctgaatccaaaccccatggacttctgtacaaaagattta
ctaactacaacatctgagagaattattgcctacctaaaagatttcaatgaagaccaaaag
aaagcgatagaaactgcatatgccatggtgaaacactccccagcagttgccaagatctgt
ctgattcatggaccacccgggacaggaaaatcaaaaaccattgtgggcctcctgtaccgc
ctactgacagagaggagggggcattcatatgagaactccaatgccaaaatcaaacaaaac
cgtgtccttgtgtgtgcgccttccaatgcagctgttgatgaacttatgaaaaaaattatc
cttgaattcaaagagaagtgtaaagacaagaagaatcctttgggaaactgtggagatata
aatttagtacgtctaggtccagaaaagtctattaatactgaggtcctaaaattcagtttg
gacagccaagttaaccacagaatgaaaaaagacttaccttctcatattcaggagatgcat
agaagaaaggaatttctagatcatcaactagatgaactttcccgccagcgtgctttatgc
cgaggtggaagggaactacagaggcaagaattagatgaagaaattgccaaagtttcagaa
gaaaggcaggagcttgcttctaaaattaaagaggttcaaggacgcccacaaaagacacag
aacatcatcatcttagagtcccacatcatctgctgcacactgagcacgagtggtggtctg
ctgctcgaggctgctttccgtgggcaagggggtgtcccctttagttgcgtcattgttgat
gaggccggacagtcctgtgaagttgaaactcttactccgctcatccatcgctgcaacaag
ctcatcctcgtaggggatcctaagcagctccctcctaccgtcatttctatgaaggcccag
gagtatggctatgaccagtcgatgatggcccgcttctacaaacttctggaagagaacgtg
gagcacaacgtgattggcaggctgcctatcttacagctcaccattcagtacaggatgcac
ccagacatatgtctcttcccttctaattacgtttataacagaaacttgaaaacaaataga
atgacagagaccattcggtgttcatctgactggccatttcaaccctacctcgtgtttgat
gttggagatggttcagaaaagcgggataatgactcatatgtaaatgttcaagaaataaaa
ctggtaatggaaataattaaacttgtgaaagacaaaagaagggaagttactttccgaaac
attggcataataacccattacaaggctcagaagacgatgattcagaagaatttggacaaa
gagtttgatagaaaagggccagcagaagtagataccgtggatgccttccagggtcgtcag
aaagattgtgttattgttacatgtgtcagagcaaatgccatgcaaggctcaattgggttt
ctggcaagtttgcagagattgaatgtcaccatcacacgagccaagtacagcctcttcatc
ctgggacatttgaggaccctgatggaaaaccagcattggaatcacctgattcaggacgcg
cagaagcgtggtgccattattaagacttgcgacaaaaactatagacacgatgcaatgaag
attctgaaactgaagcccgtactgcagagaagtctgactcaccctcctgctgtcgcccca
gaggggtccagaccccagggcggagtgcccagcaacaagctagagagtgaatttgccaag
atgtcttttgcttcttccctgtacccctcaccctctgactccaaagaagccactgtcact
gttactgcaaaggaccctgaaaggccacctattcaggactggcttcgggacccacgactg
cttaggaggatgggcttgggctgtgaggccaaagggaaatgcctcggtgagctgcagccc
tcgagcccccatgatcccggggcaacgcctccctcgggagagccaggctcccccagaagt
caccaggatccgaccagtatcgggcagcagccccccgcccagggagctgccgtgaacaac
cacagacctcacgcacagcgcaacgccccagctgctggtaccgttgctgccacgagtaag
agaaaatgtgcccaggaagggggagcgctcagccacatgtcggagacctgggccttcact
gagggcgctcaggagaggcgcggcgctctgagccaccacccaaagaggagctcgggctgg
ggcgagagcgggctggagaaggaggacagtagcttgaagaagaagaaggttttgtag
DBGET
integrated database retrieval system
