KEGG   Physeter macrocephalus (sperm whale): 102994051
Entry
102994051         CDS       T06011                                 
Symbol
ITGA2B
Name
(RefSeq) integrin alpha-IIb isoform X5
  KO
K06476  integrin alpha 2B
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad04015  Rap1 signaling pathway
pcad04151  PI3K-Akt signaling pathway
pcad04510  Focal adhesion
pcad04512  ECM-receptor interaction
pcad04611  Platelet activation
pcad04613  Neutrophil extracellular trap formation
pcad04640  Hematopoietic cell lineage
pcad04810  Regulation of actin cytoskeleton
pcad04820  Cytoskeleton in muscle cells
pcad05165  Human papillomavirus infection
pcad05200  Pathways in cancer
pcad05222  Small cell lung cancer
pcad05410  Hypertrophic cardiomyopathy
pcad05412  Arrhythmogenic right ventricular cardiomyopathy
pcad05414  Dilated cardiomyopathy
pcad05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102994051 (ITGA2B)
   04151 PI3K-Akt signaling pathway
    102994051 (ITGA2B)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    102994051 (ITGA2B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102994051 (ITGA2B)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    102994051 (ITGA2B)
   04810 Regulation of actin cytoskeleton
    102994051 (ITGA2B)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    102994051 (ITGA2B)
   04611 Platelet activation
    102994051 (ITGA2B)
   04613 Neutrophil extracellular trap formation
    102994051 (ITGA2B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102994051 (ITGA2B)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    102994051 (ITGA2B)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    102994051 (ITGA2B)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    102994051 (ITGA2B)
   05410 Hypertrophic cardiomyopathy
    102994051 (ITGA2B)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    102994051 (ITGA2B)
   05414 Dilated cardiomyopathy
    102994051 (ITGA2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pcad01009]
    102994051 (ITGA2B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pcad04147]
    102994051 (ITGA2B)
   04515 Cell adhesion molecules [BR:pcad04515]
    102994051 (ITGA2B)
   04090 CD molecules [BR:pcad04090]
    102994051 (ITGA2B)
Protein phosphatases and associated proteins [BR:pcad01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     102994051 (ITGA2B)
Exosome [BR:pcad04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   102994051 (ITGA2B)
Cell adhesion molecules [BR:pcad04515]
 Integrins
  Integrin alpha subunits
   102994051 (ITGA2B)
CD molecules [BR:pcad04090]
 Proteins
  102994051 (ITGA2B)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_2 Integrin_A_Ig_1 FG-GAP FG-GAP_3 Integrin_alpha ITGAX-like_Ig_3
Other DBs
NCBI-GeneID: 102994051
NCBI-ProteinID: XP_007127991
Ensembl: ENSPCTG00005018981
UniProt: A0A2Y9FR54
LinkDB
Position
Unknown
AA seq 1034 aa
MARALCPLHALWVLEWVQLLLGPGAAPPTWALNLDQVRLTFYTGPNGSYFGFSLDFYKDS
RGSVSIVVGAPRTLGRSQEETGGVFLCPWKAEGDQCTSLPFDLNDETRSVGTQTFQTFKA
RQGLGASVVSWSDIIVACAPWQHWNVLEKAEEAEKTPVGGCFVAQLQNGGRAEYSPCRAN
IMSRVYEKNYFSGDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLARAPIADIISSYRP
ATLLWHVPTQQLTFDYSHPEYFDGYRGYSVAVGDFDGNPNTTEFVFGAPTWSWTLGAVEI
LDSYHQTLHRLHGEQMASYFGHSVAVTDVNRDGRHDLLVGAPLYMESRADLKLAEVGRVY
LFLQTRGPHALGAPSLRLTGTQLYGRFGSAIAPLGDLNRDGYNDVAVAAPYGGPSGRGQV
LVFLGQSEGLNSHPSQVLDSPFPTGSGFGFSLRGATDIDDNGYPDLLVGAYRANKIVVYR
AQPVVMATLQLLVQDSLNPAVKNCVLPQTETPVSCFNIQMCVGATGHNVPKKLRLNAELQ
LDRQKPRQGRRVLLLASQQAGTILDLDLSGRHGPTCHTTKAFLRDEADFRDKLSPIVLSF
NVSLQPERDGLAPALMLHGDTHIQEQTRIILDCGEDDLCVPQLQLTASVTGSPLLIGADN
