Puma concolor (puma): 112850227
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Entry
112850227 CDS
T08890
Symbol
FPGS
Name
(RefSeq) LOW QUALITY PROTEIN: folylpolyglutamate synthase, mitochondrial
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00790
Folate biosynthesis
pcoo01100
Metabolic pathways
pcoo01240
Biosynthesis of cofactors
pcoo01523
Antifolate resistance
pcoo04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
112850227 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
112850227 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112850227 (FPGS)
Enzymes [BR:
pcoo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
112850227 (FPGS)
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Paralog
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Motif
Pfam:
Mur_ligase_M
Motif
Other DBs
NCBI-GeneID:
112850227
NCBI-ProteinID:
XP_025769639
UniProt:
A0A6P6H1S4
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Position
Unknown
AA seq
509 aa
AA seq
DB search
MGCGKPRDERYQVPGCLXNRWLRRRACKQPMEQPGPSGSLFSANTASFQDAVRALNTLQT
NAGYLEQVKRQRGDPQAQLEAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERI
LRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWPLYHRLEETKDSSSYVSMPA
YFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGISSLGIDHTSILGDTV
EEIAWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLG
LEGEHQRSNAALALQLARCWLQQKDYRGIGELKVSRPSLLRQMPLAPVFQPTTHMRHGPG
MRVQGLALSRCTQQVSPVAHTDQQNFMVTLDQVLLRCLAHQQHWSRLDEEQAGPEPGEPT
SLLLAPHPPEPRSTSSLVFSCISHALLWISQGRDPVFQPPSPPQGLFAHPVAGSGAGVLR
EAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atggggtgtgggaagcccagggatgaaaggtaccaggtccctggctgcctcnctaaccgg
tggctgagaaggcgtgcttgcaagcaaccaatggagcagccgggcccatcggggagtctc
ttctcagctaacactgcctcctttcaggatgctgtgcgcgcactgaacaccctgcagacc
aatgctggctatctggagcaggtgaagcgccagcggggtgaccctcaggcacagctggaa
gccatgaagctgtacttggcacggagtgggctgcaggtggaagacttggaccagctgaac
atcattcacgtcactgggaccaaggggaagggttccacttgtgcctttactgaacgtatt
ctccgaagctatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgg
gagcggatccgcatcaacgggcagcccataagccctgagctcttcaccaagcacttctgg
cccctctaccaccggctggaggagaccaaggacagcagcagctatgtctccatgcccgcc
tacttccgcttcctcacgctcatggccttccatgtcttcctccaagagaaggtggacctg
gcagtggtggaggtgggcattggtggtgcttacgactgcaccaacatcatcaggaagcct
gtggtgtgtggcatttcctctcttggcatcgaccacaccagcattctgggggacacagtg
gaggagatcgcgtggcagaaagggggcatcttcaagcgtggcgtccccgccttcaccgtg
ctccagcctgacggtcccctggcagtgctgagggaccgggcccagcagatctcatgtcct
ctctacctgtgcccaccactggaagccctggaggaaggggggccgccgctgaccctgggc
ctggagggagagcaccagcggtccaatgccgccttggccttgcagctggctcgctgctgg
ctacagcaaaaggactaccggggcatcggggagctgaaggtgtccaggcccagtctcttg
cggcagatgcccctggcgcccgtgttccagcccacgacccacatgcggcatggacccggg
atgcgtgtacagggcctggcgttaagcaggtgcacacagcaggtgtcccctgtcgcccat
acagaccagcagaacttcatggtgaccctggaccaggtgttgctccgctgccttgcacac
caacagcactggagccgcctggacgaggagcaggccggcccggagcctggtgagcccaca
tccttgctgctggctccccacccgcccgagccccgtagcaccagctccctcgtcttcagc
tgcatctcccacgccttgctgtggatcagtcaaggccgggaccctgtctttcagccaccc
agtcccccgcagggcctcttcgcccaccctgtggcaggcagcggggccggcgtgctccgt
gaggctgctgccatccacgtgctggtcaccggcagcctgcacctggtgggcggcgtcctg
aagctgctggagccggccctgtcccagtag
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