Pseudophryne corroboree (corroboree frog): 134909631
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Entry
134909631 CDS
T11513
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pcob Pseudophryne corroboree (corroboree frog)
Pathway
pcob00270
Cysteine and methionine metabolism
pcob00480
Glutathione metabolism
pcob01100
Metabolic pathways
pcob01240
Biosynthesis of cofactors
pcob04216
Ferroptosis
Brite
KEGG Orthology (KO) [BR:
pcob00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
134909631 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
134909631 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
134909631 (GCLC)
Enzymes [BR:
pcob01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
134909631 (GCLC)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
Imm44
Motif
Other DBs
NCBI-GeneID:
134909631
NCBI-ProteinID:
XP_063772779
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All DBs
Position
4:complement(389503044..389700188)
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AA seq
638 aa
AA seq
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MGLLSHGSPLSWEETKKYADHVRQHGILQFLHIYNKVKERQKDVLKWGDEVEYILIAFDH
ENQKVRLVLKGEEMLDTLQDRGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMAEFNTV
EDNMKKRRLEASSLLAENHSICTITSFPRLGCPGFTLPEFPPTPVEQGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVDINVPIFKDQNTPSPFIERFVNDSGNEAKALKPDHIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAAAPFYRGYVSDIDCRWGV
ISASVDDRTKEERGLQPLKNDKYRISKSRYDSIDSYLSTCGEKYNDIDLTIDKEIYNQLT
REGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDTNESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGLFYFRKDISKAGIAGCCTALNGTESETEEYTLMSIDTIINGKEGIFPGLLPILNSYL
ENMEVDVDTRCTILNYLKLIKKRASGELMTAARWMREFVSNHPDYKQDSVITDKINYDLM
VKCNQIANEKVNCPELLGFTTTKVKQSGFKPVSGGLHS
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atgggtctgctgtctcacggctccccactcagctgggaagagacgaagaagtacgcggac
cacgtccggcagcacggcatcctccagttcctgcacatctacaacaaggtgaaggagcgc
cagaaggacgtgctgaagtggggcgacgaggtggagtacatattgattgccttcgatcat
gaaaatcaaaaagtgcgtttagtgcttaaaggagaagaaatgcttgatacgcttcaagac
agaggtgaaaaaataaaccctaaccatccaacactttggagaccagagtatggtagttat
atgattgaaggtacacctggacagccttatggtggaacaatggcagagtttaacactgtg
gaagacaatatgaagaaaaggcgtctggaagcttcatcattgcttgcagaaaatcattca
atttgcactataacatcctttccaagattgggatgtcctggattcacgttgccagagttt
ccaccaactccagtggagcaaggagcctccaagtccctcttttttccagatgaagcaatt
aacaaacatccccggtttagtactttgaccagaaatattaggcacagacgtggtgaaaaa
gttgatattaatgttccaatttttaaagatcaaaatacaccctctccatttattgaaaga
tttgtgaatgatagtggtaatgaagccaaggcattgaagcctgatcatatttacatggat
gccatgggatttggcatgggcaactgctgtcttcaggtcactttccaggcttgcagcatt
tcagaagccaggtatctatatgaccagctagctacgatatgtccaattgtgatggctttg
agtgctgctgcccctttctacaggggatatgtgtctgacattgattgccggtggggagta
atttctgcctctgtagatgatcgaactaaagaagaaagaggtctgcagcctctgaagaat
gacaagtaccgaatcagtaaatctcggtatgattctatagatagttatctatctacgtgt
ggtgaaaagtacaatgatattgatttgactatagacaaagagatctataaccagctaacg
agagagggaattgaccatctcttggctcagcacattgcccatctctttatcagagatcct
ttgacattgtttgaagagaaaatacatttggatgataccaatgaatctgaccattttgag
aatattcaatcaacaaattggcaaaccatgaggtttaagcctcctccacccaattctgat
atagggtggagagtagaatttcgacctatggaggtccagttaacagactttgaaaactcc
gcctatgtagtgtttgttgtgttactgaccagagtaattctttcttacaagctggatttt
ctcattcctttgtcaaaggttgatgaaaacatgaaagttgcccagaaacgagatgctgtg
cgtcagggattgttttatttcagaaaggatatttctaaagctggcattgctggatgttgt
actgctcttaatggtacagaatctgaaactgaagagtacaccctcatgagcattgataca
ataatcaatggaaaggagggtatttttccaggtttacttccaatacttaattcatacctt
gaaaacatggaggtagatgtggacactcgctgcaccattttaaactaccttaaattaatc
aagaaaagagcttctggagaactgatgacagctgctcgatggatgagggaatttgtttca
aaccatccagactacaagcaagacagtgtgatcacagacaaaattaattatgacctcatg
gtaaaatgcaaccaaatagcgaatgaaaaggttaactgtccggagttgcttggctttacc
actactaaagtaaagcaaagcgggttcaaacctgtctctggtgggctacacagctag
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