KEGG   Puma concolor (puma): 112851965
Entry
112851965         CDS       T08890                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
pcoo  Puma concolor (puma)
Pathway
pcoo03015  mRNA surveillance pathway
pcoo04022  cGMP-PKG signaling pathway
pcoo04024  cAMP signaling pathway
pcoo04114  Oocyte meiosis
pcoo04218  Cellular senescence
pcoo04261  Adrenergic signaling in cardiomyocytes
pcoo04270  Vascular smooth muscle contraction
pcoo04390  Hippo signaling pathway
pcoo04510  Focal adhesion
pcoo04611  Platelet activation
pcoo04720  Long-term potentiation
pcoo04728  Dopaminergic synapse
pcoo04750  Inflammatory mediator regulation of TRP channels
pcoo04810  Regulation of actin cytoskeleton
pcoo04910  Insulin signaling pathway
pcoo04921  Oxytocin signaling pathway
pcoo04931  Insulin resistance
pcoo05031  Amphetamine addiction
pcoo05034  Alcoholism
pcoo05168  Herpes simplex virus 1 infection
pcoo05205  Proteoglycans in cancer
pcoo05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pcoo00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    112851965 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    112851965 (PPP1CA)
   04024 cAMP signaling pathway
    112851965 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    112851965 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    112851965 (PPP1CA)
   04218 Cellular senescence
    112851965 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112851965 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112851965 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    112851965 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112851965 (PPP1CA)
   04921 Oxytocin signaling pathway
    112851965 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    112851965 (PPP1CA)
   04270 Vascular smooth muscle contraction
    112851965 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    112851965 (PPP1CA)
   04720 Long-term potentiation
    112851965 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112851965 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    112851965 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    112851965 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    112851965 (PPP1CA)
   05034 Alcoholism
    112851965 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    112851965 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    112851965 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pcoo01009]
    112851965 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:pcoo03021]
    112851965 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:pcoo03019]
    112851965 (PPP1CA)
   03041 Spliceosome [BR:pcoo03041]
    112851965 (PPP1CA)
Enzymes [BR:pcoo01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     112851965 (PPP1CA)
Protein phosphatases and associated proteins [BR:pcoo01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     112851965 (PPP1CA)
Transcription machinery [BR:pcoo03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     112851965 (PPP1CA)
Messenger RNA biogenesis [BR:pcoo03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     112851965 (PPP1CA)
Spliceosome [BR:pcoo03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    112851965 (PPP1CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 112851965
NCBI-ProteinID: XP_025771205
UniProt: A0A6P6H627
LinkDB
Position
Unknown
AA seq 174 aa
MSDSEKLNLDSIIGRLLEGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGW
GENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEF
DNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 525 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctatcatcgggcgcctgctggaaggcctg
tccccggacctgcagtccatggagcagattcggcgtatcatgcggccaacagacgtgcct
gaccagggcttgctatgtgacctgctgtggtctgaccctgacaaggacgtgcagggctgg
ggcgagaatgaccgtggtgtctcctttacctttggggctgaggtagtggccaagttccta
cacaaacacgacttggacctcatctgccgggcacaccaggtggtggaagacggctatgag
ttctttgccaagcggcagctggtgacactcttctcagctcccaactactgtggcgagttt
gacaacgcaggcgccatgatgagtgtggatgagacgctcatgtgctccttccagatcctc
aagcccgctgacaagaacaaggggaaatacgggcagttcagcggcctgaaccctggaggc
cggcccatcaccccaccccgcaactccgccaaagccaagaaatag

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