KEGG   Phasianus colchicus (Ring-necked pheasant): 116225470
Entry
116225470         CDS       T07365                                 
Symbol
MAP2K1
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 1
  KO
K04368  mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
Organism
pcoc  Phasianus colchicus (Ring-necked pheasant)
Pathway
pcoc04010  MAPK signaling pathway
pcoc04012  ErbB signaling pathway
pcoc04068  FoxO signaling pathway
pcoc04114  Oocyte meiosis
pcoc04140  Autophagy - animal
pcoc04148  Efferocytosis
pcoc04150  mTOR signaling pathway
pcoc04210  Apoptosis
pcoc04218  Cellular senescence
pcoc04270  Vascular smooth muscle contraction
pcoc04370  VEGF signaling pathway
pcoc04371  Apelin signaling pathway
pcoc04510  Focal adhesion
pcoc04540  Gap junction
pcoc04620  Toll-like receptor signaling pathway
pcoc04810  Regulation of actin cytoskeleton
pcoc04910  Insulin signaling pathway
pcoc04912  GnRH signaling pathway
pcoc04914  Progesterone-mediated oocyte maturation
pcoc04916  Melanogenesis
pcoc05132  Salmonella infection
pcoc05164  Influenza A
Brite
KEGG Orthology (KO) [BR:pcoc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116225470 (MAP2K1)
   04012 ErbB signaling pathway
    116225470 (MAP2K1)
   04370 VEGF signaling pathway
    116225470 (MAP2K1)
   04371 Apelin signaling pathway
    116225470 (MAP2K1)
   04068 FoxO signaling pathway
    116225470 (MAP2K1)
   04150 mTOR signaling pathway
    116225470 (MAP2K1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116225470 (MAP2K1)
   04148 Efferocytosis
    116225470 (MAP2K1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    116225470 (MAP2K1)
   04210 Apoptosis
    116225470 (MAP2K1)
   04218 Cellular senescence
    116225470 (MAP2K1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    116225470 (MAP2K1)
   04540 Gap junction
    116225470 (MAP2K1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116225470 (MAP2K1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    116225470 (MAP2K1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116225470 (MAP2K1)
   04912 GnRH signaling pathway
    116225470 (MAP2K1)
   04914 Progesterone-mediated oocyte maturation
    116225470 (MAP2K1)
   04916 Melanogenesis
    116225470 (MAP2K1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    116225470 (MAP2K1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    116225470 (MAP2K1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116225470 (MAP2K1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcoc01001]
    116225470 (MAP2K1)
Enzymes [BR:pcoc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     116225470 (MAP2K1)
Protein kinases [BR:pcoc01001]
 Serine/threonine kinases: STE group
  STE7 family
   116225470 (MAP2K1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7
Other DBs
NCBI-GeneID: 116225470
NCBI-ProteinID: XP_031443724
Ensembl: ENSPCLG00000005380
UniProt: A0A669PJ80
LinkDB
Position
Unknown
AA seq 395 aa
MPKKKPGPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
GELKDDDFEKISELGAGNGGVVFKVSHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHE
CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
SVQSDIWSMGLSLVEMAIGRYPIPPPDSKELELMFGCPVEGDSPVTETSPRQRTPGRPMS
SYGPDSRPPMAIFELLDYIVNEPPPKLPNGVFGSEFQDFVNKCLIKNPAERADLKQLMIH
AFIKRSEAEEVDFAGWLCSTIGLNQPSTPTHAAGV
NT seq 1188 nt   +upstreamnt  +downstreamnt
atgcccaagaagaagccggggccgatccagctcaaccccgctccggatggctccgccgtc
aacgggaccagctctgccgagacaaacttggaagcgcttcagaagaagctggaagagcta
gagttggatgaacagcaacggaaacgccttgaagctttccttacccagaaacaaaaagtt
ggggagctgaaggatgacgactttgagaagatcagtgagctgggagcagggaatggtggg
gtggtgttcaaagtatctcacaagccttctggcctcatcatggcaagaaagttgattcat
ctagagatcaagccagctattcgaaaccagatcatccgtgagctgcaggttctacatgag
tgcaattcaccatacatagtgggcttttatggagctttttacagcgatggggaaatcagc
atttgcatggaacacatggatggtggctcattggatcaagtgttgaaaaaggctggaaga
attccagagcagatactgggcaaagtcagcattgcagtaataaaaggactcacgtatctg
agagaaaagcataaaataatgcacagagatgttaaaccatctaacattttggtaaactct
agaggtgagatcaagctttgtgactttggtgtcagtggacaactgatagattctatggca
aactcgtttgtcggcacgcgctcctacatgtctccggaaaggctgcagggaactcattat
tcagtgcagtcggatatatggagtatggggctgtctctggtagaaatggccattggcaga
taccccattcctcctcctgactctaaagagctcgagttgatgtttggctgcccggtagag
ggagattctccagtcacagagacctcacccaggcaaagaacacctggtcgaccaatgagc
tcctatggaccagacagcagacccccaatggcgatctttgaacttctggattatatcgtc
aatgagccacctccgaaactgcccaatggtgtttttggttctgaatttcaagattttgtt
aacaaatgtttaattaaaaatcctgctgagagagctgatttgaagcagctgatgattcat
gctttcataaagagatctgaagcagaggaggtggattttgcaggatggctttgctcaacc
ataggccttaaccagccaagtacacccacgcatgctgctggagtctga

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