Polistes canadensis: 106787111 Help Entry 106787111         CDS       T05611                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism pcf  Polistes canadensis Brite KEGG Orthology (KO) [BR:pcf00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:pcf04040]     106787111    04990 Domain-containing proteins not elsewhere classified [BR:pcf04990]     106787111 Ion channels [BR:pcf04040]  Voltage-gated cation channels   Ryanodine receptor    106787111 Domain-containing proteins not elsewhere classified [BR:pcf04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    106787111 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  106787111 NCBI-ProteinID:  XP_014604688 LinkDB All DBs Position Unknown AA seq 5160 aa AA seqDB search MADSEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETQQENLGKGTGSGHRTLLYGNAILLRHLNSDMYLA CLSTSSSNDKLAFDVGLQQHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTTKENDLSVVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTW STSPNQNIVTYEGGSVMSQARSLWRLELARTKWAGGFINWLHPMRIRHLTTGRYLAVKEN NELYLVDRNEATIETSTFWLRQEKDDQKIILEDKDLEVIGMPIIKYGDSTVIMQHSTTCL WVSYKSYETKKKGVGKVEEKQAVLHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTQF ITGLETLQINRRASMFFQNVNLNEMVMCLEDLINYFAQPEDDMEHEEKQNRFRALRNRQD LFQEEGILNLILEAIDKINVITSQGFLVALSGDESGQAWDQISGYLYQLLAAIIKGNHTN CAQFANSNRLNWLFSRLGSQASSEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEK HGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASIRPNIFVGR VEGSALYQKWYFEVTVDHIEQTTHMMPHLRIGWANTAGYMPYPGGGEKWGGNGVGDDLYS FGYDGANLWTGGRKTQVVQDATEPFIRKSDVIGCSLDLTVPVISFTFNGTHVAGSFRNFN LDGMFFPAISCSSKLSCRFLLGGDHGRLKYQPPEEFSPLVESLLPQQILSLDPCFYFGNM NKVVLAGPWLVEDDTAFVPAPVDTSMINLPSYVEQIRDKLAENIHEMWAMNKIEAGWIYG EHRDDLRKIHPCIVQFERLPAAEKRYDTQLAVQTLKTILALGYYITMDKPPSRIKTLRLP NEPFLQSSGYKPAPLDLSAINLTPKMEELVDQLAENTHNLWAKERISQGWTYGLNEDSEM RRSPHLVPYPKVDEAIKKANRDTASETVRTLLVYGYMLDPPTGEQHEALLLEANRLRQLY FRTYRVEKHYAVNSGKWYFEFEVLTAGPMRVGWAKADCMPGSMLGSDENTWAFDGYNEEK VYSGTAETFGKQWQVGDVVGVFLDLIDRTISFSLNGELLMDALGGETSFADVQGDSFVPA FTLGVGQKAKLTFGQDVNTLKFFTTCGLQEGYEPFCVNMNRLVTYWYTKDQPIFENTDDM ADTRIDVARIPAGSDTPPCLKISHNTFETMEKANWEFLRLSLPVICLSTFISENEKVRRW QDIKMHQSRLLSEQFEQTQQAAPSAQMEQIMKSGFSMSDIKGLQRNYSEDAVEADEMAKE SPIPMQRNKPMRPPRKGSIYGSRSGAMDSAVNEAEMNGYGEMNGDVKDDKKKRGRSPFRK LSKEMEDVFFSRKAKSPEAKAKTPELQVRSDVSDKSTRTLTASKTGSKTAQIRVSTTDLK VVPPQIPERNAPKIMSVLTGSGVEAIGNEIFDAECLKLMNEYFYGVRIFPGQDPTHVYIG WVTSQYHLHTKDFNLSRVRKASVVITDDYDRPVEQVDRQSCYMVRADELYNEVTQDASGK GASQGMFVGCFVDTATGCISFTCEGKETTHKFKMEPDTKLFPAIFVEATSKEILQIELGR TSTTLPLSAAVLQNSERHVIPQFPPRLKVQCLKPHQWARVPNQSLQVHALKLSDIRGWSM LCEDAISMLALHIPEEDRCIDILELIEMDKLLSFHAHTLTLYAALCYQSNYRAAHALCQH VDQKQLLYAIRAEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEFIIPLGQELKDLYED PEMKHSLRYLETESVRPQMKMTDIRRIPSSDQTIENIRSLYSPHFPLDVVRDYVMMALNE