KEGG   Puma concolor (puma): 112853975
Entry
112853975         CDS       T08890                                 
Symbol
ITGA2B
Name
(RefSeq) LOW QUALITY PROTEIN: integrin alpha-IIb
  KO
K06476  integrin alpha 2B
Organism
pcoo  Puma concolor (puma)
Pathway
pcoo04015  Rap1 signaling pathway
pcoo04151  PI3K-Akt signaling pathway
pcoo04510  Focal adhesion
pcoo04512  ECM-receptor interaction
pcoo04611  Platelet activation
pcoo04613  Neutrophil extracellular trap formation
pcoo04640  Hematopoietic cell lineage
pcoo04810  Regulation of actin cytoskeleton
pcoo04820  Cytoskeleton in muscle cells
pcoo05165  Human papillomavirus infection
pcoo05200  Pathways in cancer
pcoo05222  Small cell lung cancer
pcoo05410  Hypertrophic cardiomyopathy
pcoo05412  Arrhythmogenic right ventricular cardiomyopathy
pcoo05414  Dilated cardiomyopathy
pcoo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcoo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    112853975 (ITGA2B)
   04151 PI3K-Akt signaling pathway
    112853975 (ITGA2B)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    112853975 (ITGA2B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112853975 (ITGA2B)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    112853975 (ITGA2B)
   04810 Regulation of actin cytoskeleton
    112853975 (ITGA2B)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    112853975 (ITGA2B)
   04611 Platelet activation
    112853975 (ITGA2B)
   04613 Neutrophil extracellular trap formation
    112853975 (ITGA2B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112853975 (ITGA2B)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    112853975 (ITGA2B)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    112853975 (ITGA2B)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    112853975 (ITGA2B)
   05410 Hypertrophic cardiomyopathy
    112853975 (ITGA2B)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    112853975 (ITGA2B)
   05414 Dilated cardiomyopathy
    112853975 (ITGA2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pcoo01009]
    112853975 (ITGA2B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pcoo04147]
    112853975 (ITGA2B)
   04515 Cell adhesion molecules [BR:pcoo04515]
    112853975 (ITGA2B)
   04090 CD molecules [BR:pcoo04090]
    112853975 (ITGA2B)
Protein phosphatases and associated proteins [BR:pcoo01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     112853975 (ITGA2B)
Exosome [BR:pcoo04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   112853975 (ITGA2B)
Cell adhesion molecules [BR:pcoo04515]
 Integrins
  Integrin alpha subunits
   112853975 (ITGA2B)
CD molecules [BR:pcoo04090]
 Proteins
  112853975 (ITGA2B)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_1 Integrin_A_Ig_2 FG-GAP FG-GAP_3 Integrin_alpha ITGAX-like_Ig_3
Other DBs
NCBI-GeneID: 112853975
NCBI-ProteinID: XP_025773200
UniProt: A0A6P6HBQ5
LinkDB
Position
Unknown
AA seq 929 aa
MARAVCPLHALWLLEWVQLLLGPDAVPPAWALNLDPVQLTFYTGPNGSHFGFSLDFYKDS
RGRCAHAQFLTRPLADPSSLPSLAEDKRYCEAGFSSAVTQAGELVLGAPGGYFFLGLLAR
APIADIVSSYRPGTLLWNVPAQRFSADYNNPVYFDGYRGYSVAVGEFDGDINTTEYVLGA
PTWSWTLGAVEILNSYHQTLHRLHGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESR
ADRKLAEVGRVYLFLQPRGHHPLGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDVAVA
APYGGPSGRGQVLVFLGQSEGLSSRPSQILDSPFPTGSGFGFSLRGGTDIDDNGYPDLLV
GAYGANQVAVYRAQPVVMANVQLLVQDSLNPAVKNCVLPQTQTPVSCFNIQMCVGVTGHS
IPQKLPLHAELQLDRQKPRQGRRVLLLNSQQAGTTLHLDLGGRHSPICHSTMAFLRDEAD
