KEGG   Physeter macrocephalus (sperm whale): 102993806
Entry
102993806         CDS       T06011                                 
Symbol
HDAC2
Name
(RefSeq) histone deacetylase 2 isoform X3
  KO
K06067  histone deacetylase 1/2 [EC:3.5.1.98]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad03082  ATP-dependent chromatin remodeling
pcad03083  Polycomb repressive complex
pcad04110  Cell cycle
pcad04213  Longevity regulating pathway - multiple species
pcad04330  Notch signaling pathway
pcad04350  TGF-beta signaling pathway
pcad04613  Neutrophil extracellular trap formation
pcad04919  Thyroid hormone signaling pathway
pcad05016  Huntington disease
pcad05031  Amphetamine addiction
pcad05034  Alcoholism
pcad05165  Human papillomavirus infection
pcad05169  Epstein-Barr virus infection
pcad05200  Pathways in cancer
pcad05202  Transcriptional misregulation in cancer
pcad05203  Viral carcinogenesis
pcad05206  MicroRNAs in cancer
pcad05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    102993806 (HDAC2)
   03083 Polycomb repressive complex
    102993806 (HDAC2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    102993806 (HDAC2)
   04350 TGF-beta signaling pathway
    102993806 (HDAC2)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    102993806 (HDAC2)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    102993806 (HDAC2)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    102993806 (HDAC2)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    102993806 (HDAC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102993806 (HDAC2)
   05202 Transcriptional misregulation in cancer
    102993806 (HDAC2)
   05206 MicroRNAs in cancer
    102993806 (HDAC2)
   05203 Viral carcinogenesis
    102993806 (HDAC2)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    102993806 (HDAC2)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    102993806 (HDAC2)
   05165 Human papillomavirus infection
    102993806 (HDAC2)
  09164 Neurodegenerative disease
   05016 Huntington disease
    102993806 (HDAC2)
  09165 Substance dependence
   05031 Amphetamine addiction
    102993806 (HDAC2)
   05034 Alcoholism
    102993806 (HDAC2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:pcad03036]
    102993806 (HDAC2)
Enzymes [BR:pcad01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     102993806 (HDAC2)
Chromosome and associated proteins [BR:pcad03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     102993806 (HDAC2)
   HDAC complexes
    Sin3A-HDAC complex
     102993806 (HDAC2)
    BRAF-HDAC complex
     102993806 (HDAC2)
    REST complex
     102993806 (HDAC2)
    SHIP complex
     102993806 (HDAC2)
    MiDAC complex
     102993806 (HDAC2)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     102993806 (HDAC2)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    102993806 (HDAC2)
  Chromatin remodeling factors
   NuRD complex
    102993806 (HDAC2)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 102993806
NCBI-ProteinID: XP_023971341
Ensembl: ENSPCTG00005014660
UniProt: A0A2Y9RXT7
LinkDB
Position
10:47288596..47329688
AA seq 488 aa
MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA
TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA
GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH
GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQ
IFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLG
GGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYM
EKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEE
FSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGA
KSEQLSNP
NT seq 1467 nt   +upstreamnt  +downstreamnt
atggcgtacagtcagggaggcggcaagaagaaagtctgttactactacgatggtgatatt
ggaaattattattacggacagggtcatcccatgaaacctcataggatccgcatgacccat
aacttgctgctaaattatggcttgtatagaaaaatggaaatatataggccccataaagcc
actgctgaagaaatgacaaaataccacagcgatgagtacatcaaatttctacgttcaata
agaccggataacatgtccgagtatagtaagcaaatgcagagatttaatgttggagaggat
tgtccagtgtttgatgggctctttgagttttgtcagctttcaactggtggttcagttgct
ggggctgtgaagttaaaccgacaacaaactgatatggctgttaactgggctggaggatta
catcatgctaagaaatcagaagcatcaggattctgttatgttaatgatattgtgcttgcc
atccttgaattactaaaatatcatcagagagtcttgtatattgatattgatatccatcat
ggtgatggtgttgaagaagctttttatacaacagatcgtgtaatgactgtatcattccat
aaatatggggaatactttcctggaacgggagacttgagggatattggtgcaggaaaaggc
aaatactatgctgtcaattttccaatgagagatggtatagacgatgaatcatatgggcag
atatttaagcctattatctcaaaagtgatggagatgtatcaacctagtgctgtggtgcta
cagtgtggtgcagactcactatccggtgatagacttggttgcttcaatttgacagtcaaa
ggtcatgctaaatgtgtagaagttgtaaaaactttcaatttaccattactgatgcttggg
ggaggtggatacacaatccgcaatgttgctcgatgttggacatatgagactgctgttgcc
cttgattgtgagattcccaatgaattgccatataatgattactttgagtattttggacca
gacttcaaactgcatattagtccttcaaacatgacaaaccagaacactccagaatatatg
gaaaagataaaacagcgtttatttgaaaatttacgcatgttaccacatgcacctggcgtc
caaatgcaagctattccagaagatgcagttcatgaagacagtggagatgaagatggagaa
gatccagacaagagaatttctattcgagcatcagacaaacggatagcttgtgatgaagaa
ttctcagattctgaggatgaaggagagggaggtcgtagaaatgtggctgatcataagaaa
ggagcaaagaaagctagaattgaagaagacaagaaggaaacggaggacaaaaaaacagat
gttaaagaagaagataaatccaaggacaatagtggtgaaaaaacagataccaaaggagcc
aaatcagaacagctcagcaatccttga

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