KEGG   Puma concolor (puma): 112853046
Entry
112853046         CDS       T08890                                 
Symbol
RHOA
Name
(RefSeq) transforming protein RhoA
  KO
K04513  Ras homolog gene family, member A
Organism
pcoo  Puma concolor (puma)
Pathway
pcoo04014  Ras signaling pathway
pcoo04015  Rap1 signaling pathway
pcoo04022  cGMP-PKG signaling pathway
pcoo04024  cAMP signaling pathway
pcoo04062  Chemokine signaling pathway
pcoo04071  Sphingolipid signaling pathway
pcoo04072  Phospholipase D signaling pathway
pcoo04081  Hormone signaling
pcoo04144  Endocytosis
pcoo04150  mTOR signaling pathway
pcoo04270  Vascular smooth muscle contraction
pcoo04310  Wnt signaling pathway
pcoo04350  TGF-beta signaling pathway
pcoo04360  Axon guidance
pcoo04510  Focal adhesion
pcoo04517  IgSF CAM signaling
pcoo04519  Cadherin signaling
pcoo04520  Adherens junction
pcoo04530  Tight junction
pcoo04611  Platelet activation
pcoo04621  NOD-like receptor signaling pathway
pcoo04625  C-type lectin receptor signaling pathway
pcoo04660  T cell receptor signaling pathway
pcoo04670  Leukocyte transendothelial migration
pcoo04722  Neurotrophin signaling pathway
pcoo04810  Regulation of actin cytoskeleton
pcoo04921  Oxytocin signaling pathway
pcoo04928  Parathyroid hormone synthesis, secretion and action
pcoo04972  Pancreatic secretion
pcoo05100  Bacterial invasion of epithelial cells
pcoo05132  Salmonella infection
pcoo05133  Pertussis
pcoo05135  Yersinia infection
pcoo05152  Tuberculosis
pcoo05163  Human cytomegalovirus infection
pcoo05200  Pathways in cancer
pcoo05203  Viral carcinogenesis
pcoo05205  Proteoglycans in cancer
pcoo05206  MicroRNAs in cancer
pcoo05210  Colorectal cancer
pcoo05417  Lipid and atherosclerosis
pcoo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcoo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    112853046 (RHOA)
   04015 Rap1 signaling pathway
    112853046 (RHOA)
   04310 Wnt signaling pathway
    112853046 (RHOA)
   04350 TGF-beta signaling pathway
    112853046 (RHOA)
   04072 Phospholipase D signaling pathway
    112853046 (RHOA)
   04071 Sphingolipid signaling pathway
    112853046 (RHOA)
   04024 cAMP signaling pathway
    112853046 (RHOA)
   04022 cGMP-PKG signaling pathway
    112853046 (RHOA)
   04150 mTOR signaling pathway
    112853046 (RHOA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    112853046 (RHOA)
   04517 IgSF CAM signaling
    112853046 (RHOA)
   04519 Cadherin signaling
    112853046 (RHOA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    112853046 (RHOA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112853046 (RHOA)
   04520 Adherens junction
    112853046 (RHOA)
   04530 Tight junction
    112853046 (RHOA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112853046 (RHOA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    112853046 (RHOA)
   04621 NOD-like receptor signaling pathway
    112853046 (RHOA)
   04625 C-type lectin receptor signaling pathway
    112853046 (RHOA)
   04660 T cell receptor signaling pathway
    112853046 (RHOA)
   04670 Leukocyte transendothelial migration
    112853046 (RHOA)
   04062 Chemokine signaling pathway
    112853046 (RHOA)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    112853046 (RHOA)
   04928 Parathyroid hormone synthesis, secretion and action
    112853046 (RHOA)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    112853046 (RHOA)
  09154 Digestive system
   04972 Pancreatic secretion
    112853046 (RHOA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    112853046 (RHOA)
  09158 Development and regeneration
   04360 Axon guidance
    112853046 (RHOA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112853046 (RHOA)
   05206 MicroRNAs in cancer
    112853046 (RHOA)
   05205 Proteoglycans in cancer
    112853046 (RHOA)
   05203 Viral carcinogenesis
    112853046 (RHOA)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112853046 (RHOA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    112853046 (RHOA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112853046 (RHOA)
   05135 Yersinia infection
    112853046 (RHOA)
   05133 Pertussis
    112853046 (RHOA)
   05152 Tuberculosis
    112853046 (RHOA)
   05100 Bacterial invasion of epithelial cells
    112853046 (RHOA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112853046 (RHOA)
   05418 Fluid shear stress and atherosclerosis
    112853046 (RHOA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pcoo04131]
    112853046 (RHOA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pcoo04147]
    112853046 (RHOA)
   04031 GTP-binding proteins [BR:pcoo04031]
    112853046 (RHOA)
Membrane trafficking [BR:pcoo04131]
 Endocytosis
  Lipid raft mediated endocytosis
   RhoA-dependent endocytosis
    112853046 (RHOA)
Exosome [BR:pcoo04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   112853046 (RHOA)
  Exosomal proteins of other body fluids (saliva and urine)
   112853046 (RHOA)
  Exosomal proteins of colorectal cancer cells
   112853046 (RHOA)
  Exosomal proteins of bladder cancer cells
   112853046 (RHOA)
GTP-binding proteins [BR:pcoo04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    112853046 (RHOA)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU Gtr1_RagA SRPRB VASP_tetra
Other DBs
NCBI-GeneID: 112853046
NCBI-ProteinID: XP_025772395
UniProt: A0A6P6H9G6
LinkDB
Position
Unknown
AA seq 193 aa
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
NT seq 582 nt   +upstreamnt  +downstreamnt
atggctgccatccggaagaaactggtgattgttggtgatggagcctgtggcaagacttgc
ttgctcatcgtcttcagcaaggaccagttcccagaggtgtatgtacccacagtgtttgag
aactatgtggcagatattgaagttgatggaaagcaggtagagttggctttgtgggataca
gctgggcaggaagattatgatcgcttgaggcctctctcctatccggacactgatgttata
ctgatgtgtttctccattgacagccctgatagtttagaaaacatcccagaaaaatggact
ccggaagtcaagcacttctgtcccaatgtgcccatcattctggttggaaacaagaaggat
cttcggaatgatgagcacacaaggcgggagctggccaagatgaagcaggagccggtgaaa
ccagaagaaggcagagatatggcaaacaggattggtgcttttgggtacatggagtgttca
gcaaagaccaaagatggagtgagggaggtttttgaaatggccacaagagccgctctgcaa
gccagacgtgggaagaaaaaatctgggtgccttgtcttgtga

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