AVEVNQVHNRDPIGGSNENLFLPLIKLVDRLLLVGMLRNEDVVKLLIMINPETWDPTFDK EGKDEHKKGLLHMKMAEGAKLQMCYLLHHLNDIQLRHRVESIIAFSHDFVGDLQADQLRR YIDIKQSDLPSAVAAKKTREFRCPPREQMNAILSFKSLDPEEDSENCPCGEELVAKMNEF HNDLMSYVSLHALQEAADAANEPEEEIQKPGAMKKLFNFINAVKELEEEPKPEPEPEKKT PEEVFRKVLIATIVKWAEEAQIETPKLVREMFSLLVRQYDTVGELIRALEKTYVINSKTR EDVASMWVGLSQIRALLPVQMSQEEEELVRERLWKLVNNHTFFQHPDLIRVLRIHENVMA IMMNTLGRRAQAQSDAQTQAQAAEGEAASKEKDTSHEMVVACCRFLCYFCRTSRQNQKAM FDHFDFLLENSNILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAIYLSRCGL QSNSELVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPA LRGEGEGLLRAIIDANKMSERIADRRKLFKQVHDEAEGTAVVMQFEHPLPESDDDEDYID TGAAILNFYCTLVDLLGRCAPDSSVIEQESPSESLGKNESLRARAILRSLVPLDDLQGVL SLRFTLHNPAAGEERPKSDMPSGLIPGHKQSVVLFLERVYGIETQELFFKLLEEAFLPDL RAATMLDRNDGYESDMALAMNRYIGNSILPLLIKHSKFYNEADNYASLLDATLHTVYRLS KNRMLTKGQREAVSDFLVALTRCLDESNFSQMQPSMLLKLLRKLTVDVSKLSEYTTVALR LLTLHYDRCAKYYGSTGGQGAYGASSDEEKRLTMVLFSNIFDSLSKMDYDPELFGKALPC LTAIGCALPPDYSLSKNYEDEWYGSKSTSTQSPDGPYNPQPINTSSVVLNNDLNQIVQKF SEHYHDAWASRKLENGWTYGEQWSDVNKTHPRLKPYNMLNDYERERYKEPVRESLKALLA IGWSVEHAEVDVPSTNRSSMRRSSKSQGDSASPFNYNPHPVDMTNLTLSREMQNMAERLA DNAHDIWAKKKKEELVTCGGGIHPQLVPYDLLTDKEKRKDRERSQEFLKYLQYQGYKLHR PNRGGETEVASAGAAVELRFAYSLLEKLIAYLDKATINMKLLKPSDTFSRRNSFKTSTRD IKFFSKVVLPLMEKYFSTHRNYFIAVATATNNIGAASLKEKEMVAALFCKLANLLRSRLA AFGADVRITVRCLQVLVKGIDAKSLVKNCPEFIRTSMLTFFNNTADDLGHTILNLQEGKY SHLRGTHLKTSTSLSYINSVVLPVLTAMFDHLAACEYGSDLLLDEIQVASYKMLASLYTL GVDSSLTHDRKYLKTEIERHKPNLGSCLGAFSSCFPVAFLEPHLNKHNQYSLLNRIADHS LEAQDIMTKMESSMPTLETILTEVDQFVESEKTYNDAPHVVDVILPLLCSYLPFWWAQGP DNVNPTEGTYVSMVTSDHMNQLLKNVLKLIKKNIGNENAPWMTRIAAYTQQIIINSSEEL LKDPFLPLAERVRKRTDTMFHKEESLRGFIKSSTDDTSQVEAQIQEDWQLLVRDIYSFYP LLIKYVDLQRNHWLRNNIPEAEDLYNHVAAIFNIWSKSQYFLREEQNFISTNEIDNMVLI MPTATRRSTTVSDGTAPAGGGKKKKKHRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAG REQELVQHCKDRFLKKMPEYEIAEFAKTQLTLPDKIDPADEMSWQHYLYSKLGQKKDVME PVKAQQLEDVVARITDMAKVLYGLHMIDHPQQQSKSQYRSVVSIQRKRAVIACFRQTSLH SLPRHRAINIFARTYYELWLQDENVGQEVMIEDLTQSFEDAELKKMDKDEDEGKPDPLTQ LVTTFCRGAMTERSGALQEDPLYMSYAQIISKSCGEEEEEGEEEGGGGEEEGGASIHTWP HKLLMRPMHKLMEQEMEKQKLLFHQARLANRGVAEMVLLHISACKGVPSEMVMKTLELGI SILRGGNIEIQRGMLNHLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEG AAGEKNMHDAEFTCALFRFIQLTCEGHNLDWQNYLRTQAGNTTTVNVVICTVDYLLRLQE SIMDFYWHYSSKELIDPAGKANFFKAIGVASQVFNTLTEVIQGPCAQNQQALAHSRLWDA VGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTL VESAGNVELILKYFDMFLKLKDLVSSPSFLEVDLNSDGWVYPKDFKEKMEQQKSYTDEEI EFLLACCETNHDGKIDYVAFMDRFHEPAKEIGFNLAVLLTNLSEHMPNEPRLARFLETAG SVLNYFEPFLGRIEILGGNKKIERVYFEIKESNIEQWEKPQIKESKRTYFYNTVVEAGEK EKLETFINFCEDAIFEMQHASALMAVEESGGIGKARESSYTYMSEDDEERNKDPIRRGIQ AFKDGIYFFFSMFSPTNIKNKITEMQQMTIPELFIGFFKMIFYSFYYSGFGVGCVISYFM KLLLTLMRGPHMDEPAIEIKEEEEKPLRHLPALPPTPDESNLQVQAFGMDITKEEGGQIK