VLELQMEAANEGEGAYEAELAVHLPPGAHYMRALSNIEGFERIICNQKRENETKVVLCEL
GNPMKRNAQIRITMLVSVGNLEEAGEHVSFRLQIRSKNSQNPNSEMVMLDVPVRAEAHVE
LRGSSFPASLVVAAEEGKRENSSDSWGPKVEHTYELHNNGPGAVNGLRLNLHLPGQSQPS
DLLYILDIQPRGGLQCSPQPSPNPLKLDWGLPTSSPSPAHHKRDRRQALLPEQEQPSRLQ
GPVFVSCDSAPCTVVQCELQEMARGQRVMVTVLAFLSLPSLRQRPLDQFVLQSHAWFNVS
SLPYAVPALSLPSGEALVQTQLLRVLEERDIPIWWVLVGVLGGLLLFTFLVLAMWKVGFF
KRNRPPLEEDDEEE
NT seq 3105 nt   +upstreamnt  +downstreamnt
atggccagagctttgtgtccacttcatgccctctgggttctggagtgggtgcagctgctc
ttgggacccggtgctgcacctccaacctgggccttgaacctggaccaagtgcgactcacc
ttctacacaggccccaatggcagctactttgggttttcattggacttctacaaggacagc
cgtgggagcgtgtccatcgtggtgggcgccccacggaccctgggccgcagccaggaggag
acaggcggcgttttcctgtgcccctggaaggccgagggcgaccagtgtacctcgctgccc
ttcgacctcaatgatgagacgcgaagcgtaggcacccaaactttccaaaccttcaaggcc
cgtcaaggactaggggcgtcggtcgttagctggagcgacatcattgtggcctgcgcccca
tggcagcactggaacgtcctggaaaaggccgaggaggctgagaagacgcccgtaggtggc
tgcttcgtggctcagctgcagaacggcggccgcgcggagtactcaccctgccgggccaac
atcatgagccgggtttacgagaaaaattacttcagcggagacaagcgctactgtgaagcc
ggcttcagctccgtggtcactcaggctggggagctggtgcttggggcccctggcggctac
tatttcctaggtctcctggcgcgggctccaattgccgatatcatctcgagttaccgcccg
gctaccctcttgtggcacgtgcccacccagcagctcaccttcgactacagccacccagag
tacttcgacggctaccgggggtactcggtggctgtaggcgacttcgacgggaatccaaac
actacagagtttgtcttcggtgcccctacctggagctggaccctgggagcggtggaaatt
ttggactcgtaccaccagacgctgcaccggctgcacggagagcagatggcttcgtatttc
gggcactcagtggccgtcactgacgtcaacagggacgggaggcatgacctcttggtgggc
gcgccactgtacatggagagccgtgctgacctcaagctggccgaggtggggcgcgtgtac
ttgttcctgcagactcgaggccctcacgcgctgggcgcccccagcctccggctgaccggc
acgcagctctatgggcgatttggctcagccatcgcgcctctgggcgacctcaaccgggat
ggctacaacgatgttgctgtggccgccccctatgggggtcccagcggtcgaggccaagtg
ttggtgttcctgggtcagagtgagggacttaactcacacccttcccaggtcctggacagc
cccttccccacaggctctggctttggcttctcccttcgaggtgccacagacatcgatgac
aatggatacccagacctgctggtgggagcttacagggccaacaagattgtagtgtacagg
gctcagccggtggtgatggccactctccagctgctggtgcaagattcgctgaatcctgct
gtgaagaactgtgtcctgccccagaccgagacaccagtgagctgctttaatatccagatg
tgtgtgggagccactggacacaacgttcccaagaagctgcgcctaaatgccgagctgcag
ctggaccggcagaagccccgccagggccggcgggtgctactgctggcctctcaacaggcg
ggcaccatcctggacctggatctgagcgggaggcacggccccacctgccacaccaccaag
gccttcctccgagatgaggccgacttccgggacaaactgagccccatcgtgctcagcttc
aatgtgtccctgcagcctgagagggatggactagcccctgctctcatgttgcatggagac
acccacatccaggaacagacccgcatcattctggactgtggggaagacgacctgtgtgtg
ccacagctccagctcactgccagcgtgacaggctccccgctcctcattggagccgataac
gtgctggagctgcagatggaagcggccaacgagggtgagggagcctacgaggccgagctg
gctgtgcacctgcctccaggcgcacactatatgcgggccctcagcaacatcgagggcttt
gagaggatcatctgtaaccagaagagggagaatgagaccaaggtggtgctgtgtgagctg
ggcaaccccatgaagaggaacgcccagataagaatcacgatgttggtgagtgtggggaac
ctggaagaggctggggagcacgtgtccttccggctgcagataaggagcaagaacagccag
aatcccaacagtgagatggtgatgctggatgtgccagttcgggcagaggcccatgtggag
ctgagagggagctcctttccagcctccctggtggtggcagcagaagaaggcaagagggag
aacagctcggacagctggggccccaaagtggagcacacctatgagctccacaacaatggc
cctggtgctgtaaatggcctccgcctcaacctccacctccccggccagtcgcagccctcc
gaccttctctacatcctggatatacagccccggggaggccttcagtgctccccacaaccg
tctcccaaccccctcaagctggactgggggctgcccacctccagcccttccccagcccat
cacaagcgggaccgcagacaggcactcctgccagagcaggagcagccctcgaggcttcaa
ggtccagtttttgtgagctgcgattcggcgccctgtactgtggtgcagtgtgagctgcag
gagatggcgcgcgggcagcgggtcatggtcacggtgctggccttcctgtcgctgcccagc
ctccgccagaggcccctggatcagtttgtgctgcagtcgcacgcttggttcaacgtctcc
tcccttccctacgccgtgcccgccctcagcctgcccagcggggaagctctggtgcagaca
cagctgcttcgggtcttggaagagagagacattccaatctggtgggtgctggtaggcgtg
ctgggtggcctgctgttgttcacgttcctggtcctggccatgtggaaggttggcttcttc
aagcggaatcggccacccttagaagaagatgatgaagaggagtga

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