Physeter macrocephalus (sperm whale): 102994071
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Entry
102994071 CDS
T06011
Symbol
LRP6
Name
(RefSeq) low-density lipoprotein receptor-related protein 6 isoform X1
KO
K03068
low density lipoprotein receptor-related protein 5/6
Organism
pcad
Physeter macrocephalus (sperm whale)
Pathway
pcad04150
mTOR signaling pathway
pcad04310
Wnt signaling pathway
pcad04928
Parathyroid hormone synthesis, secretion and action
pcad05010
Alzheimer disease
pcad05022
Pathways of neurodegeneration - multiple diseases
pcad05200
Pathways in cancer
pcad05224
Breast cancer
pcad05225
Hepatocellular carcinoma
pcad05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
pcad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
102994071 (LRP6)
04150 mTOR signaling pathway
102994071 (LRP6)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
102994071 (LRP6)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102994071 (LRP6)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102994071 (LRP6)
05226 Gastric cancer
102994071 (LRP6)
05224 Breast cancer
102994071 (LRP6)
09164 Neurodegenerative disease
05010 Alzheimer disease
102994071 (LRP6)
05022 Pathways of neurodegeneration - multiple diseases
102994071 (LRP6)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pcad04131
]
102994071 (LRP6)
Membrane trafficking [BR:
pcad04131
]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
102994071 (LRP6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ldl_recept_b
FXa_inhibition
Ldl_recept_a
Vgb_lyase
DUF5050
SGL
EGF_LRP2
cEGF
EGF
Motif
Other DBs
NCBI-GeneID:
102994071
NCBI-ProteinID:
XP_023984727
Ensembl:
ENSPCTG00005008896
UniProt:
A0A2Y9T543
LinkDB
All DBs
Position
6:complement(60962086..61151475)
Genome browser
AA seq
1614 aa
AA seq
DB search
MGAVLRSLLACSFCVLLRAAPLLLYANRRDLRLVDAANGKENATIVVGGLEDAAAVDFVF
GHGLIYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIE
VSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFIIINTE
IYWPNGLTLDYQERKLYWADAKLNFIHRSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWT
DWNTHSILACNKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMS
PVKPFYQCACPTGVKLLENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIR
HAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWT
DTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWGEIPKIERAALDGSD
RVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTL
LGDYVYWTDWQRRSIERVHKRSAEREIIIDQLPDLMGLKATNVRRIIGSNPCAEENGGCS
HLCLYRPQGLRCACPIGFELISDTKTCIVPEAFLLFSRRADIRRISLETNNNNVAIPLTG
VKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLY
WADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDG
SERTTLVPNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQ
YQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHC
SHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILP
IHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSVPNQNLEIQPYDLS
IDIYSRYIYWTCEATNVINVTRLDGRSIGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERS
PKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLE
DSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQ
EYRQHPCTQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELLCGEPPTCSPQQFTCFTGE
IDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEK
NCEVLCLIDQFRCANGQCVGKHKKCDHNLDCSDKSDELDCYPTEEPAPQATNTVGSVIGV
IVTIFVSGTIYFICQRMLCPRMKGDGETMTNDYVVHGPASVPLGYVPHPSSLSGSLPGMS
RGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTM
EFGYSSNSPSTHRSYSYRPHSYRHFAPPTTPCSTDVCDSDYAPSRRIMTSVATAKGYTSD
LNYDSEPVPPPPTPRSQYLSAEENYESCPPSPYTERSYSHHLYPPPPSPCTDSS
NT seq
4845 nt
NT seq
+upstream
nt +downstream
nt
atgggggccgtcctgaggagcctcctggcctgcagtttctgcgtgctcctgagagcggcc
cctttgttgctttatgcaaacagacgggacttgcgattggttgatgctgcaaatggcaaa
gagaatgctacgattgtagttggaggcttggaggatgcagctgcggtggactttgtgttt
ggtcatggcttgatatactggagtgatgtcagcgaagaagccattaaacgaacagagttc
aacaaaactgagagtgtacagaatgttgttgtttctggattattgtcccctgatgggctg
gcatgtgattggcttggagaaaaattgtactggacagattctgaaactaatcgtattgaa
gtttctaatttagatggatctttacgaaaagttttattttggcaagagttggatcaacct
agagctattgccttagatccttcaagtgggttcatgtactggacagattggggagaagta
ccaaagatagaacgtgctggaatggatggttcaagtcgcttcattataataaacactgaa
atttactggccaaatggactgactttggattatcaggaacggaagctttattgggcagac
gcaaaacttaatttcatccacagatcaaatctggatggaacaaatcggcaggcggtggtt
aaaggttcccttccacatccttttgccttgacgttatttgaggacacattgtactggact