IAPHESSTSTPQSSIEETGESTPDEGGGEEGIRTGDGGTGESDAPVKFVDLLGTGEQARA QAAAAAEAAAAQQAAMAAVEAEAKQETITEPSAASSIDFSEYTHRIVSFLARNFYNLKYV ALVLAFCINFMLLFYKVTSLAGDSDDEGSGDAMADILADMSGEGSSGSGGSGLEIGSGSG ENDSEEEEEDPMEFVEVSEDFYYMAHVMRLMAALHSIVSLAMLVAYYHLKVPLAIFKREK EIARRVEFDGLYIAESPEEDDIKAHWDKMVISAKTFPVNYWDKFVKKKVRQKYSETYDFD YISNLLGMEKTSFSQQEEEGSGLIHFIVNIDWRYQVWKAGVTITDNAFLYSLWYFTFSIL GNYNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIVVYIYTVIAFNFFRK FYIQEEDDEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGEPDGDDYEVYRIMFDITFFF FVIVILLAIIQGLIIDAFGELRDQLENVKTNMESNCFICGLGKEYFDTVPHGFDTHVQQE HNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRCWDFFPVGDCFRKQNEAVEEETKKK NT seq 15483 nt NT seq  +upstreamnt  +downstreamnt atggctgacagcgaaggtggctccgaacaggacgacgtatcattccttcgtacggaggat atggtatgtctgtcctgtacagcaacaggcgagagggtttgcctggcagccgaaggtttt ggcaatcgacattgtttcctcgaaaatatcgcagacaagaatattcctccagatctatcg caatgtgtgtttgtgatagaacaagctctctcggtgagagccctacaggaattagtcacg gctgctggctccgagacgcagcaagagaatttaggaaaaggtaccggatcaggacacaga actttactttatggcaatgccatacttttgaggcatctaaacagcgacatgtacctggca tgtctgtcaacgagttcatcaaacgataaactcgcatttgacgtaggtttacaacaacat tcacaaggcgaagcttgttggtggacagtacatccagcttcgaaacaaagatctgaaggt gaaaaggtccgagtaggtgacgatctaattcttgtatctgttgccactgaaagatacttg cacacaacgaaagaaaatgatttatcagtagtaaacgcatcgtttcacgtgacacattgg tcggtacaaccttatggtactggtataagtagaatgaaatacgtaggatacgtttttggt ggtgacgtattaagattttttcatggtggcgatgagtgtcttactataccttcgacatgg agcacgtcacctaatcaaaatatcgtaacatacgaaggaggaagtgttatgagtcaagca agatccttatggaggttggaattagctagaacaaaatgggcaggtggttttattaattgg ttgcatccaatgcgtataagacatttgacaactggtcgatatcttgcagtaaaagaaaat aatgaattatatttggtggacagaaacgaagcaacgatagaaacttcgacattctggctg agacaagagaaggatgatcaaaaaataatactcgaggataaagatttagaagttattgga atgccgattattaaatatggtgactcgacggttattatgcaacactctacaacgtgtctc tgggtttcttacaagtcgtacgagacaaaaaagaaaggcgtgggtaaggtggaagaaaaa caggcggtattgcacgaggagggaaaaatggacgatggtttggatttttcacgttcccaa gaagaagaatctagaacggcacgtgttattagaaaatgtagtagcttgttcacgcaattt attacaggtttagaaacgttgcaaattaatagaagagcatcgatgttttttcaaaatgta aatctcaatgaaatggtaatgtgtctggaagatttaatcaattatttcgctcagccagaa gatgatatggaacacgaagaaaaacaaaacagatttcgtgcgttaagaaatcgtcaagat ctgttccaagaagagggcatattaaatctcattttggaagcgatagataagattaacgtg atcacttcgcaaggttttcttgtcgcactttctggagacgaaagtggtcaagcgtgggat caaatttctggttatctttatcaattattagcagctataatcaaaggaaaccatacgaat tgcgctcaatttgcaaatagcaatcgtttgaattggttgttcagtcgtttaggttctcaa gcgtccagcgaaggtaccggaatgttggacgtacttcactgcgttcttattgattcgccc gaagctttgaacatgatgagggatgaacatatcaaagtgataatctctcttttggagaaa catggcagagatccaaaagttttggacgtgttgtgttccctttgcgtgggtaacggagta gctgtacgatcatcgcagaataatatatgtgattttttgcttcctggaaaaaatttactt cttcagacgcaactggttgatcacgtagctagcataagacctaacatatttgtcggtaga