Proteus columbae: F1325_02945
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Entry
F1325_02945 CDS
T06419
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pcol
Proteus columbae
Pathway
pcol00260
Glycine, serine and threonine metabolism
pcol00261
Monobactam biosynthesis
pcol00270
Cysteine and methionine metabolism
pcol00300
Lysine biosynthesis
pcol01100
Metabolic pathways
pcol01110
Biosynthesis of secondary metabolites
pcol01120
Microbial metabolism in diverse environments
pcol01230
Biosynthesis of amino acids
Module
pcol_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pcol_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
pcol_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
pcol_M00526
Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
pcol00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
F1325_02945 (thrA)
00270 Cysteine and methionine metabolism
F1325_02945 (thrA)
00300 Lysine biosynthesis
F1325_02945 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
F1325_02945 (thrA)
Enzymes [BR:
pcol01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
F1325_02945 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
F1325_02945 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QHN09477
UniProt:
A0A6I7D9W8
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All DBs
Position
608118..610577
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AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANAERVLNVADIAEKKREQGQVALVLSAPAKITNYLVAMIEKTAEGEDP
LTQVREAEQIFANLLQGLREKQPGFDYERLKDKVEREFAEIKHILHGISLLGQCPDSINA
AMICRGEKLSIAIMGSVLQARGYNVTVIDPVKNLLAQGHYLESTVDIPESTRRILELNIA
KDDMILMAGFTAGNEKNELVVLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYTCDPRLV
PDARLLKGMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPDAPGTLIGDGQK
DDSTPVKGITNLNNMAMINVSGPGMKGMVGMAARVFSVMSRAGISVVLITQSSSEYSISF
CVPQKELMRAQKALSDEFYLELKDGVLDPLDIMENVAIISVVGDGMRTLKGISARFFSAL
TRGNINIVAIAQGSSERSISAVIANDSATNAVRLCHQMLFNTNQIVEVFIVGVGGVGNAL
IEQIHRQQAWLKNKHIDLRVCGIANSRAMLTDMQGIDLDNWQQELKEAKEPFSFSQLIRL
EKEYHFLNPVIVDCTSNEEIAQQYANFLQNGFNVVTPNKKANTLSMDYYYQIRQAAEASR
RKFLYDTNVGAGLPVIENLQNLLNAGDELVQFNGILSGSLSYIFGQLDEGKSLSEATLSA
KDKGFTEPDPRDDLSGMDVARKLLILAREAGYKLELSDIDVEPVLPVSFDSSGDVASFLN
RLPQVDVEFDAKVEEAQKAGKVLRYVGIINEGKCQVKIMAVDANDPLFKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADVLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttaaaatttgggggaacttcagttgccaacgcagagcgtgtgctgaatgtt
gctgatatcgctgagaaaaaaagagagcaaggacaagtcgctcttgtattatcagcacca
gccaagataactaactacttggttgcaatgattgaaaaaacggcagaaggcgaagatcct
ctcactcaagtacgagaagccgagcaaatttttgccaacttattacaaggtttaagagaa
aaacaacctggttttgactatgagcgcttaaaagataaagttgagcgtgaatttgcagag
atcaaacatattcttcatgggatctctttactaggtcaatgccctgatagcatcaatgca
gcgatgatttgtcgtggtgaaaagctttctatcgctataatgggatccgttttgcaggct
cgtggctataatgtcactgtgatcgatccagtcaaaaatttactcgcacaaggtcattac
ttagaatcgacagttgatattcctgagtctactcgccgcatcttagaactcaatatcgca
aaagacgatatgattttaatggcaggctttactgcgggtaatgaaaagaatgaactcgtg
gtattaggtcgtaatggctcagactactctgctgctgtgttagccgcttgcttacgtgca
gagtgttgtgaaatttggactgatgttgacggtgtttatacttgtgatcctcgtttagtt
cctgatgcacgtctgttaaaaggcatgtcttatcaagaagcgatggaactctcttacttc
ggcgctaaagtacttcatcctcgcactattgctccaatcgcccaattccaaattccttgt
ttaataaaaaacactggcaacccagatgcgccgggtacattaattggtgatggtcaaaaa
gatgatagtacaccagttaaagggatcaccaaccttaataatatggcgatgatcaacgta
tcaggccctggtatgaaaggtatggtggggatggccgctcgagtgttctctgttatgtca
agagcgggtatttctgttgttctgattacacaatcttcttctgaatacagcatcagcttt
tgtgtaccgcaaaaagaacttatgagagcgcaaaaagccttatcagatgaattttattta
gaattaaaagatggtgtacttgatccattagatatcatggaaaacgtcgctatcatctcc
gttgtaggtgatggtatgcgtactttaaaagggatatcagcgcgtttcttctctgcttta
acccgtggcaatattaatatcgttgcgatagctcaaggctcttcagagcgttctatttct
gccgttattgcgaatgattctgcaactaacgcggtgcgtttatgccatcaaatgcttttc
aacactaatcaaattgttgaagtctttattgtcggtgttggtggtgttggcaacgcatta
attgaacaaatccatcgccagcaagcatggttgaaaaataagcatatcgatcttcgtgtc
tgtggtattgctaactcaagagccatgctgacagatatgcaaggtattgatttagataat
tggcaacaagaacttaaagaagccaaagaaccttttagctttagtcagcttattcgttta
gaaaaagagtaccacttcttaaatccagtgatcgttgattgcacatcaaacgaagaaatt
gcgcaacaatacgcaaatttcttacaaaatggctttaacgtggttacaccaaacaaaaaa
gcgaatacgctgtcgatggactattactaccaaattcgacaagcagcggaagcttcacgc
cgtaagttcttgtatgacactaacgttggtgcaggtttaccggttattgaaaacttacaa
aacttgctcaatgcgggcgatgagttagttcaatttaatggtattctttcaggctccttg
tcatacatttttggtcaactagatgaaggtaaaagcttatctgaagcgactctttcagca
aaagataaaggttttacagagcctgatcctcgtgatgatctttctggtatggatgttgcg
cgtaaactgcttattttagcgcgtgaagcgggttataaattagaactcagtgatatcgat
gtagagcctgtgctgcctgtttcatttgatagctcaggtgatgtagcaagcttcttaaac
cgtttacctcaagttgatgttgaatttgatgcaaaagtcgaagaagcacaaaaagcaggt
aaggtattacgttatgttggcatcatcaatgaaggaaaatgccaagttaagataatggca
gttgatgcaaatgatcctctgtttaaagtgaaaaatggtgaaaatgctttagccttttac
actcgctactatcaacctattccattggtattacgtggatatggtgctggtaatgatgtt
actgctgctggggtgtttgcagatgtattacgtaccttatcatggaaattgggagtttaa
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