gactggaatacacactccattttggcttgcaacaagtacactggcgagggtctgcgtgaa
atccattctaacatcttttctcccatggatatacatgccttcagccagcagaggcagcca
aatgctacaaatccatgtgggattgataatggtggttgttcccacttgtgtttgatgtct
ccagtcaagcctttttatcagtgtgcttgcccaactggggttaaactcctggagaatgga
aaaacctgcaaagatggtgccactgaattactgcttttagcccgaaggacagatctgaga
cgaatttctttggatacaccagatttcacagacattgttctacagttggaagacatccgt
catgccattgccatagattatgatcctgtggaaggctatatctactggactgatgatgaa
gtgagggccatacgccgctcattcattgatggatctggcagtcagtttgtggtcactgct
caaatcgcccatcctgatggtattgctgttgattgggttgcccgaaatctttattggaca
gacactggcactgatcggatagaagtgacaaggctcaacgggaccatgaggaagatcttg
atttcagaggacttagaggaaccccgggctattgtgttagatcccatggttgggtacatg
tattggactgactggggagaaatcccgaaaattgagcgagcagctctggatggttctgat
cgagtagtgttggttaacacttctcttggttggccaaatggtttagccttggattatgat
gaaggcaaaatatactggggagatgccaaaacagacaaaattgaggttatgaataccgat
gggactgggagacgagtgctagtggaagacaaaattccccacatatttgggtttactttg
ttgggtgactatgtttactggactgactggcagaggcgtagcatcgaaagagtacacaaa
cgaagtgcagagcgggaaatcatcatagaccagctccctgacctcatgggcctgaaggcc
acaaatgttcgtcgaatcattggttccaacccctgcgctgaggagaatgggggatgtagc
catctctgcctctacagacctcagggccttcgctgtgcctgccccattggctttgagctc
atcagtgacacgaagacctgcattgtcccagaggctttccttctgttttcacggagagca
gatatcaggagaatttctttggaaactaacaataataacgtggccatcccgctcactggt
gtcaaagaagcttctgctctggattttgatgtgacagacaaccgaatttactggactgac
atatcactcaagaccatcagcagagcctttatgaatggcagtgcactggaacatgtggta
gaatttggcttagattatccagaaggcatggcagtagactggcttgggaagaacttgtac
tgggcagacacaggaacaaatcgaattgaggtatcaaagttggacgggcagcaccgacaa
gttttggtgtggaaagacctagatagtcccagagctcttgcattggaccccgctgaagga
tttatgtattggactgaatggggtggaaagcctaagatagacagagctgccatggatgga
agtgaacgtactacattagttccaaatgtggggcgagcaaatggcctaactattgattat
gctaaaaggaggctttattggacagacctggacaccaacttaatagaatcttcaaatatg
cttggactcaaccgtgaggttatagcagatgacttgcctcatccttttggcttaactcag
taccaagattacatctactggacggactggagccgacgcagcatcgagcgtgccaacaag
actagtggccaaaaccgcaccatcattcagggccatttggattatgtgatggacatcctc
gtgtttcactcctctcggcaggcagggtggaatgagtgtgcttccagcaatgggcactgc
tcccacctctgcttggcagtgccagttggaggttttgtttgtggatgccctgcccactac
tctcttaatgctgacaacaggacttgtagtgctccaactactttcctgctcttcagtcaa
aagagcgccatcaaccgcatggtgattgatgaacagcagagccctgacatcatccttcct
atccacagccttcggaatgtccgggccattgactatgacccactggacaagcaactctat
tggattgactcacgacaaaacatgatccgaaaagcacaagaagatggcagccagggcttt
actgtggttgtgagctcagttccgaatcagaacctagaaatacagccctatgacctcagc
attgatatttatagccgctacatctattggacttgcgaggccaccaatgtcattaatgta
acaagattagatgggagatcgattggagtggtgttaaaaggcgagcaagacagacctcga
gccattgtggtaaacccagaaaaagggtatatgtattttaccaatcttcaggaaaggtct
cccaaaattgaacgagctgctttagatggaacagaacgggaggtcctctttttcagtggc
ttaagtaaaccaattgctttagctcttgatagcagattgggcaaactcttttgggctgat
tcagatctccggcgaattgaaagcagtgatctctcaggtgccaaccggatagtattagaa
gactccaacattctgcagcctgtgggactaactgtgtttgaaaactggctatattggatt
gataagcagcagcagatgattgaaaaaattgacatgacaggtcgagagggtagaaccaaa
gtccaggctcgaattgcccagcttagtgacattcatgcagtaaaggagctgaatcttcag
gaatatagacagcacccttgtactcaggataatggtggctgttcacatatttgtcttgta
aagggagatggtactacaaggtgctcctgccccatgcacttggttctgcttcaggatgag
ctactatgtggagaacccccaacatgttctcctcagcagtttacttgtttcacgggagaa
attgactgtatccctgtggcttggcggtgcgatgggtttactgaatgtgaagatcacagt
gatgagctcaattgtcctgtgtgctcagagtcccagttccagtgtgccagtgggcagtgt
attgatggtgccctgagatgcaatggagatgccaactgccaggataagtcagatgagaag
aactgtgaagtgctttgcttaattgatcaattccgctgcgccaatggtcagtgcgttgga
aaacacaagaaatgtgatcataatttagattgcagtgacaaatcagatgaactggattgt
tatccaactgaggagccagcaccacaggccaccaatacagttggttcagttattggagta
attgttaccatttttgtgtctggaaccatatactttatttgccagaggatgttgtgtcca
cgtatgaagggcgatggggaaaccatgactaatgactatgtagttcatggaccagcttct
gtgccccttggttatgtgccacacccaagctctttgtcaggatctcttccaggaatgtct
cgaggtaaatcaatgataagctccctcagtatcatggggggaagcagtggacccccttat
gaccgagctcatgtcacaggagcatcgtcaagtagttcttcaagcaccaaaggcacttac
ttccctgcaattttgaaccctccgccatccccggccacagagcgatcacattacactatg
gaatttggttattcttcaaacagtccttccactcataggtcctacagctacaggccgcac
agttaccggcactttgcaccgcccaccacaccctgcagtacagatgtttgtgacagtgac
tacgctcccagccggagaataatgacctcagtggccacagccaagggctacactagtgac
ttgaactatgactcagagcctgtgcctccgcctcccacgccccgaagccagtacttgtcg
gcagaagagaactatgaaagctgcccaccttctccatacacagagaggagctactctcat
cacctctacccaccgccgccctctccctgtacagactcctcctga
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integrated database retrieval system