gtcgagggatcagcgttatatcagaaatggtatttcgaagttaccgtagatcatattgaa caaacaactcacatgatgccacatttgcggataggttgggctaacacagctggttacatg ccgtatccaggtggtggcgaaaaatggggtggaaacggtgtcggtgacgatctttactcg ttcggttacgatggcgcgaatctttggacaggtggtagaaagacacaagttgttcaagat gctacggaaccatttattagaaaaagcgacgtaattggttgttccttggatttgaccgtt cctgtaatatcgttcactttcaacggcactcacgttgctggctctttcagaaattttaat ctcgacggaatgtttttcccagcgatcagttgttcctccaaattatcctgtagatttctt ctcggtggcgatcatggaagattgaagtatcaaccacctgaggaattttcacctctggta gaaagtctactaccccaacagatactttccttggatccttgtttctattttgggaatatg aataaagttgtattagccggaccatggttggtggaagatgacacggcatttgttcctgca cctgttgatacttccatgatcaatctaccgagttacgtcgaacagataagagacaaacta gccgagaatattcacgaaatgtgggctatgaacaaaatcgaagctggatggatatacggt gaacacagagacgatttaagaaaaattcatccctgtatcgtacagtttgaaagattacct gccgctgaaaaacgatatgacactcaattagccgttcaaacgttgaagaccatattagct cttggatattacattacaatggacaaaccaccgtctagaataaaaacattaaggttacct aacgaaccattcttacaaagcagtggttataaaccggcacctctcgatctcagtgccatc aatttaacccctaaaatggaggaattggtggatcaattggcagaaaatacccacaatctt tgggcgaaagaacgaatcagtcaaggttggacttacggattgaacgaagattctgaaatg agaaggagtccgcatttggtaccgtatcctaaagtagatgaggccattaaaaaagctaat cgggatactgccagtgaaactgttaggacgcttctcgtctatggttatatgcttgatcca ccaactggtgaacaacacgaggctctattgttagaagctaatagattacgacaactgtat tttagaacgtatagggttgagaaacattatgcggttaacagtggcaaatggtatttcgaa ttcgaagttttaacagccggtcctatgcgcgttggttgggcaaaagctgactgtatgcca ggaagtatgttgggtagcgacgagaatacctgggcattcgatggctataacgaggaaaaa gtatactcgggcacagccgaaacattcggcaagcaatggcaggttggagatgttgtcggg gttttcctggatctaattgaccgaactattagtttttcattaaacggagaacttctgatg gatgcactcggtggtgaaacatcgttcgctgacgtacaaggtgattccttcgtaccagct tttacacttggcgtcggacaaaaggctaaactgacgtttggtcaggacgtgaatactttg aaatttttcactacttgcggtttgcaagaaggatacgaacccttttgcgtgaacatgaat cgtttagtcacgtattggtatacgaaggatcaaccaattttcgagaacaccgatgacatg gccgataccaggatagacgttgctagaattcctgcaggatcggacacaccgccctgttta aaaatttctcacaacacatttgaaactatggaaaaagctaattgggaatttttacgactt tcccttcccgttatttgcctgtcaacgtttatatcggaaaacgagaaggtacgaagatgg caggacattaaaatgcatcagagcagacttttgtccgaacaattcgaacaaacccaacag gcggcaccttcggctcaaatggaacaaatcatgaaatctggatttagcatgagcgatatc aaaggcttgcaaaggaattattctgaagatgctgtagaagctgatgagatggcaaaagaa tcaccaataccaatgcaaagaaataaacctatgagaccaccgagaaagggttcgatttat ggatcacgttccggagctatggatagtgctgtaaatgaagcagaaatgaacggttacggg gagatgaacggtgacgtcaaagatgataaaaagaaacgcggtcgttcgccgtttagaaag cttagcaaagaaatggaagatgtattcttttcgcggaaagcaaaatcaccggaggcaaaa gctaaaacgccggagcttcaagtacgttccgacgtatccgataaaagtacgaggacgctt actgcaagtaaaactggaagtaaaactgctcaaatacgtgtctctaccaccgacttgaaa gtagtcccaccacaaattccggaacgtaacgcacctaaaataatgtcggtattaactggc agtggggtggaagctatcggtaatgaaatctttgacgcggaatgtttaaaattaatgaac gaatatttctacggtgttagaatatttcccgggcaagatccgacacacgtatacattggt tgggtaacttcgcaatatcatttgcacacgaaggattttaatttgtcccgcgttaggaaa