Proteus terrae subsp. cibarius: F9282_02830
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Entry
F9282_02830 CDS
T06330
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pcib
Proteus terrae subsp. cibarius
Pathway
pcib00260
Glycine, serine and threonine metabolism
pcib00261
Monobactam biosynthesis
pcib00270
Cysteine and methionine metabolism
pcib00300
Lysine biosynthesis
pcib01100
Metabolic pathways
pcib01110
Biosynthesis of secondary metabolites
pcib01120
Microbial metabolism in diverse environments
pcib01230
Biosynthesis of amino acids
Module
pcib_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pcib_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
pcib_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
pcib_M00526
Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
pcib00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
F9282_02830 (thrA)
00270 Cysteine and methionine metabolism
F9282_02830 (thrA)
00300 Lysine biosynthesis
F9282_02830 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
F9282_02830 (thrA)
Enzymes [BR:
pcib01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
F9282_02830 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
F9282_02830 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QGW01982
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All DBs
Position
586659..589118
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AA seq
819 aa
AA seq
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MRVLKFGGTSVANAERVLNVADIAEKKREQGQVALVLSAPAKITNYLVAMIEKTAEGEDP
LTQVREAEQIFANLLQGLREKQPGFDYERLKDKVEREFAEIKHILHGISLLGQCPDSINA
AMICRGEKLSIAIMESVLQARGYNVTVIDPVKNLLAQGHYLESTVDIPESTRRILELNIA
KDDMILMAGFTAGNEKNELVVLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYTCDPRLV
PDARLLKGMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPDAPGTLIGDGQK
DDSTPVKGITNLNNMAMINVSGPGMKGMVGMAARVFSVMSRAGISVVLITQSSSEYSISF
CVPQKELIRAQKALSDEFYLELKDGVLDPLDIMENVAIISVVGDGMRTLKGISARFFSAL
TRGNINIVAIAQGSSERSISAVIANDSATNAVRLCHQMLFNTNQIVEVFIVGVGGVGSAL
IEQIHRQQAWLKNKHIDLRVCGIANSRAMLTDMQGIDLDNWQQALKEAKEPFSFSQLIRL
EKEYHFLNPVIVDCTSNEEIAQQYANFLQNGFNVVTPNKKANTLSMDYYYQIRQAAEASR
RKFLYDTNVGAGLPVIENLQNLLNAGDELVQFNGILSGSLSYIFGQLDEGKSLSEATFSA
KDKGFTEPDPRDDLSGMDVARKLLILAREAGYKLELSDIDVEPVLPASFDSSGDVASFLN
RLPQVDVEFDAKVEEAQKAGKVLRYVGIINEGKCQVKIMAVDANDPLFKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADVLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttaaaatttggaggaacttcagttgccaacgccgagcgtgtgctgaatgtt
gctgatatcgctgagaaaaaaagagagcagggacaagtcgctctcgtattatcagcacca
gccaagataactaactacttggttgcaatgattgaaaaaacggcagaaggcgaagatcct
ctcactcaagtacgagaagccgagcaaatttttgccaacttattacaaggtctaagagaa
aaacagccaggtttcgattatgaacgcttaaaagataaggttgagcgtgaatttgcagag
atcaaacatattcttcatgggatctctttattaggccaatgccctgatagcatcaatgca
gcgatgatttgtcgtggtgaaaagctgtctatcgccattatggaatctgttttacaggct
cgaggctacaatgtcactgtaatcgatccagtcaaaaatttgctcgcacaaggtcattat
ttagaatctactgttgatattcctgaatctactcgtcgcatcttagaactcaatatcgca
aaagacgatatgattttaatggcaggttttactgcgggtaatgagaaaaatgaactcgtg
gtattaggccgtaatggttcagactactccgctgctgtattagctgcttgcttacgtgca
gagtgttgtgaaatttggacggatgttgacggtgtttatacttgcgatcctcgtttagtt
cctgatgcacgcctgttaaaaggcatgtcatatcaagaagcgatggaactctcttacttt
ggtgctaaagtacttcaccctcgtacaattgcacctattgcccaattccaaattccttgt
ttaataaaaaacacaggcaatccagatgctccgggtacattaattggtgatggtcaaaaa
gacgatagtacccccgttaaagggatcactaaccttaataatatggcgatgatcaacgta
tctggccccggaatgaaaggtatggtggggatggctgctcgtgtattctctgttatgtcg
agagcgggtatttctgttgtcctgattacgcaatcttcttctgaatacagcatcagcttt
tgtgtgccacaaaaagaacttattagagcgcaaaaagcattatcagatgaattttattta
gaattaaaagatggtgtactagatccattagatatcatggaaaacgtcgctatcatctct
gttgtcggtgatggtatgcgtactttaaaagggatttcagcgcgtttcttctctgcatta
actcgtggcaatattaatattgtagctattgcacaaggttcttccgaacgttcaatttca
gccgttatcgctaatgattcagcaaccaatgctgtgcgcttgtgccatcaaatgcttttc
aacaccaatcaaattgttgaagtctttattgttggtgttggtggtgtcggtagcgcgtta
attgaacagatccatcgccaacaagcatggttgaaaaataagcatatcgatcttcgtgta
tgtggcattgctaactcaagagccatgctgacagatatgcaaggtattgatttagataat
tggcaacaggctttaaaagaagccaaagagccatttagctttagccaacttattcgttta
gaaaaagagtaccacttcttaaatccagtgatcgttgattgcacatcaaacgaagaaatt
gcgcaacaatacgcaaatttcttacaaaatggctttaacgtggttacaccaaacaaaaaa
gcgaatacgctgtcgatggattattactatcaaattagacaagcagcggaagcttcacgc
cgtaaattcttatatgacactaacgtaggtgcaggtttgcctgttattgagaacttgcaa
aacttgctaaacgcaggcgatgagttagttcaatttaatggtattctttcaggatcatta
tcttacatttttggtcaattagatgaaggtaaaagcttatctgaagcgactttttcagca
aaagataaaggttttactgagccagatcctcgtgatgacctttcaggtatggatgttgcg
cgtaaactgcttattttagcgcgtgaagcgggttataaattagaattaagtgatatcgat
gtagagcctgtactgcctgcttcatttgatagctctggtgatgtagcaagcttcttaaat
cgtttacctcaagttgatgttgaatttgatgctaaagtcgaagaagcacaaaaagcaggt
aaggtattacgttatgttggcattatcaatgaaggtaaatgccaagttaagataatggca
gttgatgcaaatgatcctctgtttaaagtgaaaaatggtgaaaatgctttagccttttac
actcgctactatcaacctattccattggtattacgtggatatggtgctggtaatgatgtt
actgctgctggggtgtttgcagatgtattacgtaccttatcatggaaattgggagtttaa
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