KEGG   Physeter macrocephalus (sperm whale): 809418
Entry
809418            CDS       T06011                                 
Symbol
ND1, KEF67_p13
Name
(RefSeq) NADH dehydrogenase subunit 1
  KO
K03878  NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad00190  Oxidative phosphorylation
pcad01100  Metabolic pathways
pcad04714  Thermogenesis
pcad04723  Retrograde endocannabinoid signaling
pcad05010  Alzheimer disease
pcad05012  Parkinson disease
pcad05014  Amyotrophic lateral sclerosis
pcad05016  Huntington disease
pcad05020  Prion disease
pcad05022  Pathways of neurodegeneration - multiple diseases
pcad05208  Chemical carcinogenesis - reactive oxygen species
pcad05415  Diabetic cardiomyopathy
Module
pcad_M00142  NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    809418 (ND1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    809418 (ND1)
  09159 Environmental adaptation
   04714 Thermogenesis
    809418 (ND1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    809418 (ND1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    809418 (ND1)
   05012 Parkinson disease
    809418 (ND1)
   05014 Amyotrophic lateral sclerosis
    809418 (ND1)
   05016 Huntington disease
    809418 (ND1)
   05020 Prion disease
    809418 (ND1)
   05022 Pathways of neurodegeneration - multiple diseases
    809418 (ND1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    809418 (ND1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:pcad03029]
    809418 (ND1)
Enzymes [BR:pcad01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     809418 (ND1)
Mitochondrial biogenesis [BR:pcad03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    809418 (ND1)
SSDB
Motif
Pfam: NADHdh
Other DBs
NCBI-GeneID: 809418
NCBI-ProteinID: NP_062467
UniProt: Q9MET6
LinkDB
Position
MT:2775..3729
AA seq 318 aa
MFMINILMLTLPILLAVAFLTLVERKTLGYMQLRKGPNIVGPHGLLQPFADAIKLFTKEP
LRPATSSTTMFIIAPMLALILALTMWSPLPMPYPLINMHLGILFMLAMSSLTVYSILWSG
WASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMSGSFTLSALATTQEQLWLLLPLWP
LTMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYANIIMMNMLSTI
LFLGTYHNPYTPELHTTNLILKTLLLTMSFLWIRASYPRFRYDQLMHLLWKSFLPLALAL
CMWHISLPIMTAGTPPQT
NT seq 955 nt   +upstreamnt  +downstreamnt
atgtttataattaacatcctaatactcaccctccccattctcctagccgtggcattccta
accttagtagaacgtaaaaccctggggtatatacagctccgaaaaggaccaaacattgtc
ggcccacatggcttactccaacccttcgccgacgcaattaaactattcaccaaagaaccc
ctacgtccagccacatcctccaccaccatattcatcatcgcacccatactagccctaatc
ctagccctcacgatatgaagccccctgcccataccatatcccctcatcaacatacaccta
ggaatcctatttatactagcaatatccagcctgactgtttattccattctatgatccggc
tgagcctccaactcaaaatatgcactaatcggagctctccgagcagtagcacaaacaatc
tcatacgaagtgacactagccatcatcctcctatcagtcttactaataagcggctccttc
accctatcagcactagccacaacccaagaacaactttgactgctcttgcccctatgacca
ctaaccataatatgatttatctctaccctcgcagaaactaaccgagcccccttcgacctc
acagaaggagaatcagagctggtctctggcttcaacgtagaatatgcagcaggccccttc
gccctcttcttcctagcagaatatgctaacatcatcataataaatatactctcaaccatc
ctattcctaggaacataccacaatccttacacaccagaactacacacaacaaatctcatc
ctcaaaacactactacttacaatatctttcctatgaatccgagcatcctacccccgattc
cgatatgatcaactgatacacctactctgaaaaagttttctccccctagcactagccctc
tgcatatgacacatctcattacccatcataacagcaggaaccccccctcaaacat

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