gcttcggttgtcattacagatgattacgatcgtccggtagaacaagtcgatagacaaagt tgttacatggtaagagccgatgaattatacaacgaagttacccaagatgcatcgggaaag ggtgcatcccaagggatgttcgtcggttgtttcgtggacaccgcaacgggttgcatttct ttcacctgcgagggtaaagaaaccactcacaaattcaaaatggaacctgacacgaaatta tttcctgcgatatttgtcgaagctaccagcaaagagatccttcaaatcgaacttggaaga acgtctacgacgttaccgttatctgcagcagttttacaaaattcagaacgtcatgtaatt ccacaatttcctcccagactcaaagtgcaatgtctgaaacctcatcaatgggccagagta ccaaatcaatcgcttcaggtccacgctttgaaattgtccgatatcagaggttggtcgatg ctttgcgaagatgcaatttcaatgttggctttacatattcctgaagaagataggtgtatc gatattctcgaactcattgaaatggacaaacttttaagtttccacgctcacacattgacg ctgtatgcggcattgtgttatcaatcgaactacagagcagctcatgcattatgtcaacac gtcgatcaaaaacaattattgtatgctatccgagccgaatatatgtccggaccattacga caaggtttttacgatttactgatcgcattacatctcgagtctcacgcaactacgatggaa gtttgcaaaaatgaatttatcatacctctaggtcaagaattgaaggatttgtacgaagat cccgaaatgaaacatagtcttagatatttggaaaccgaatccgtacggccgcaaatgaag atgactgatataaggcgaattccttctagcgatcaaactatcgagaatataagaagtcta tacagtccacactttcctctcgatgttgtacgtgattacgtgatgatggcattaaacgaa gccgttgaagtcaatcaggttcataatcgagatcctataggaggcagcaacgaaaattta ttcttgccattgataaaactcgtagatagattacttttggttggaatgcttagaaacgag gatgtcgtgaaattacttattatgatcaatccggaaacttgggatccaacatttgataaa gaaggcaaagatgagcacaaaaagggtttgcttcatatgaaaatggcggagggtgcaaag ttgcaaatgtgttaccttctccatcatttaaatgacattcaattacgtcatcgcgtagaa tctatcatagcgttcagtcatgatttcgttggtgatttgcaagccgatcaattgcgtcgt tacattgacatcaaacaatccgatttgccatctgccgtagctgccaaaaagacgagagaa tttcgttgtccgcctcgcgaacaaatgaatgcgatattaagtttcaaaagtctcgatccg gaagaagattcggaaaattgtccatgcggggaagaattagtggcaaagatgaacgaattt cacaacgatttaatgtcttacgtatcgttgcacgcattgcaagaagctgcggatgccgca aacgagcccgaggaagaaatacaaaaacccggtgctatgaagaaattatttaatttcatc aatgccgttaaggaactcgaggaagaaccaaaaccagaaccagaaccggaaaagaaaact cccgaggaagtatttcgtaaggttttaatagcaaccatagttaaatgggcggaagaagct cagattgaaacgcccaaactcgtacgtgaaatgtttagtttactcgtacgacaatacgac actgtaggcgaattgataagagcattggaaaaaacttatgtgattaatagtaaaactaga gaagacgttgcttcgatgtgggttggtttaagtcagattcgtgctttattgccagtacaa atgtctcaggaagaagaagaactcgtcagagagagattgtggaagttggtgaacaatcac acgttcttccagcatccagatttgattcgagtacttaggattcacgaaaatgtaatggcg attatgatgaatactttaggtagacgtgcacaggcacaatcagatgcacagacacaagca caggctgcagaaggagaagcagcttctaaagaaaaagatacatctcacgaaatggtagta gcttgttgtagattcctttgttatttctgtcgtacctcaaggcaaaatcaaaaggccatg ttcgatcattttgatttcctattggaaaacagtaacattctacttgccagaccatcattg agaggttctacaccattggatgtagcttattcctcattgatggaaaacactgaactggca ctcgcccttagagaacattatttagaaaaaatagcaatatatttgtcgagatgcggcctg caatcgaattccgaattggttgaaaaaggttatcctgatctcggttgggatccagtcgag ggtgaacgttatttagatttcttgagattttgtgtatgggtaaatggtgaaagtgttgaa gaaaatgcaaacttggtaatacgtttgttgataagaagaccggaatgtttgggtcctgca ttacgaggtgagggagaaggtttactgagagctataattgatgccaataagatgtccgaa