Mixta calida: C2E16_04225
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Entry
C2E16_04225 CDS
T05419
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pcd
Mixta calida
Pathway
pcd00300
Lysine biosynthesis
pcd00550
Peptidoglycan biosynthesis
pcd01100
Metabolic pathways
pcd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pcd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
C2E16_04225
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
C2E16_04225
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
C2E16_04225
Enzymes [BR:
pcd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
C2E16_04225
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF4685
Motif
Other DBs
NCBI-ProteinID:
AUY24195
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Position
896929..898293
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AA seq
454 aa
AA seq
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MITLSLETLAQITHGTLVGQGDIAISEVTTDTRKVTPGCLFIALQGERFDAHDFADQAMA
SGAAALLVSKRLQINAPQVVVSDTRIALGELAAWVRQQVKTRVVALTGSSGKTSVKEMTA
AILRQCGETLYTAGNLNNDIGVPLTLLRLTEAHQYAVIELGANHQGEIAWTTRLTRPESA
LVNNLAAAHLEGFGSLAGVAKAKGEIFLGLPENGTAIINLDSNDWPRWQTQLTQQRIWRF
SGTADAQADFYATDVAVNPQGTTFTLHTPQGALAVSLPLPGRHNIANALAASALALSVGA
PPEAIVQGLATLKAVPGRLFPITLAPQKLLLDDSYNANVGSMTAAAQVLGEMPGYRVMVT
GDMAELGAEAVECHREVGEAARKAGIDKVLSVGALSQHISDASGAGEHFSDKAALIARLQ
SLLAEHQIITVLVKGSRSAAMEQVVQNLQEKGTC
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgattacgctttctcttgaaacgctggcgcagattactcacggcacgttagtcggccag
ggggatatcgcgataagcgaagtgaccaccgacacccgtaaagtgacgccgggctgtttg
ttcattgcgttgcagggcgaacgctttgacgcacatgattttgccgaccaggcgatggcc
agcggcgcggcggcattattagtgagtaagcgcttgcaaatcaacgcgccgcaggtggtg
gtcagcgatacgcgcatcgccttaggagagctggcggcctgggtgcgtcagcaggtgaaa
acccgcgtagtggcgctgaccggctcctccggcaaaacttcggtaaaagagatgaccgcc
gctattctgcgtcagtgtggcgaaacgctttataccgccggtaacctgaacaacgatatc
ggcgtgccgttgacgctgctgcgcctgaccgaagcgcaccagtatgcggtcattgaactg
ggcgccaaccatcaaggtgaaatcgcctggaccacccgcttaacgcgcccggaaagcgcg
ctggtgaataacctggcagctgcgcatctggagggcttcggctcgctggcaggcgtggcg
aaagccaaaggcgaaattttcctcggcctgccggaaaacggcacggcgattattaacctc
gacagcaatgactggccgcgctggcagacgcagttgacccagcagcgcatctggcgcttc
tccggcaccgcggacgcgcaggctgatttttacgcgaccgatgttgcggtaaatccgcag
ggcaccacctttacgctgcatacgccgcagggggcgctggcggtctcgctgccgctgccg
ggtcgtcataacatcgccaacgcgctggccgccagcgctctggcgctctctgtcggcgcg
ccgccggaagcgatagttcagggcctggcgacgctgaaagcggtgccgggacgtctgttc
ccgataaccttagcgccgcagaagctgctgctggacgacagctacaacgcgaacgttggc
tcaatgaccgccgccgcgcaggtgctgggcgagatgccaggctaccgcgtaatggttacc
ggcgatatggcggagctgggcgcggaagcggtcgaatgccatcgcgaagtgggcgaggcc
gcgcgtaaggcgggcatagataaagtgctgagcgtgggcgcgctgagtcagcatatcagc
gacgccagtggcgcgggcgaacacttcagcgataaggccgccttgatcgcgcgcctccag
tcgctgcttgcagagcatcagattattaccgttttagttaaagggtctcgtagtgccgcc
atggagcaggtagtacaaaacttacaggagaaaggaacatgctag
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