FRDKLSPIVLSFNVSLQPEKDGIPPELVLHGDTHVQQQTRIILDCGEDDLCVPQLQLTAN
VMGSPLLIGADNVLASLNGYINEGXGPRGGEAQLSHTPGAHYMRAISNIEGFERLICNQK
KENETKVVLCELGNPMKKNARMGITMLVSVGDLEEAGEHVSFWLQIRSKNSQNPNSEAVQ
LDVPVRAKAHMELRGNSFPASLLMVAEEGNGENNSDSWGPKVEHTYELHNNGPSTVSGLH
LSLSFPSQSQPSDLLYILDIQPQGGLQCSPQPAPNPLKLDWGLPTPSPSPIYTGHHKRDR
RQALLPGSNQPSRLQDPVHLSCDSVPCTVVQCELQEMARGQRAMVTVLAFLWLPSLQQRP
LDQFVLKSKAWFNVSSFPYSVPALSLPSEEVTVETQLLRVLEERDIPIWWVLLGVLGGLL
LLTVLVLAMWKVGFFKRVRPPLEEDEEEE
NT seq 2790 nt   +upstreamnt  +downstreamnt
atggccagagctgtgtgtccacttcatgccctctggcttctggagtgggtgcagctgctc
ttgggacccgatgctgtccctccagcctgggccttgaacctggacccagtgcagctcacc
ttctacacaggccccaatggcagccactttgggttttcgctggacttctacaaggacagc
cgtgggaggtgcgcccacgcacaattcttgacccgccccctcgctgacccctcctctttg
ccttctctagccgaagacaagcgctactgcgaagcgggcttcagctccgcggtcactcag
gctggagagctggtgcttggggcccctggcggctattttttcttaggtctcctggcgcga
gctcctattgccgatatcgtctcgagttaccgcccaggcaccctcttgtggaacgtgccc
gcccagcgcttctccgcagactacaacaacccagtgtacttcgacggctaccgggggtac
tcggtggccgtgggcgagttcgacggggatatcaacactacagagtatgtcttaggcgcc
cccacctggagctggaccctgggagcggtggaaattttgaactcgtaccaccagacgctg
caccggctgcacggagagcagatggcttcgtatttcgggcactcggtggccgtcactgat
gtcaacggggacgggaggcacgacctgctggtgggcgcgccactgtacatggagagccgc
gctgaccgcaaactggccgaggtggggcgtgtgtacttgttcctgcagcctcgcggtcac
cacccactgggcgcccccagccttctgctgacgggcacacagctctacgggagattcggc
tccgccatcgcgcctctgggcgacctcgaccgggacggctacaacgatgttgcagtggcc
gccccctatgggggtcccagtggtcggggccaagtgctggtgttcctgggtcagagtgag
gggcttagctcacgcccctcccagatcctggacagccccttccccacaggctctggcttc
ggcttctccctgcgaggtggcacagacatcgatgacaacggatacccagacctactggta
ggagcttatggggctaaccaggtggctgtgtacagagctcagccagtggtgatggccaat
gtgcagctgctggtgcaagattcactgaatcctgctgtgaagaactgtgtcctgccccag
acccagacaccagtgagctgctttaacatccagatgtgtgtaggagtcactgggcacagc
attcctcagaagctgcccctacacgctgagctgcagctggaccggcagaagcctcgccag
ggccggcgggtgctactgctgaattctcaacaggcgggcaccaccctgcatctggacctg
ggcgggaggcacagccccatctgccactccaccatggccttcctccgggatgaggctgac
ttccgggacaagctgagccccatcgtgctcagcttcaatgtgtccctgcagcccgagaag
gacggaataccccccgagctcgtgcttcacggggacacccatgtccagcagcagacccgc
atcatcctggactgcggagaggatgatctgtgtgtgccccagctccagctcaccgccaac
gtgatgggctccccactcctcattggagctgacaatgtgctggcaagcctgaatggatac
attaatgagggannggggcctagaggcggggaggcacagttgtcgcataccccaggtgcc
cactacatgagggccatcagcaacattgagggctttgagagactcatctgtaaccagaag
aaagagaatgagaccaaggtggtgctgtgtgagctgggcaacccgatgaagaaaaatgcc
cggatgggaatcacgatgttggtgagcgtgggggacctggaagaggctggggagcatgtg
tccttctggctgcagatcagaagcaagaatagccagaatccaaacagcgaggctgtgcag
ctggatgtaccagtccgggcaaaggcccacatggaactgcgagggaactcctttccagcc
tccttgctgatggtggcggaagaaggcaacggggagaacaactcggacagctggggcccc
aaagttgagcacacctatgagctccataacaatggccccagcactgtaagtggcctccac
ctcagccttagctttcccagccagtcccagccctctgacctgctctacatcttggatata
cagcctcagggggggcttcaatgctccccacagccggctcctaaccccctcaagctggac
tgggggctgcctacccccagcccttcccccatttacacggggcatcacaagcgggaccgc
agacaggccctcctgccagggtccaaccagccctccaggcttcaggatccagttcacctg
agctgcgactcagtgccctgtacagtggtgcagtgtgagctacaggagatggcacgaggg
cagcgggccatggtcacggtgctggccttcctgtggctgcccagcctccagcagaggcca
ctggatcagttcgtgctaaagtcaaaagcttggttcaacgtctcctcctttccttactct
gtgcccgccctcagcctgcccagtgaagaagttacggtcgagacgcagctgcttcgtgtc
ttggaggagagagacattccaatctggtgggtgctgttaggcgtattgggcggcctgctg
ttgctcacggtcctggtcctggccatgtggaaggttggcttcttcaagcgtgttcggcca
ccactagaagaagatgaagaggaggagtga

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