cgtatcgccgatagacgaaaactttttaaacaggtgcacgacgaagccgagggtacagca gtggtgatgcagttcgagcatccgcttccagaatcagacgacgatgaagattacattgat acgggtgctgctattctcaatttttattgcaccctcgttgatttactcggtcgatgtgct ccagattcttccgtgatcgagcaagaatccccttcggaatcccttggaaaaaatgaatcg cttcgtgcaagagctattttacggtcgttggtaccattggatgatcttcaaggagtacta tcattaagatttacgttgcataatccagctgctggagaagaaaggccaaaaagtgatatg ccgtctggattgatacctggtcataaacaaagtgtcgtacttttcttggaacgcgtttat gggattgaaactcaagaattgtttttcaaattactcgaggaagctttcttaccagattta agagctgccaccatgttggataggaacgatggatacgaatccgacatggcccttgctatg aatcgatatataggaaacagtattttgccattattgataaaacattcaaagttttacaac gaggctgataattatgcgagtctattggatgctactttacataccgtatatcgacttagc aaaaatagaatgttaacgaagggtcaacgcgaagctgtctcagatttcctcgttgctttg accagatgtcttgacgagtctaatttttcccaaatgcaaccgagtatgttgcttaaatta cttcgaaaattaaccgtggatgtttcgaaattgtcagagtacaccacggtcgcattgagg ttgcttactttgcattacgatcggtgcgctaaatattacggatcgactggaggccaagga gcttatggtgcttcgagtgacgaagaaaaacgtttgacgatggttctgttcagtaatata ttcgattcgttgtctaaaatggattacgatccggaattatttggaaaagctttaccctgt ctcactgctattggttgtgctttaccaccggattattcattgtccaaaaattacgaagac gaatggtacggtagcaaatcaacgtctacccaatcacccgatggtccatataatccacaa cccatcaacacgtctagcgttgtactaaataacgatctgaatcaaatagtacaaaaattt tctgaacattatcacgatgcatgggctagtagaaaattagagaatggttggacttacggt gaacaatggtccgatgttaataaaactcatccaagattgaaaccttacaacatgttgaat gattacgagagagaacgttacaaagaaccagtcagagaaagtttaaaagctttattggct attggctggagtgtcgaacatgcagaagttgatgtaccatcgacgaatcgtagttctatg agaagatcatccaagagtcagggtgattctgcgagtccgtttaattacaatcctcatcca gttgacatgaccaatttgacgcttagcagagaaatgcaaaacatggccgaacgtttggcc gacaatgctcatgatatttgggctaagaaaaaaaaggaagaactcgttacgtgtggaggt ggtattcatcctcaattggtaccgtacgatcttttaaccgataaagaaaaacgaaaggat cgcgaacgttctcaagaattcttaaaatacttgcaatatcaaggttacaaacttcacaga ccaaatcgtggtggagaaacggaagttgccagtgccggtgcagcggttgaacttcgtttt gcttattccttattagaaaaattgatagcgtatctcgacaaagcgacgatcaacatgaaa cttttgaaaccatccgatacgtttagtcgtagaaacagtttcaaaacgtcgacgagggat atcaaatttttcagcaaagttgtattgccgttgatggaaaagtatttcagtactcatagg aattattttatcgcagtggcaactgctacgaataatatcggggcggcatcgttgaaggaa aaagaaatggtcgctgcattattctgcaaattggccaatttgttacgatcaaggcttgcc gcttttggtgctgacgtaaggataaccgttcgttgtctgcaggtccttgtaaagggtatc gacgcgaagagtttggttaaaaattgtcctgaatttatcaggacttctatgttgaccttt ttcaataatacagcagacgatttaggccatacgatattaaatcttcaagagggaaagtat agtcatcttagaggtacacatttgaaaacttcaacatcgttatcgtacatcaacagtgtc gtgttgccagttcttactgctatgtttgatcatctagctgcttgcgaatacggaagcgat ttgttacttgatgaaattcaagtagcctcttacaaaatgttggcatcactttatactctc ggtgtagattccagtttaactcatgatagaaaatacctgaaaactgaaatcgaacgtcac aaaccaaatcttggttcctgtttgggtgccttttcgagttgtttcccagttgccttttta gaacctcatttaaacaaacacaatcaatattcccttttaaatcgtatcgctgatcattca ttagaagctcaagacattatgacaaaaatggaatcaagtatgccaacattggaaacgatc ctaacggaagtcgatcaattcgttgagtctgaaaaaacttacaacgatgccccgcacgtt gttgacgtaatattaccacttttatgctcttacttaccattctggtgggcacaaggcccg gataatgttaatccaaccgaaggtacatacgtcagcatggtaaccagcgatcacatgaat caattattgaaaaatgtattaaaattgataaagaaaaatataggcaacgaaaatgcccca tggatgacacgaatcgctgcttatacgcaacagataattattaattcttccgaagaatta ctcaaagatccatttttacctttggccgaacgcgttagaaaacgtaccgataccatgttt cacaaagaagaatcccttcggggattcattaaatcttctactgatgatacatcgcaggtc gaagctcagatacaggaagattggcaacttttggtacgcgacatatattcgttttatcct cttcttattaagtacgttgatttacaaaggaatcattggttgagaaataatatacccgaa gctgaagatctttacaatcacgttgccgcgatattcaatatatggtcaaagtcacaatat ttcttacgcgaggaacaaaactttatatcgactaacgagattgataacatggttcttata atgccaactgcaactagaagatcaactaccgtttcggatggtactgctccggctggtggt ggaaagaaaaagaagaaacatcgtgacaaaaaaagagacaaggataaagaagttcaggcg tccctgatggttgcatgtctcaaacgtttgctaccagttggtttgaatctgttcgctggt cgtgaacaagaactcgttcaacactgcaaagatagattcttaaaaaagatgccggaatac gagatagccgaattcgctaagacccaattaacgttgcccgataaaatcgatcccgcggac gagatgtcctggcaacattatttgtattctaaattaggacagaagaaggatgttatggaa ccggttaaagctcaacaactcgaggacgtagttgctagaattacagacatggctaaagta ctgtacggcctacatatgatagatcatccacaacagcagagcaagagtcaataccgatca gtggtgtcgatacaacgcaaacgagcggtgatcgcttgtttccgtcaaacttccctacat tccttgcccaggcatcgggcaataaatatatttgcgaggacgtactacgaattatggttg caggacgaaaacgtaggtcaggaagtaatgattgaagaccttacgcaatcattcgaggat gcagaattgaaaaaaatggacaaggatgaagatgagggtaaaccagatccattaacacaa ctggtaacaacgttctgtcgtggtgcaatgactgaaagatccggtgctcttcaagaagat ccattgtacatgagttacgctcaaataatatctaaatcatgcggggaggaagaagaggag ggtgaagaggaagggggtggcggcgaagaagagggtggagcatccattcatacgtggcca cataaactgcttatgaggccaatgcacaaattaatggaacaagaaatggagaagcagaag ctgctttttcatcaagcacgtttagcgaatcggggtgtcgcggaaatggtattacttcat atatcagcgtgcaaaggtgttccaagcgagatggttatgaaaacattggaattgggaatt tctattcttcgcggtggtaacatagagatacaacgtggaatgttaaatcatctgaaggag aagaaggacgttggttttttcacctcgatcgcgggtcttatgaattcctgcagtgttctc gatttggatgctttcgagaggaatacaaaagccgagggtcttggtgttggttctgaaggt gctgctggtgaaaaaaacatgcacgatgctgaatttacgtgtgctttattccgttttata caattgacttgtgaaggtcacaatcttgattggcaaaattatctcagaacgcaagcgggt aatacaacaacggtaaacgtcgtcatatgtaccgtggattatttactacgattacaagaa tcaattatggatttttattggcattattcgagtaaagaattaattgatccggctggtaaa gcgaactttttcaaagcaatcggtgttgctagtcaagtattcaacacccttactgaagtt attcagggaccttgcgcacaaaatcaacaggctttagcacattcgagattgtgggatgcc gttggtggttttctatttttgttttcacacatgcaagataaattatcgaaacactccagt caagtagatcttttgaaagaattattgaatctacaaaaggatatgatcactatgatgcta tcaatgttggaaggaaacgtcgttaatggtactatcggaaaacagatggttgacacgttg gtcgagtcagcgggtaacgtcgaattaattctaaaatatttcgatatgtttctgaaatta aaagatctagtatcatcgcccagtttcttagaagtagatcttaatagcgacggttgggta tatcctaaagattttaaagagaaaatggaacaacaaaaaagttacaccgacgaagagata gaatttttattggcttgctgcgagactaatcacgacggtaaaatcgattacgttgccttc atggatcgtttccacgaaccagcgaaagaaattggttttaatctcgctgtacttttgact aatctttctgagcatatgccaaacgagcctagattggctagattcctcgaaactgctggc tcagttttaaattatttcgaaccatttttaggaaggatagaaattttaggtggtaataaa aaaatcgaacgggtatatttcgaaatcaaagaatcaaacatagaacagtgggaaaagcca cagataaaagaatcaaaaagaacgtatttctataacacggtagtcgaggcaggtgaaaaa gaaaaattagaaactttcattaatttttgcgaagatgcgatatttgaaatgcaacatgcc agtgctttgatggcggtagaagagagcggtggtattggtaaagcgagagaatcatcttac acttacatgtcggaagacgacgaagaaagaaacaaagatccgataaggagaggtatacaa gcattcaaggatggcatttatttcttcttttcaatgttctcaccgacaaatataaaaaac aaaataacggagatgcaacaaatgacgatacccgaattatttattggctttttcaaaatg atattttattcgttttattattccggatttggtgttggttgcgtgataagttactttatg aaattattattaactttgatgagaggaccacatatggatgaacccgctattgagataaaa gaagaagaagaaaaaccattgagacatttgcctgctttacctccaacgccggatgaatct aatttacaggtacaagctttcggaatggatataacgaaagaggaaggtggtcaaataaaa atagcaccacacgaatcgtcgacttcaacaccacaatcaagtatcgaggaaactggtgaa agtactccggacgagggtggcggtgaggaaggtataaggacaggtgatggaggtactgga gaatctgatgcacctgttaaattcgtcgatttacttggtaccggcgaacaagcaagggcc caagccgcagcagcagctgaagcggcagctgctcaacaagcagcaatggcagctgtggaa gctgaagcaaaacaagaaacaataaccgaaccgtcggctgcatcgtcaattgatttttcg gaatacactcatcgcattgtctcatttttggctagaaacttttataatcttaaatacgtt gcccttgttcttgccttttgtataaatttcatgctactattctacaaggtcacatctcta gctggggattccgacgatgaaggtagtggggatgccatggctgatatattagctgacatg tcgggagaaggttcatctggttcaggaggtagcggtttagaaattggaagtggtagcggt gaaaatgattccgaagaggaagaggaagatcctatggaattcgttgaagtttcggaagat ttttattatatggcacacgttatgaggctaatggctgcattacattctatcgtttcttta gccatgcttgtagcatattatcatcttaaagtaccgttagccatattcaaacgtgaaaaa gaaattgcccgtcgtgtcgagttcgatggtttgtacattgccgaaagtcccgaggaggat gacatcaaagcacattgggataaaatggtaatatcggctaaaacgtttcccgttaattat tgggacaaattcgtcaaaaagaaagttagacaaaagtatagcgaaacgtacgatttcgat tacatcagtaatttgctcggcatggaaaagacatctttcagtcaacaagaggaagaaggt tctggtttgatacattttatcgtaaatatcgattggagatatcaagtatggaaagctggt gtcactatcacagataatgcatttctatacagtctctggtacttcacattttcgattttg ggaaattacaataactttttctttgctgcccatctgctcgacgttgcggttggtttcaaa acattgagaactatcttacagtccgtaacgcacaacggaaaacaattggtgctaacagta atgttgttaacaatcgtagtatacatttataccgtgatagccttcaatttctttagaaaa ttttatattcaagaggaagacgacgaagttgacaaaaagtgtcacgacatgttaacgtgt ttcgtttttcacttatacaaaggtgtaagagccggtggtggtatcggtgacgaaatcggg gaaccagatggcgatgattatgaagtttatcgtatcatgtttgacattacattctttttc ttcgtcatcgttattcttctcgctattattcaaggtttaatcatcgacgcttttggtgaa cttcgtgaccagctggaaaacgtcaaaacgaatatggaaagcaattgtttcatatgtggt ttaggaaaagaatattttgacacggtaccacacggatttgacacccacgttcaacaagaa cacaatctagctaattatatgttcttcctgatgcatctaatcaacaaaccagatacagaa tacacgggtcaagaaacttacgtttggaatatgtaccaacaaagatgttgggatttcttc cctgtcggtgattgcttccgtaaacagaacgaagcggtagaagaggaaactaagaagaaa taa

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